The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Hnrnp arginine n-methyltransferase1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1295: Protein arginine N-methyltransferase 7

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein-arginine omega-N symmetric methyltransferase activity GO:0035243
Catalysis of the addition of a second methyl group to methylated peptidyl-arginine. Methylation is on the terminal nitrogen (omega nitrogen) residue that is not already methylated, resulting in symmetrical peptidyl-N(omega),N'(omega)-dimethyled arginine residues.
15 A2AV36 (/ISS) B0X4N1 (/ISS) B3MF31 (/ISS) B3NP10 (/ISS) B4GA28 (/ISS) B4I8G2 (/ISS) B4JWL5 (/ISS) B4KSL6 (/ISS) B4LPB6 (/ISS) B4MNL1 (/ISS)
(5 more)
S-adenosylmethionine-dependent methyltransferase activity GO:0008757
Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a substrate.
1 A2AV36 (/ISS)
Protein-arginine N-methyltransferase activity GO:0016274
Catalysis of the reaction: S-adenosyl-L-methionine + (protein)-arginine = S-adenosyl-L-homocysteine + (protein)-N-methyl-arginine.
1 Q9W1V1 (/ISS)
Protein-arginine omega-N symmetric methyltransferase activity GO:0035243
Catalysis of the addition of a second methyl group to methylated peptidyl-arginine. Methylation is on the terminal nitrogen (omega nitrogen) residue that is not already methylated, resulting in symmetrical peptidyl-N(omega),N'(omega)-dimethyled arginine residues.
1 Q9W1V1 (/IMP)
Histone methyltransferase activity (H4-R3 specific) GO:0044020
Catalysis of the reaction: S-adenosyl-L-methionine + (histone H4)-arginine (position 3) = S-adenosyl-L-homocysteine + (histone H4)-N-methyl-arginine (position 3). This reaction is the addition of a methyl group to arginine at position 3 of histone H4.
1 A2AV36 (/ISS)

There are 7 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Peptidyl-arginine methylation GO:0018216
The addition of a methyl group to an arginine residue in a protein.
15 A2AV36 (/ISS) B0X4N1 (/ISS) B3MF31 (/ISS) B3NP10 (/ISS) B4GA28 (/ISS) B4I8G2 (/ISS) B4JWL5 (/ISS) B4KSL6 (/ISS) B4LPB6 (/ISS) B4MNL1 (/ISS)
(5 more)
Spliceosomal snRNP assembly GO:0000387
The aggregation, arrangement and bonding together of one or more snRNA and multiple protein components to form a ribonucleoprotein complex that is involved in formation of the spliceosome.
1 A2AV36 (/ISS)
Regulation of gene expression by genetic imprinting GO:0006349
Heritable alterations in the activity of a gene that depend on whether it passed through the paternal or the maternal germline, but that are not encoded by DNA itself.
1 A2AV36 (/ISS)
Peptidyl-arginine methylation GO:0018216
The addition of a methyl group to an arginine residue in a protein.
1 Q9W1V1 (/IMP)
Peptidyl-arginine methylation, to asymmetrical-dimethyl arginine GO:0019919
The process of methylation of peptidyl-arginine to form peptidyl-N(omega),N(omega)-dimethyl-L-arginine.
1 Q9W1V1 (/ISS)
Histone arginine methylation GO:0034969
The modification of a histone by addition of a methyl group to an arginine residue.
1 A2AV36 (/ISS)
DNA methylation involved in gamete generation GO:0043046
The covalent transfer of a methyl group to C-5 of cytosine that contributes to the establishment of DNA methylation patterns in the gamete.
1 A2AV36 (/ISS)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 A2AV36 (/ISS)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 A2AV36 (/ISS)