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CATH Superfamily 3.10.20.30

Beta-grasp domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 22191: (P)ppGpp synthetase I, SpoT/RelA

There are 5 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Guanosine-3',5'-bis(diphosphate) 3'-diphosphatase. [EC: 3.1.7.2]
Guanosine 3',5'-bis(diphosphate) + H(2)O = guanosine 5'-diphosphate + diphosphate.
    		 732 A0A017I3Q2 A0A022PGX7 A0A023Z4J5 A0A024HQK4 A0A024KSZ7 A0A025CJL0 A0A026S1E2 A0A026UXD3 A0A027U6L2 A0A028AHQ8
    (722 more...)
    GTP diphosphokinase. [EC: 2.7.6.5]
    ATP + GTP = AMP + guanosine 3'-diphosphate 5'-triphosphate.
    • GDP can also act as acceptor.
    		 555 A0A023Z4J5 A0A024KSZ7 A0A025CJL0 A0A026S1E2 A0A026UXD3 A0A027U6L2 A0A028AHQ8 A0A028EAY1 A0A029HFT3 A0A029IJD2
    (545 more...)
    Phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent). [EC: 5.4.2.2]
    Alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate.
    • Maximum activity is only obtained in the presence of alpha-D-glucose 1,6-bisphosphate.
    • This bisphosphate is an intermediate in the reaction, being formed by transfer of a phosphate residue from the enzyme to the substrate, but the dissociation of bisphosphate from the enzyme complex is much slower than the overall isomerization.
    • Also, more slowly, catalyzes the interconversion of 1-phosphate and 6-phosphate isomers of many other alpha-D-hexoses, and the interconversion of alpha-D-ribose 1-phosphate and 5-phosphate.
    • Cf. EC 5.4.2.5.
    • Formerly EC 2.7.5.1.
    		 6 A0A0F4XKE5 A0A1H0WWX6 F2K6Y2 G8Q6Z0 I4JYU2 S6JSK2
    Threonine--tRNA ligase. [EC: 6.1.1.3]
    ATP + L-threonine + tRNA(Thr) = AMP + diphosphate + L-threonyl-tRNA(Thr).
      		 1 A0A068RDP3
      Glutamate racemase. [EC: 5.1.1.3]
      L-glutamate = D-glutamate.
        		 1 A5UFH2