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CATH Superfamily 3.10.290.10

RNA-binding S4 domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
RNA-binding S4 domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 13679: 23S rRNA pseudouridine synthase F

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
23S rRNA pseudouridine(2604) synthase. [EC: 5.4.99.21]
23S rRNA uridine(2604) = 23S rRNA pseudouridine(2604).
  • The enzyme is not completely specific for uridine(2604) and can, to a small extent, also react with uridine(2605).
 216 A0A024L713 A0A024L713 A0A029HCP4 A0A029HCP4 A0A029IGN4 A0A029IGN4 A0A029L904 A0A029L904 A0A069XFN2 A0A069XFN2
(206 more...)
Pseudouridylate synthase. [EC: 4.2.1.70]
Uracil + D-ribose 5-phosphate = pseudouridine 5'-phosphate + H(2)O.
  • The reaction it readily reversible.
  • While the enzymes from Tetrahymena pyriformis and Agrobacterium tumefaciens produce pseudouridine 5'-phosphate the enzyme from Escherichia coli functions as a pseudouridine-5'-phosphate glycosidase in vivo.
 4 W1DIR1 W1DIR1 W1E1A8 W1E1A8