The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Immunoglobulins
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 136033: Thy-1 membrane glycoprotein

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 11 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
GTPase activator activity GO:0005096
Binds to and increases the activity of a GTPase, an enzyme that catalyzes the hydrolysis of GTP.
8 O62643 (/ISS) P01831 (/ISS) P04216 (/ISS) Q07212 (/ISS) Q3SX33 (/ISS) Q59GA0 (/ISS) Q5R508 (/ISS) Q9WUR5 (/ISS)
GPI anchor binding GO:0034235
Interacting selectively and non-covalently with any glycosylphosphatidylinositol anchor. GPI anchors serve to attach membrane proteins to the lipid bilayer of cell membranes.
8 O62643 (/ISS) P01831 (/ISS) P04216 (/ISS) Q07212 (/ISS) Q3SX33 (/ISS) Q59GA0 (/ISS) Q5R508 (/ISS) Q9WUR5 (/ISS)
Integrin binding GO:0005178
Interacting selectively and non-covalently with an integrin.
2 P01831 (/IMP) P04216 (/IMP)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
2 P01830 (/IPI) P04216 (/IPI)
GTPase activator activity GO:0005096
Binds to and increases the activity of a GTPase, an enzyme that catalyzes the hydrolysis of GTP.
1 P01830 (/IDA)
Integrin binding GO:0005178
Interacting selectively and non-covalently with an integrin.
1 P04216 (/IPI)
Integrin binding GO:0005178
Interacting selectively and non-covalently with an integrin.
1 P01831 (/ISO)
Integrin binding GO:0005178
Interacting selectively and non-covalently with an integrin.
1 P01830 (/ISS)
Enzyme binding GO:0019899
Interacting selectively and non-covalently with any enzyme.
1 P01830 (/IPI)
Protein kinase binding GO:0019901
Interacting selectively and non-covalently with a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate.
1 P01830 (/IPI)
GPI anchor binding GO:0034235
Interacting selectively and non-covalently with any glycosylphosphatidylinositol anchor. GPI anchors serve to attach membrane proteins to the lipid bilayer of cell membranes.
1 P01830 (/IDA)

There are 54 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Angiogenesis GO:0001525
Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels.
8 O62643 (/ISS) P01830 (/ISS) P04216 (/ISS) Q07212 (/ISS) Q3SX33 (/ISS) Q59GA0 (/ISS) Q5R508 (/ISS) Q9WUR5 (/ISS)
Negative regulation of protein kinase activity GO:0006469
Any process that stops, prevents, or reduces the frequency, rate or extent of protein kinase activity.
8 O62643 (/ISS) P01831 (/ISS) P04216 (/ISS) Q07212 (/ISS) Q3SX33 (/ISS) Q59GA0 (/ISS) Q5R508 (/ISS) Q9WUR5 (/ISS)
Cytoskeleton organization GO:0007010
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures.
8 O62643 (/ISS) P01831 (/ISS) P04216 (/ISS) Q07212 (/ISS) Q3SX33 (/ISS) Q59GA0 (/ISS) Q5R508 (/ISS) Q9WUR5 (/ISS)
Single organismal cell-cell adhesion GO:0016337
The attachment of one cell to another cell via adhesion molecules, where both cells are part of the same organism.
8 O62643 (/ISS) P01831 (/ISS) P04216 (/ISS) Q07212 (/ISS) Q3SX33 (/ISS) Q59GA0 (/ISS) Q5R508 (/ISS) Q9WUR5 (/ISS)
Negative regulation of cell migration GO:0030336
Any process that stops, prevents, or reduces the frequency, rate or extent of cell migration.
8 O62643 (/ISS) P01831 (/ISS) P04216 (/ISS) Q07212 (/ISS) Q3SX33 (/ISS) Q59GA0 (/ISS) Q5R508 (/ISS) Q9WUR5 (/ISS)
Positive regulation of GTPase activity GO:0043547
Any process that activates or increases the activity of a GTPase.
