The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:
"Mannose-Binding Protein A, subunit A
".
FunFam 12299: C-type lectin-domain family 2 member F
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 6 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Transmembrane signaling receptor activity GO:0004888
Combining with an extracellular or intracellular signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity or state as part of signal transduction.
|
3 | Q8C1T8 (/ISS) Q91V08 (/ISS) Q9WVF9 (/ISS) |
|
Carbohydrate binding GO:0030246
Interacting selectively and non-covalently with any carbohydrate, which includes monosaccharides, oligosaccharides and polysaccharides as well as substances derived from monosaccharides by reduction of the carbonyl group (alditols), by oxidation of one or more hydroxy groups to afford the corresponding aldehydes, ketones, or carboxylic acids, or by replacement of one or more hydroxy group(s) by a hydrogen atom. Cyclitols are generally not regarded as carbohydrates.
|
3 | Q8C1T8 (/ISS) Q91V08 (/ISS) Q9WVF9 (/ISS) |
|
Natural killer cell lectin-like receptor binding GO:0046703
Interacting selectively and non-covalently with a lectin-like natural killer cell receptor.
|
3 | Q8C1T8 (/IPI) Q9D676 (/IPI) Q9WVF9 (/IPI) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
2 | Q91V08 (/IPI) Q9WVF9 (/IPI) |
|
Natural killer cell lectin-like receptor binding GO:0046703
Interacting selectively and non-covalently with a lectin-like natural killer cell receptor.
|
2 | Q91V08 (/IDA) Q9WVF9 (/IDA) |
|
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
|
1 | Q8VI21 (/ISO) |
There are 12 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cellular defense response GO:0006968
A defense response that is mediated by cells.
|
2 | Q8C1T8 (/TAS) Q91V08 (/TAS) |
|
Negative regulation of osteoclast differentiation GO:0045671
Any process that stops, prevents, or reduces the frequency, rate or extent of osteoclast differentiation.
|
2 | Q91V08 (/IDA) Q9D676 (/IDA) |
|
Membrane raft assembly GO:0001765
The aggregation, arrangement and bonding together of a set of components to form a membrane raft, a small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalizes cellular processes.
|
1 | Q9WVF9 (/NAS) |
|
Regulation of actin filament polymerization GO:0030833
Any process that modulates the frequency, rate or extent of the assembly of actin filaments by the addition of actin monomers to a filament.
|
1 | Q9WVF9 (/IMP) |
|
Regulation of T cell proliferation GO:0042129
Any process that modulates the frequency, rate or extent of T cell proliferation.
|
1 | Q9WVF9 (/IMP) |
|
Protection from natural killer cell mediated cytotoxicity GO:0042270
The process of protecting a cell from natural killer cell mediated cytotoxicity.
|
1 | Q91V08 (/IDA) |
|
Protection from natural killer cell mediated cytotoxicity GO:0042270
The process of protecting a cell from natural killer cell mediated cytotoxicity.
|
1 | Q91V08 (/IGI) |
|
Receptor clustering GO:0043113
The receptor metabolic process that results in grouping of a set of receptors at a cellular location, often to amplify the sensitivity of a signaling response.
|
1 | Q9WVF9 (/IMP) |
|
Regulation of interleukin-2 biosynthetic process GO:0045076
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-2.
|
1 | Q9WVF9 (/IMP) |
|
Negative regulation of osteoclast differentiation GO:0045671
Any process that stops, prevents, or reduces the frequency, rate or extent of osteoclast differentiation.
|
1 | Q9WVF9 (/NAS) |
|
T cell receptor signaling pathway GO:0050852
A series of molecular signals initiated by the cross-linking of an antigen receptor on a T cell.
|
1 | Q9WVF9 (/IMP) |
|
Positive regulation of immunological synapse formation GO:2000522
Any process that activates or increases the frequency, rate or extent of immunological synapse formation.
|
1 | Q9WVF9 (/NAS) |
There are 5 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
2 | Q8C1T8 (/TAS) Q91V08 (/TAS) |
|
External side of plasma membrane GO:0009897
The leaflet of the plasma membrane that faces away from the cytoplasm and any proteins embedded or anchored in it or attached to its surface.
|
2 | Q91V08 (/IDA) Q9WVF9 (/IDA) |
|
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
|
1 | Q9D676 (/IC) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
1 | Q8VI21 (/ISO) |
|
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
|
1 | Q9WVF9 (/IDA) |