The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Immunoglobulins
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 136630: Brother of ihog, isoform E

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Heparin binding GO:0008201
Interacting selectively and non-covalently with heparin, any member of a group of glycosaminoglycans found mainly as an intracellular component of mast cells and which consist predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues.
3 B4JEF2 (/ISS) B4KJW1 (/ISS) B4LRN7 (/ISS)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
3 B4JEF2 (/ISS) B4KJW1 (/ISS) B4LRN7 (/ISS)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
1 A8JUV7 (/IPI)

There are 9 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Smoothened signaling pathway GO:0007224
A series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened.
3 B4JEF2 (/ISS) B4KJW1 (/ISS) B4LRN7 (/ISS)
Compound eye photoreceptor cell differentiation GO:0001751
The process in which a relatively unspecialized cell acquires the specialized features of an eye photoreceptor cell.
2 A8JUV7 (/IGI) Q9W4Y6 (/IGI)
Notch signaling pathway GO:0007219
A series of molecular signals initiated by the binding of an extracellular ligand to the receptor Notch on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
2 A8JUV7 (/IGI) Q9W4Y6 (/IGI)
Smoothened signaling pathway GO:0007224
A series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened.
2 A8JUV7 (/IMP) Q9W4Y6 (/IMP)
Positive regulation of cell proliferation GO:0008284
Any process that activates or increases the rate or extent of cell proliferation.
2 A8JUV7 (/IMP) Q9W4Y6 (/IMP)
Regulation of smoothened signaling pathway GO:0008589
Any process that modulates the frequency, rate or extent of smoothened signaling.
2 A8JUV7 (/IGI) Q9W4Y6 (/IGI)
Cuticle pattern formation GO:0035017
The regionalization process that gives rise to the patterns of cell differentiation in the cuticle.
2 A8JUV7 (/IGI) Q9W4Y6 (/IGI)
Wing disc pattern formation GO:0035222
The process giving rise to the pattern of cell differentiation in the wing imaginal disc.
2 A8JUV7 (/IGI) Q9W4Y6 (/IGI)
Compound eye development GO:0048749
The process whose specific outcome is the progression of the compound eye over time, from its formation to the mature structure. The compound eye is an organ of sight that contains multiple repeating units, often arranged hexagonally. Each unit has its own lens and photoreceptor cell(s) and can generate either a single pixelated image or multiple images, per eye.
2 A8JUV7 (/IGI) Q9W4Y6 (/IGI)

There are 1 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
3 B4JEF2 (/ISS) B4KJW1 (/ISS) B4LRN7 (/ISS)