8 O62643 (/ISS) P01831 (/ISS) P04216 (/ISS) Q07212 (/ISS) Q3SX33 (/ISS) Q59GA0 (/ISS) Q5R508 (/ISS) Q9WUR5 (/ISS)
Retinal cone cell development GO:0046549
Development of a cone cell, one of the sensory cells in the eye that reacts to the presence of light. Cone cells contain the photopigment iodopsin or cyanopsin and are responsible for photopic (daylight) vision.
8 O62643 (/ISS) P01830 (/ISS) P04216 (/ISS) Q07212 (/ISS) Q3SX33 (/ISS) Q59GA0 (/ISS) Q5R508 (/ISS) Q9WUR5 (/ISS)
Focal adhesion assembly GO:0048041
The aggregation and bonding together of a set of components to form a focal adhesion, a complex of intracellular signaling and structural proteins that provides a structural link between the internal actin cytoskeleton and the ECM, and also function as a locus of signal transduction activity.
8 O62643 (/ISS) P01831 (/ISS) P04216 (/ISS) Q07212 (/ISS) Q3SX33 (/ISS) Q59GA0 (/ISS) Q5R508 (/ISS) Q9WUR5 (/ISS)
Negative regulation of axonogenesis GO:0050771
Any process that stops, prevents, or reduces the frequency, rate or extent of axonogenesis.
8 O62643 (/ISS) P01831 (/ISS) P04216 (/ISS) Q07212 (/ISS) Q3SX33 (/ISS) Q59GA0 (/ISS) Q5R508 (/ISS) Q9WUR5 (/ISS)
T cell receptor signaling pathway GO:0050852
A series of molecular signals initiated by the cross-linking of an antigen receptor on a T cell.
8 O62643 (/ISS) P01831 (/ISS) P04216 (/ISS) Q07212 (/ISS) Q3SX33 (/ISS) Q59GA0 (/ISS) Q5R508 (/ISS) Q9WUR5 (/ISS)
Negative regulation of T cell receptor signaling pathway GO:0050860
Any process that stops, prevents, or reduces the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a T cell.
8 O62643 (/ISS) P01830 (/ISS) P04216 (/ISS) Q07212 (/ISS) Q3SX33 (/ISS) Q59GA0 (/ISS) Q5R508 (/ISS) Q9WUR5 (/ISS)
Positive regulation of T cell activation GO:0050870
Any process that activates or increases the frequency, rate or extent of T cell activation.
8 O62643 (/ISS) P01831 (/ISS) P04216 (/ISS) Q07212 (/ISS) Q3SX33 (/ISS) Q59GA0 (/ISS) Q5R508 (/ISS) Q9WUR5 (/ISS)
Positive regulation of release of sequestered calcium ion into cytosol GO:0051281
Any process that activates or increases the frequency, rate or extent of the release into the cytosolic compartment of calcium ions sequestered in the endoplasmic reticulum or mitochondria.
8 O62643 (/ISS) P01831 (/ISS) P04216 (/ISS) Q07212 (/ISS) Q3SX33 (/ISS) Q59GA0 (/ISS) Q5R508 (/ISS) Q9WUR5 (/ISS)
Integrin-mediated signaling pathway GO:0007229
A series of molecular signals initiated by the binding of extracellular ligand to an integrin on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
2 P01831 (/IMP) P04216 (/IMP)
Cell-cell signaling GO:0007267
Any process that mediates the transfer of information from one cell to another. This process includes signal transduction in the receiving cell and, where applicable, release of a ligand and any processes that actively facilitate its transport and presentation to the receiving cell. Examples include signaling via soluble ligands, via cell adhesion molecules and via gap junctions.
2 P01830 (/IDA) P01831 (/IDA)
Receptor clustering GO:0043113
The receptor metabolic process that results in grouping of a set of receptors at a cellular location, often to amplify the sensitivity of a signaling response.
2 P01831 (/ISS) P04216 (/ISS)
Positive regulation of focal adhesion assembly GO:0051894
Any process that activates or increases the frequency, rate or extent of focal adhesion assembly, the establishment and maturation of focal adhesions.
