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CATH Superfamily 3.10.20.30

Beta-grasp domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 22537: Phenol hydroxylase, Ferredoxin subunit

There are 4 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Phenol 2-monooxygenase (NADPH). [EC: 1.14.13.7]
Phenol + NADPH + O(2) = catechol + NADP(+) + H(2)O.
  • The enzyme from the fungus Trichosporon cutaneum has a broad substrate specificity, and has been reported to catalyze the hydroxylation of a variety of substituted phenols, such as fluoro-, chloro-, amino- and methyl-phenols and also dihydroxybenzenes.
  • Cf. EC 1.14.14.20.
 109 A0A009HAA4 A0A009HH90 A0A009K117 A0A009MX92 A0A010K7M2 A0A010MD22 A0A010ULA0 A0A011DP67 A0A011J6Z6 A0A013KKT3
(99 more...)
Ferredoxin--NAD(+) reductase. [EC: 1.18.1.3]
Reduced ferredoxin + NAD(+) = oxidized ferredoxin + NADH.
  • The reaction is written for a [2Fe-2S] ferredoxin, which is characteristic of some mono- and dioxygenase systems.
  • some anaerobic bacteria have a 2[4Fe-4S] ferredoxin, which transfers two electrons.
 24 A0A059MFL8 A0A069B2U4 A0A098BFN9 A0A0D5G7S3 A0A0E1URH3 A0A0E1W1E8 A0A0F6GGJ3 A0A0F6L5Z7 A0A0H2WLB7 A0A0H3HLJ1
(14 more...)
Methane monooxygenase (soluble). [EC: 1.14.13.25]
Methane + NAD(P)H + O(2) = methanol + NAD(P)(+) + H(2)O.
  • The enzyme is soluble, in contrast to the particulate enzyme, EC 1.14.18.3.
  • Broad specificity; many alkanes can be hydroxylated, and alkenes are converted into the corresponding epoxides; CO is oxidized to CO(2), ammonia is oxidized to hydroxylamine, and some aromatic compounds and cyclic alkanes can also be hydroxylated, but more slowly.
 10 A0A059MFL8 A0A098BFN9 A0A0H4NX28 A0A143QJR0 A0A161GD97 A0A1C3REV4 N1MDI9 P22868 Q53563 W4A6I0
CDP-4-dehydro-6-deoxyglucose reductase. [EC: 1.17.1.1]
CDP-4-dehydro-3,6-dideoxy-D-glucose + NAD(P)(+) + H(2)O = CDP-4-dehydro- 6-deoxy-D-glucose + NAD(P)H.
  • The enzyme consists of two proteins.
  • One forms an enzyme-bound adduct of the CDP-4-dehydro-6-deoxyglucose with pyridoxamine phosphate, in which the 3-hydroxy group has been removed.
  • The second catalyzes the reduction of this adduct by NAD(P)H and release of the CDP-4-dehydro-3,6-dideoxy-D-glucose and pyridoxamine phosphate.
 8 A0A062WZW3 A0A085EUQ1 A0A0B3RRQ9 A0A0E3ZN01 A0A0P8CU89 A0A1E3DCH7 Q2JA06 Q3J2G2