The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Na, k-atpase alpha subunit.
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 369: Sodium/potassium-transporting ATPase subunit beta-...

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Sodium/potassium-exchanging ATPase. [EC: 3.6.3.9]
ATP + H(2)O + Na(+)(In) + K(+)(Out) = ADP + phosphate + Na(+)(Out) + K(+)(In).
  • P-type ATPase that undergoes covalent phosphorylation during the transport cycle.
  • An enzyme from the plasma membrane of animal cells that catalyzes the efflux of three Na(+) and influx of two K(+) per ATP hydrolyzed.
  • It is involved in generating the plasma membrane electrical potential.
  • Formerly EC 3.6.1.37.
10 A0A0J9R6J8 A0A0J9TSR4 A0A0Q5VXC3 A4V0B5 B3NLW8 B4IFP0 M9PDX8 Q1RL12 Q24048 Q7JS69
Transferred entry: 3.6.3.9. [EC: 3.6.1.37]
    1 Q9I9C4
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