2 P01831 (/IMP) P04216 (/IMP)
Negative regulation of protein tyrosine kinase activity GO:0061099
Any process that decreases the rate, frequency, or extent of protein tyrosine kinase activity.
2 P01831 (/ISS) P04216 (/ISS)
Negative regulation of neuron projection regeneration GO:0070571
Any process that stops, prevents, or reduces the frequency, rate or extent of neuron projection regeneration, the regrowth of neuronal processes such as axons or dendrites following their loss or damage.
2 P01830 (/IMP) P01831 (/IMP)
Regulation of Rho-dependent protein serine/threonine kinase activity GO:2000298
Any process that modulates the frequency, rate or extent of Rho-dependent protein serine/threonine kinase activity.
2 P01830 (/ISS) P04216 (/ISS)
Angiogenesis GO:0001525
Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels.
1 P01831 (/IDA)
Regulation of cell-matrix adhesion GO:0001952
Any process that modulates the frequency, rate or extent of attachment of a cell to the extracellular matrix.
1 P04216 (/IMP)
Regulation of cell-matrix adhesion GO:0001952
Any process that modulates the frequency, rate or extent of attachment of a cell to the extracellular matrix.
1 P01831 (/ISO)
Positive regulation of cellular extravasation GO:0002693
Any process that activates or increases the frequency, rate, or extent of cellular extravasation.
1 P04216 (/IDA)
Positive regulation of cellular extravasation GO:0002693
Any process that activates or increases the frequency, rate, or extent of cellular extravasation.
1 P01831 (/ISO)
Negative regulation of protein kinase activity GO:0006469
Any process that stops, prevents, or reduces the frequency, rate or extent of protein kinase activity.
1 P01830 (/IDA)
C-terminal protein lipidation GO:0006501
The covalent attachment of a lipid group to the carboxy terminus of a protein.
1 P04216 (/TAS)
Cytoskeleton organization GO:0007010
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures.
1 P01830 (/IDA)
Integrin-mediated signaling pathway GO:0007229
A series of molecular signals initiated by the binding of extracellular ligand to an integrin on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
1 P01831 (/ISO)
Integrin-mediated signaling pathway GO:0007229
A series of molecular signals initiated by the binding of extracellular ligand to an integrin on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
1 P01830 (/ISS)
Cell-cell signaling GO:0007267
Any process that mediates the transfer of information from one cell to another. This process includes signal transduction in the receiving cell and, where applicable, release of a ligand and any processes that actively facilitate its transport and presentation to the receiving cell. Examples include signaling via soluble ligands, via cell adhesion molecules and via gap junctions.
1 P04216 (/ISS)
Single organismal cell-cell adhesion GO:0016337
The attachment of one cell to another cell via adhesion molecules, where both cells are part of the same organism.
1 P01830 (/IMP)
Negative regulation of cell migration GO:0030336
Any process that stops, prevents, or reduces the frequency, rate or extent of cell migration.
1 P01830 (/IDA)
Positive regulation of heterotypic cell-cell adhesion GO:0034116
Any process that activates or increases the frequency, rate, or extent of heterotypic cell-cell adhesion.
1 P04216 (/IDA)
Positive regulation of heterotypic cell-cell adhesion GO:0034116
Any process that activates or increases the frequency, rate, or extent of heterotypic cell-cell adhesion.
1 P01831 (/ISO)
Negative regulation of apoptotic process GO:0043066
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.
1 P01830 (/TAS)
Receptor clustering GO:0043113
The receptor metabolic process that results in grouping of a set of receptors at a cellular location, often to amplify the sensitivity of a signaling response.
1 P01830 (/IDA)
Positive regulation of GTPase activity GO:0043547
Any process that activates or increases the activity of a GTPase.
1 P01830 (/IDA)
Mast cell activation GO:0045576
The change in morphology and behavior of a mast cell resulting from exposure to a cytokine, chemokine, soluble factor, or to (at least in mammals) an antigen which the mast cell has specifically bound via IgE bound to Fc-epsilonRI receptors.
1 P01830 (/NAS)
Retinal cone cell development GO:0046549
Development of a cone cell, one of the sensory cells in the eye that reacts to the presence of light. Cone cells contain the photopigment iodopsin or cyanopsin and are responsible for photopic (daylight) vision.
