The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Mannose-Binding Protein A, subunit A
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 12138: Secretory phospholipase A2 receptor

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 6 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Receptor activity GO:0004872
Combining with an extracellular or intracellular messenger to initiate a change in cell activity.
11 F1M495 (/ISS) F1PGC5 (/ISS) F6Y1A5 (/ISS) F7CUS6 (/ISS) G1L1S3 (/ISS) G1PP42 (/ISS) G1QLJ9 (/ISS) P49259 (/ISS) P49260 (/ISS) Q5R880 (/ISS)
(1 more)
Phospholipase binding GO:0043274
Interacting selectively and non-covalently with any phospholipase, enzymes that catalyze of the hydrolysis of a glycerophospholipid.
10 F1M495 (/ISS) F1PGC5 (/ISS) F6Y1A5 (/ISS) F7CUS6 (/ISS) G1L1S3 (/ISS) G1PP42 (/ISS) G1QLJ9 (/ISS) P49259 (/ISS) P49260 (/ISS) Q5R880 (/ISS)
Phospholipase binding GO:0043274
Interacting selectively and non-covalently with any phospholipase, enzymes that catalyze of the hydrolysis of a glycerophospholipid.
2 Q13018 (/IPI) Q62028 (/IPI)
Receptor activity GO:0004872
Combining with an extracellular or intracellular messenger to initiate a change in cell activity.
1 Q13018 (/IDA)
Receptor activity GO:0004872
Combining with an extracellular or intracellular messenger to initiate a change in cell activity.
1 Q62028 (/ISO)
Phospholipase binding GO:0043274
Interacting selectively and non-covalently with any phospholipase, enzymes that catalyze of the hydrolysis of a glycerophospholipid.
1 Q62028 (/ISO)

