CATH Superfamily 3.10.260.10
Transcription regulator HTH, APSES-type DNA-binding domain
The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:
"Transcription regulator HTH, APSES-type DNA-binding domain
".
FunFam 466: Transcription factor Mbp1
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 7 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding GO:0001077
Interacting selectively and non-covalently with a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase II (RNAP II) in order to activate or increase the frequency, rate or extent of transcription from the RNAP II promoter.
|
5 | P01129 (/IMP) P25302 (/IMP) P33520 (/IMP) P39678 (/IMP) P41412 (/IMP) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
5 | P01129 (/IPI) P25302 (/IPI) P33520 (/IPI) P39678 (/IPI) P41412 (/IPI) |
|
RNA polymerase II core promoter proximal region sequence-specific DNA binding GO:0000978
Interacting selectively and non-covalently with a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase II.
|
2 | P01129 (/IC) P41412 (/IC) |
|
RNA polymerase II core promoter proximal region sequence-specific DNA binding GO:0000978
Interacting selectively and non-covalently with a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase II.
|
1 | P01129 (/IDA) |
|
Transcription factor activity, RNA polymerase II core promoter sequence-specific GO:0000983
Interacting selectively and non-covalently with a specific DNA sequence in an RNA polymerase II (Pol II) core promoter, the region composed of the transcription start site and binding sites for transcription factors of the Pol II basal transcription machinery, in order to modulate transcription by Pol II. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.
|
1 | P33520 (/IMP) |
|
Transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding GO:0001077
Interacting selectively and non-covalently with a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase II (RNAP II) in order to activate or increase the frequency, rate or extent of transcription from the RNAP II promoter.
|
1 | P01129 (/TAS) |
|
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
1 | P25302 (/IPI) |
There are 10 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Regulation of transcription involved in G1/S transition of mitotic cell cycle GO:0000083
Any process that regulates transcription such that the target genes are involved in the transition between G1 and S phase of the mitotic cell cycle.
|
4 | A0A1D8PCM9 (/IMP) A0A1D8PJV0 (/IMP) P01129 (/IMP) P33520 (/IMP) |
|
Positive regulation of transcription from RNA polymerase II promoter GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
4 | P01129 (/IMP) P33520 (/IMP) P41412 (/IMP) Q5B8H6 (/IMP) |
|
Positive regulation of transcription involved in G1/S transition of mitotic cell cycle GO:0071931
Any process that activates or increases transcription as part of the G1/S transition of the mitotic cell cycle.
|
4 | P25302 (/IMP) P33520 (/IMP) P39678 (/IMP) P41412 (/IMP) |
|
Regulation of transcription involved in G1/S transition of mitotic cell cycle GO:0000083
Any process that regulates transcription such that the target genes are involved in the transition between G1 and S phase of the mitotic cell cycle.
|
2 | A0A1D8PCM9 (/IGI) A0A1D8PJV0 (/IGI) |
|
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
|
1 | P41412 (/IDA) |
|
RRNA transcription GO:0009303
The synthesis of ribosomal RNA (rRNA), any RNA that forms part of the ribosomal structure, from a DNA template.
|
1 | P01129 (/IDA) |
|
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
|
1 | P01129 (/IDA) |
|
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
|
1 | P01129 (/IDA) |
|
Regulation of meiotic cell cycle GO:0051445
Any process that modulates the rate or extent of progression through the meiotic cell cycle.
|
1 | P41412 (/IMP) |
|
Positive regulation of transcription from RNA polymerase II promoter in response to heat stress GO:0061408
Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
|
1 | P25302 (/IMP) |
There are 8 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nuclear chromatin GO:0000790
The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome in the nucleus.
|
4 | P01129 (/IDA) P25302 (/IDA) P33520 (/IDA) P41412 (/IDA) |
|
MBF transcription complex GO:0030907
A protein complex that binds to the Mlu1 cell cycle box (MCB) promoter element, consensus sequence ACGCGN, and is involved in regulation of transcription during the G1/S transition of the cell cycle. In Saccharomyces, the complex contains a heterodimer of the DNA binding protein Mbp1p and the activator Swi4p, and is associated with additional proteins known as Nrm1p, Msa1p, and Msa2p; in Schizosaccharomyces the complex contains Res1p, Res2p, and Cdc10p.
|
4 | P01129 (/IDA) P33520 (/IDA) P39678 (/IDA) P41412 (/IDA) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
2 | P33520 (/IDA) P41412 (/IDA) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
2 | P01129 (/IDA) P41412 (/IDA) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | P41412 (/IDA) |
|
SBF transcription complex GO:0033309
A protein complex that binds to the Swi4/6 cell cycle box (SCB) promoter element, consensus sequence CRCGAAA, and activates transcription during the G1/S transition of the cell cycle. In Saccharomyces, the complex contains a heterodimer of the DNA binding protein Swi6p and the activator Swi4p, and is associated with additional proteins known as Whi5p and Msa1p.
|
1 | P25302 (/IDA) |
|
SBF transcription complex GO:0033309
A protein complex that binds to the Swi4/6 cell cycle box (SCB) promoter element, consensus sequence CRCGAAA, and activates transcription during the G1/S transition of the cell cycle. In Saccharomyces, the complex contains a heterodimer of the DNA binding protein Swi6p and the activator Swi4p, and is associated with additional proteins known as Whi5p and Msa1p.
|
1 | P25302 (/IMP) |
|
SBF transcription complex GO:0033309
A protein complex that binds to the Swi4/6 cell cycle box (SCB) promoter element, consensus sequence CRCGAAA, and activates transcription during the G1/S transition of the cell cycle. In Saccharomyces, the complex contains a heterodimer of the DNA binding protein Swi6p and the activator Swi4p, and is associated with additional proteins known as Whi5p and Msa1p.
|
1 | P25302 (/IPI) |
