The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:
"Immunoglobulins
".
FunFam 137068: Ig mu chain C region
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 2 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Antigen binding GO:0003823
Interacting selectively and non-covalently with an antigen, any substance which is capable of inducing a specific immune response and of reacting with the products of that response, the specific antibody or specifically sensitized T-lymphocytes, or both. Binding may counteract the biological activity of the antigen.
|
1 | P04220 (/TAS) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | P01871 (/IPI) |
There are 5 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Adaptive immune response GO:0002250
An immune response mediated by cells expressing specific receptors for antigen produced through a somatic diversification process, and allowing for an enhanced secondary response to subsequent exposures to the same antigen (immunological memory).
|
1 | P01871 (/IDA) |
|
Antibacterial humoral response GO:0019731
An immune response against bacteria mediated through a body fluid. Examples of this process are the antibacterial humoral responses in Mus musculus and Drosophila melanogaster.
|
1 | P01871 (/IDA) |
|
Innate immune response GO:0045087
Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens.
|
1 | P01871 (/IDA) |
|
Defense response to Gram-negative bacterium GO:0050829
Reactions triggered in response to the presence of a Gram-negative bacterium that act to protect the cell or organism.
|
1 | P01871 (/IDA) |
|
Leukocyte migration GO:0050900
The movement of a leukocyte within or between different tissues and organs of the body.
|
1 | P01871 (/TAS) |
There are 7 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
|
2 | P01871 (/IDA) P04220 (/IDA) |
|
Blood microparticle GO:0072562
A phospholipid microvesicle that is derived from any of several cell types, such as platelets, blood cells, endothelial cells, or others, and contains membrane receptors as well as other proteins characteristic of the parental cell. Microparticles are heterogeneous in size, and are characterized as microvesicles free of nucleic acids.
|
2 | P01871 (/IDA) P04220 (/IDA) |
|
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
|
1 | P01871 (/IDA) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
1 | P01871 (/TAS) |
|
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
|
1 | P01871 (/IDA) |
|
Pentameric IgM immunoglobulin complex GO:0071756
A circulating form of IgM consisting of a pentamer of IgM core units with a single J chain polypeptide.
|
1 | P01871 (/IDA) |
|
Hexameric IgM immunoglobulin complex GO:0071757
A circulating form of IgM consisting of a hexamer of IgM core units with a single J chain polypeptide.
|
1 | P01871 (/IDA) |