1 P01831 (/IMP)
Protein autophosphorylation GO:0046777
The phosphorylation by a protein of one or more of its own amino acid residues (cis-autophosphorylation), or residues on an identical protein (trans-autophosphorylation).
1 P01830 (/IDA)
Focal adhesion assembly GO:0048041
The aggregation and bonding together of a set of components to form a focal adhesion, a complex of intracellular signaling and structural proteins that provides a structural link between the internal actin cytoskeleton and the ECM, and also function as a locus of signal transduction activity.
1 P01830 (/IDA)
Negative regulation of fibroblast proliferation GO:0048147
Any process that stops, prevents, or reduces the frequency, rate or extent of multiplication or reproduction of fibroblast cells.
1 P01830 (/NAS)
Positive regulation of peptidyl-tyrosine phosphorylation GO:0050731
Any process that activates or increases the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine.
1 P01830 (/NAS)
Negative regulation of axonogenesis GO:0050771
Any process that stops, prevents, or reduces the frequency, rate or extent of axonogenesis.
1 P01830 (/IDA)
T cell receptor signaling pathway GO:0050852
A series of molecular signals initiated by the cross-linking of an antigen receptor on a T cell.
1 P01830 (/IMP)
Negative regulation of T cell receptor signaling pathway GO:0050860
Any process that stops, prevents, or reduces the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a T cell.
1 P01831 (/IDA)
Positive regulation of T cell activation GO:0050870
Any process that activates or increases the frequency, rate or extent of T cell activation.
1 P01830 (/IDA)
Positive regulation of release of sequestered calcium ion into cytosol GO:0051281
Any process that activates or increases the frequency, rate or extent of the release into the cytosolic compartment of calcium ions sequestered in the endoplasmic reticulum or mitochondria.
1 P01830 (/IDA)
Positive regulation of focal adhesion assembly GO:0051894
Any process that activates or increases the frequency, rate or extent of focal adhesion assembly, the establishment and maturation of focal adhesions.
1 P01831 (/ISO)
Positive regulation of focal adhesion assembly GO:0051894
Any process that activates or increases the frequency, rate or extent of focal adhesion assembly, the establishment and maturation of focal adhesions.
1 P01830 (/ISS)
Negative regulation of protein tyrosine kinase activity GO:0061099
Any process that decreases the rate, frequency, or extent of protein tyrosine kinase activity.
1 P01830 (/IDA)
Negative regulation of neuron projection regeneration GO:0070571
Any process that stops, prevents, or reduces the frequency, rate or extent of neuron projection regeneration, the regrowth of neuronal processes such as axons or dendrites following their loss or damage.
1 P04216 (/ISS)
Regulation of Rho-dependent protein serine/threonine kinase activity GO:2000298
Any process that modulates the frequency, rate or extent of Rho-dependent protein serine/threonine kinase activity.
1 P01831 (/IDA)

There are 36 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
8 O62643 (/ISS) P01831 (/ISS) P04216 (/ISS) Q07212 (/ISS) Q3SX33 (/ISS) Q59GA0 (/ISS) Q5R508 (/ISS) Q9WUR5 (/ISS)
External side of plasma membrane GO:0009897
The leaflet of the plasma membrane that faces away from the cytoplasm and any proteins embedded or anchored in it or attached to its surface.
8 O62643 (/ISS) P01830 (/ISS) P04216 (/ISS) Q07212 (/ISS) Q3SX33 (/ISS) Q59GA0 (/ISS) Q5R508 (/ISS) Q9WUR5 (/ISS)
Growth cone GO:0030426
The migrating motile tip of a growing nerve cell axon or dendrite.
8 O62643 (/ISS) P01831 (/ISS) P04216 (/ISS) Q07212 (/ISS) Q3SX33 (/ISS) Q59GA0 (/ISS) Q5R508 (/ISS) Q9WUR5 (/ISS)
Cell GO:0005623
The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
2 E1C6J9 (/IDA) Q07212 (/IDA)
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
2 P01830 (/IDA) P04216 (/IDA)
Axolemma GO:0030673
The portion of the plasma membrane surrounding an axon; it is a specialized trilaminar random mosaic of protein molecules floating within a fluid matrix of highly mobile phospholipid molecules, 7-8 nm in thickness.
