The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 25427: Probable 4-hydroxyphenylpyruvate dioxygenase 1

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
4-hydroxyphenylpyruvate dioxygenase. [EC: 1.13.11.27]
4-hydroxyphenylpyruvate + O(2) = homogentisate + CO(2).
  • Formerly EC 1.14.2.2 and EC 1.99.1.14.
430 A0A023P1T8 A0A061I2G5 A0A066YPR6 A0A068N530 A0A075FVH8 A0A075GNB4 A0A075H2U8 A0A075IB08 A0A075R8T7 A0A075S5B3
(420 more...)
4-hydroxymandelate synthase. [EC: 1.13.11.46]
4-hydroxyphenylpyruvate + O(2) = (S)-4-hydroxymandelate + CO(2).
  • Involved in the biosynthesis of the vancomycin group of glycopeptide antibiotics.
1 O52791
Lactoylglutathione lyase. [EC: 4.4.1.5]
(R)-S-lactoylglutathione = glutathione + methylglyoxal.
  • Also acts on 3-phosphoglycerol-glutathione.
1 A0A161MTI1
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