There are 24 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytokine production GO:0001816
The appearance of a cytokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
11 F1M495 (/ISS) F1PGC5 (/ISS) F6Y1A5 (/ISS) F7CUS6 (/ISS) G1L1S3 (/ISS) G1PP42 (/ISS) G1QLJ9 (/ISS) P49259 (/ISS) P49260 (/ISS) Q5R880 (/ISS)
(1 more)
Positive regulation of DNA damage response, signal transduction by p53 class mediator GO:0043517
Any process that activates, maintains or increases the rate of the cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage.
11 F1M495 (/ISS) F1PGC5 (/ISS) F6Y1A5 (/ISS) F7CUS6 (/ISS) G1L1S3 (/ISS) G1PP42 (/ISS) G1QLJ9 (/ISS) P49259 (/ISS) P49260 (/ISS) Q5R880 (/ISS)
(1 more)
Reactive oxygen species metabolic process GO:0072593
The chemical reactions and pathways involving a reactive oxygen species, any molecules or ions formed by the incomplete one-electron reduction of oxygen. They contribute to the microbicidal activity of phagocytes, regulation of signal transduction and gene expression, and the oxidative damage to biopolymers.
11 F1M495 (/ISS) F1PGC5 (/ISS) F6Y1A5 (/ISS) F7CUS6 (/ISS) G1L1S3 (/ISS) G1PP42 (/ISS) G1QLJ9 (/ISS) P49259 (/ISS) P49260 (/ISS) Q5R880 (/ISS)
(1 more)
Positive regulation of arachidonic acid secretion GO:0090238
Any process that increases the rate, frequency, or extent of arachidonic acid secretion, the controlled release of arachidonic acid from a cell or a tissue.
11 F1M495 (/ISS) F1PGC5 (/ISS) F6Y1A5 (/ISS) F7CUS6 (/ISS) G1L1S3 (/ISS) G1PP42 (/ISS) G1QLJ9 (/ISS) P49259 (/ISS) P49260 (/ISS) Q13018 (/ISS)
(1 more)
Replicative senescence GO:0090399
A cell aging process associated with the dismantling of a cell as a response to telomere shortening and/or cellular aging.
11 F1M495 (/ISS) F1PGC5 (/ISS) F6Y1A5 (/ISS) F7CUS6 (/ISS) G1L1S3 (/ISS) G1PP42 (/ISS) G1QLJ9 (/ISS) P49259 (/ISS) P49260 (/ISS) Q5R880 (/ISS)
(1 more)
Oxidative stress-induced premature senescence GO:0090403
A cellular senescence process associated with the dismantling of a cell as a response to oxidative stress, e.g. high levels of reactive oxygen species, such as superoxide anions, hydrogen peroxide, and hydroxyl radicals.
11 F1M495 (/ISS) F1PGC5 (/ISS) F6Y1A5 (/ISS) F7CUS6 (/ISS) G1L1S3 (/ISS) G1PP42 (/ISS) G1QLJ9 (/ISS) P49259 (/ISS) P49260 (/ISS) Q5R880 (/ISS)
(1 more)
Receptor-mediated endocytosis GO:0006898
An endocytosis process in which cell surface receptors ensure specificity of transport. A specific receptor on the cell surface binds tightly to the extracellular macromolecule (the ligand) that it recognizes; the plasma-membrane region containing the receptor-ligand complex then undergoes endocytosis, forming a transport vesicle containing the receptor-ligand complex and excluding most other plasma-membrane proteins. Receptor-mediated endocytosis generally occurs via clathrin-coated pits and vesicles.
10 F1M495 (/ISS) F1PGC5 (/ISS) F6Y1A5 (/ISS) F7CUS6 (/ISS) G1L1S3 (/ISS) G1PP42 (/ISS) G1QLJ9 (/ISS) P49259 (/ISS) P49260 (/ISS) Q5R880 (/ISS)
Receptor-mediated endocytosis GO:0006898
An endocytosis process in which cell surface receptors ensure specificity of transport. A specific receptor on the cell surface binds tightly to the extracellular macromolecule (the ligand) that it recognizes; the plasma-membrane region containing the receptor-ligand complex then undergoes endocytosis, forming a transport vesicle containing the receptor-ligand complex and excluding most other plasma-membrane proteins. Receptor-mediated endocytosis generally occurs via clathrin-coated pits and vesicles.
2 Q13018 (/IDA) Q62028 (/IDA)
Cytokine production GO:0001816
The appearance of a cytokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
1 Q13018 (/IMP)
Cytokine production GO:0001816
The appearance of a cytokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
1 Q62028 (/ISO)
Receptor-mediated endocytosis GO:0006898
An endocytosis process in which cell surface receptors ensure specificity of transport. A specific receptor on the cell surface binds tightly to the extracellular macromolecule (the ligand) that it recognizes; the plasma-membrane region containing the receptor-ligand complex then undergoes endocytosis, forming a transport vesicle containing the receptor-ligand complex and excluding most other plasma-membrane proteins. Receptor-mediated endocytosis generally occurs via clathrin-coated pits and vesicles.
1 Q62028 (/ISO)
Positive regulation of DNA damage response, signal transduction by p53 class mediator GO:0043517
Any process that activates, maintains or increases the rate of the cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage.
1 Q13018 (/IMP)
Positive regulation of DNA damage response, signal transduction by p53 class mediator GO:0043517
Any process that activates, maintains or increases the rate of the cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage.
1 Q62028 (/ISO)
Reactive oxygen species metabolic process GO:0072593
The chemical reactions and pathways involving a reactive oxygen species, any molecules or ions formed by the incomplete one-electron reduction of oxygen. They contribute to the microbicidal activity of phagocytes, regulation of signal transduction and gene expression, and the oxidative damage to biopolymers.
1 Q13018 (/IDA)
Reactive oxygen species metabolic process GO:0072593
The chemical reactions and pathways involving a reactive oxygen species, any molecules or ions formed by the incomplete one-electron reduction of oxygen. They contribute to the microbicidal activity of phagocytes, regulation of signal transduction and gene expression, and the oxidative damage to biopolymers.
1 Q62028 (/ISO)
Positive regulation of arachidonic acid secretion GO:0090238
Any process that increases the rate, frequency, or extent of arachidonic acid secretion, the controlled release of arachidonic acid from a cell or a tissue.
1 Q62028 (/IDA)
Replicative senescence GO:0090399
A cell aging process associated with the dismantling of a cell as a response to telomere shortening and/or cellular aging.
1 Q13018 (/IMP)
Replicative senescence GO:0090399
A cell aging process associated with the dismantling of a cell as a response to telomere shortening and/or cellular aging.
1 Q62028 (/ISO)
Oxidative stress-induced premature senescence GO:0090403
A cellular senescence process associated with the dismantling of a cell as a response to oxidative stress, e.g. high levels of reactive oxygen species, such as superoxide anions, hydrogen peroxide, and hydroxyl radicals.
1 Q13018 (/IMP)
Oxidative stress-induced premature senescence GO:0090403
A cellular senescence process associated with the dismantling of a cell as a response to oxidative stress, e.g. high levels of reactive oxygen species, such as superoxide anions, hydrogen peroxide, and hydroxyl radicals.
1 Q62028 (/ISO)
Negative regulation of phospholipase A2 activity GO:1900138
Any process that stops, prevents or reduces the frequency, rate or extent of phospholipase A2 activity.
1 Q62028 (/IDA)
Negative regulation of phospholipase A2 activity GO:1900138
Any process that stops, prevents or reduces the frequency, rate or extent of phospholipase A2 activity.
1 Q13018 (/ISS)
Negative regulation of arachidonic acid secretion GO:1900139
Any process that stops, prevents or reduces the frequency, rate or extent of arachidonic acid secretion.
1 Q62028 (/IDA)
Negative regulation of arachidonic acid secretion GO:1900139
Any process that stops, prevents or reduces the frequency, rate or extent of arachidonic acid secretion.
1 Q13018 (/ISS)

There are 13 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
11 F1M495 (/ISS) F1PGC5 (/ISS) F6Y1A5 (/ISS) F7CUS6 (/ISS) G1L1S3 (/ISS) G1PP42 (/ISS) G1QLJ9 (/ISS) P49259 (/ISS) P49260 (/ISS) Q5R880 (/ISS)
(1 more)
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
1 Q62028 (/IDA)
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
1 Q13018 (/ISS)
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
1 Q13018 (/NAS)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 Q13018 (/IDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 Q62028 (/ISO)
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
1 Q13018 (/NAS)
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
1 Q13018 (/IDA)
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
1 Q62028 (/ISO)
Receptor complex GO:0043235
Any protein complex that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
1 Q13018 (/IDA)
Receptor complex GO:0043235
Any protein complex that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
1 Q62028 (/ISO)
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
1 Q13018 (/IDA)
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
1 Q62028 (/ISO)