2 P01831 (/ISS) P04216 (/ISS)
Dendrite membrane GO:0032590
The portion of the plasma membrane surrounding a dendrite.
2 P01831 (/ISS) P04216 (/ISS)
Neuronal cell body membrane GO:0032809
The plasma membrane of a neuron cell body - excludes the plasma membrane of cell projections such as axons and dendrites.
2 P01831 (/ISS) P04216 (/ISS)
Membrane raft GO:0045121
Any of the small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes. Small rafts can sometimes be stabilized to form larger platforms through protein-protein and protein-lipid interactions.
2 P01830 (/IDA) P01831 (/IDA)
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
1 P04216 (/TAS)
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
1 P04216 (/IDA)
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
1 P01831 (/ISO)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 P01830 (/IDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 P01830 (/IDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 P04216 (/NAS)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 P04216 (/TAS)
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
1 P04216 (/TAS)
Focal adhesion GO:0005925
Small region on the surface of a cell that anchors the cell to the extracellular matrix and that forms a point of termination of actin filaments.
1 P04216 (/IDA)
Focal adhesion GO:0005925
Small region on the surface of a cell that anchors the cell to the extracellular matrix and that forms a point of termination of actin filaments.
1 P01831 (/ISO)
External side of plasma membrane GO:0009897
The leaflet of the plasma membrane that faces away from the cytoplasm and any proteins embedded or anchored in it or attached to its surface.
1 P01831 (/IDA)
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
1 P01831 (/ISO)
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
1 P01831 (/ISS)
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
1 P01830 (/TAS)
Apical plasma membrane GO:0016324
The region of the plasma membrane located at the apical end of the cell.
1 P04216 (/IDA)
Apical plasma membrane GO:0016324
The region of the plasma membrane located at the apical end of the cell.
1 P01831 (/ISO)
Dendrite GO:0030425
A neuron projection that has a short, tapering, often branched, morphology, receives and integrates signals from other neurons or from sensory stimuli, and conducts a nerve impulse towards the axon or the cell body. In most neurons, the impulse is conveyed from dendrites to axon via the cell body, but in some types of unipolar neuron, the impulse does not travel via the cell body.
1 P01831 (/IDA)
Growth cone GO:0030426
The migrating motile tip of a growing nerve cell axon or dendrite.
1 P01830 (/IDA)
Axolemma GO:0030673
The portion of the plasma membrane surrounding an axon; it is a specialized trilaminar random mosaic of protein molecules floating within a fluid matrix of highly mobile phospholipid molecules, 7-8 nm in thickness.
1 P01830 (/IDA)
Anchored component of external side of plasma membrane GO:0031362
The component of the plasma membrane consisting of the gene products that are tethered to the external side of the membrane only by a covalently attached anchor, such as a lipid group embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping.
1 P01831 (/IDA)
Dendrite membrane GO:0032590
The portion of the plasma membrane surrounding a dendrite.
1 P01830 (/IDA)
Neuronal cell body membrane GO:0032809
The plasma membrane of a neuron cell body - excludes the plasma membrane of cell projections such as axons and dendrites.
1 P01830 (/IDA)
Myelin sheath GO:0043209
An electrically insulating fatty layer that surrounds the axons of many neurons. It is an outgrowth of glial cells: Schwann cells supply the myelin for peripheral neurons while oligodendrocytes supply it to those of the central nervous system.
1 P01831 (/IDA)
Membrane raft GO:0045121
Any of the small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes. Small rafts can sometimes be stabilized to form larger platforms through protein-protein and protein-lipid interactions.
1 P04216 (/NAS)
Anchored component of plasma membrane GO:0046658
The component of the plasma membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group, that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping.
1 P01830 (/IDA)
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
1 P04216 (/IDA)
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
1 P01831 (/ISO)