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CATH Superfamily 2.60.40.1110

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 418: Phosphatase and tensin-like protein

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase. [EC: 3.1.3.67]
Phosphatidylinositol 3,4,5-trisphosphate + H(2)O = phosphatidylinositol 4,5-bisphosphate + phosphate.
  • Does not dephosphorylate inositol 4,5-bisphosphate.
  • This enzyme still works when the 2,3-bis(acyloxy)propyl group is removed, i.e., it hydrolyzes Ins(1,3,4,5)P(4) to Ins(1,4,5)P(3).
 18 A0A061I919 A0A061IBI8 A0A0D9R3M9 D2GZ33 F2Z5H1 F6KD01 G1RNC7 G1SVU9 G3QF16 H2Q280
(8 more...)
Protein-serine/threonine phosphatase. [EC: 3.1.3.16]
[a protein]-serine/threonine phosphate + H(2)O = [a protein]- serine/threonine + phosphate.
  • A group of enzymes removing the serine- or threonine-bound phosphate group from a wide range of phosphoproteins, including a number of enzymes which have been phosphorylated under the action of a kinase (cf. EC 3.1.3.48).
  • The spleen enzyme also acts on phenolic phosphates and phosphamides (cf. EC 3.9.1.1).
 16 A0A0D9R3M9 D2GZ33 F2Z5H1 F6KD01 G1RNC7 G1SVU9 G3QF16 H2Q280 H9YWL4 O08586
(6 more...)
Protein-tyrosine-phosphatase. [EC: 3.1.3.48]
Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.
  • Dephosphorylates O-phosphotyrosine groups in phosphoproteins, such as the products of EC 2.7.10.2.
 16 A0A0D9R3M9 D2GZ33 F2Z5H1 F6KD01 G1RNC7 G1SVU9 G3QF16 H2Q280 H9YWL4 O08586
(6 more...)
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