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CATH Superfamily 3.10.20.30

Beta-grasp domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 22573: Succinate dehydrogenase iron-sulfur subunit

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Deleted entry. [EC: 1.3.99.1]
    		214 A0A023PD23 A0A045GLJ1 A0A063CND4 A0A080UQ57 A0A083WMQ8 A0A084IV13 A0A090IX03 A0A0A0TZQ6 A0A0B0QF81 A0A0B5QZ02
    (204 more...)
    Succinate dehydrogenase (quinone). [EC: 1.3.5.1]
    Succinate + a quinone = fumarate + a quinol.
    • The enzyme is found in the inner mitochondrial membrane in eukaryotes and the plasma membrane of many aerobic or facultative bacteria.
    • It catalyzes succinate oxidation in the citric acid cycle and transfers the electrons to quinones in the membrane, thus constituting a part of the aerobic respiratory chain (known as complex II).
    • In vivo the enzyme uses the quinone found in the organism - eukaryotic enzymes utilize ubiquinone, bacterial enzymes utilize ubiquinone or menaquinone, and archaebacterial enzymes from the Sulfolobus genus use caldariellaquinone.
    • Cf. EC 1.3.5.4.
    		 122 A0A023PD23 A0A063CND4 A0A063XGI8 A0A0A0TZQ6 A0A0A2SNA1 A0A0B5QZ02 A0A0B5Z1N1 A0A0B6BLH3 A0A0D0G9F2 A0A0D0IA86
    (112 more...)
    Fumarate reductase (quinol). [EC: 1.3.5.4]
    Succinate + a quinone = fumarate + a quinol.
    • The enzyme, which is found in anaerobic and facultative organisms such as bacteria, parasitic helminthes, and lower marine organisms, utilizes low potential quinols, such as menaquinol and rhodoquinol, to reduce fumarate as the final step of an anaerobic respiratory chain.
    • The enzyme is known as complex II of the electron transfer chain, similarly to EC 1.3.5.1, to which it is closely related.
    		 6 A0A0A0TZQ6 A0A120KSZ9 A0A1A0D283 A0A1A5VFG6 A0A1D9PMS7 E1UMI9