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CATH Superfamily 2.60.40.1320

SRS domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
SRS domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1128: SAG-related sequence SRS39

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
IgA-specific serine endopeptidase. [EC: 3.4.21.72]
Cleavage of immunoglobulin A molecules at certain Pro-|-Xaa bonds in the hinge region. No small molecule substrates are known.
  • Species variants differing slightly in specificity are secreted by Gram-negative bacteria Neisseria gonorrhoeae and Haemophilus influenzae.
  • Some other bacterial endopeptidases with similar specificity are of metallotype (see EC 3.4.24.13).
  • Belongs to peptidase family S6.
 143 A0A074SZW7 A0A074SZW7 A0A074SZW7 A0A074SZW7 A0A074SZW7 A0A074SZW7 A0A074SZW7 A0A074SZW7 A0A074SZW7 A0A074SZW7
(133 more...)
DNA-directed DNA polymerase. [EC: 2.7.7.7]
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
  • Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time.
  • Cannot initiate a chain de novo.
  • Requires a primer which may be DNA or RNA.
  • See also EC 2.7.7.49.
 13 A0A0F7UEF7 A0A0F7UEF7 A0A0F7UEF7 A0A0F7UEF7 A0A0F7UEF7 A0A0F7UEF7 A0A0F7UEF7 A0A0F7UEF7 A0A0F7UEF7 A0A0F7UEF7
(3 more...)
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