The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 22167: Benzoate 1,2-Dioxygenase Reductase

There are 4 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Ferredoxin--NAD(+) reductase. [EC: 1.18.1.3]
Reduced ferredoxin + NAD(+) = oxidized ferredoxin + NADH.
  • The reaction is written for a [2Fe-2S] ferredoxin, which is characteristic of some mono- and dioxygenase systems.
  • some anaerobic bacteria have a 2[4Fe-4S] ferredoxin, which transfers two electrons.
316 A0A009FU41 A0A009FU41 A0A009GVB4 A0A009GVB4 A0A009HAA0 A0A009HAA0 A0A009HH83 A0A009HH83 A0A009I191 A0A009I191
(306 more...)
Benzoate 1,2-dioxygenase. [EC: 1.14.12.10]
Benzoate + NADH + O(2) = (1R,6S)-1,6-dihydroxycyclohexa-2,4-diene-1- carboxylate + NAD(+).
  • A system, containing a reductase which is an iron-sulfur flavoprotein (FAD), and an iron-sulfur oxygenase.
  • Formerly EC 1.13.99.2.
52 A0A069BHJ3 A0A069BHJ3 A0A0D5HPX8 A0A0D5HPX8 A0A0D6VFP4 A0A0D6VFP4 A0A0E1SH14 A0A0E1SH14 A0A0E1TXP3 A0A0E1TXP3
(42 more...)
Dihydroorotate oxidase (fumarate). [EC: 1.3.98.1]
(S)-dihydroorotate + fumarate = orotate + succinate.
  • The reaction, which takes place in the cytosol, is the only redox reaction in the de novo biosynthesis of pyrimidine nucleotides.
  • Molecular oxygen can replace fumarate in vitro.
  • Other class 1 dihydroorotate dehydrogenases use either NAD(+) (EC 1.3.1.14) or NADP(+) (EC 1.3.1.15) as electron acceptor.
  • The membrane bound class 2 dihydroorotate dehydrogenase (EC 1.3.5.2) uses quinone as electron acceptor.
  • Formerly EC 1.3.3.1.
4 A0A0T8LGM4 A0A0T8LGM4 A0A1G3DKA3 A0A1G3DKA3
Nitric oxide dioxygenase. [EC: 1.14.12.17]
2 nitric oxide + 2 O(2) + NAD(P)H = 2 nitrate + NAD(P)(+) + H(+).
  • It has been proposed that FAD functions as the electron carrier from NADPH to the ferric heme prosthetic group.
2 A0A0D6T3G0 A0A0D6T3G0