The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:
"Immunoglobulins
".
FunFam 133260: CD276 antigen isoform 1
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 4 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Receptor binding GO:0005102
Interacting selectively and non-covalently with one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
|
2 | Q5ZPR3 (/NAS) Q5ZPR3 (/NAS) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
2 | Q5ZPR3 (/IPI) Q5ZPR3 (/IPI) |
|
Receptor binding GO:0005102
Interacting selectively and non-covalently with one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
|
1 | Q8VE98 (/IDA) |
|
Receptor binding GO:0005102
Interacting selectively and non-covalently with one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
|
1 | Q8VE98 (/IMP) |
There are 20 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Immune response GO:0006955
Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat.
|
2 | Q5ZPR3 (/NAS) Q5ZPR3 (/NAS) |
|
Cell proliferation GO:0008283
The multiplication or reproduction of cells, resulting in the expansion of a cell population.
|
2 | Q5ZPR3 (/NAS) Q5ZPR3 (/NAS) |
|
Positive regulation of T cell proliferation GO:0042102
Any process that activates or increases the rate or extent of T cell proliferation.
|
2 | Q5ZPR3 (/IDA) Q5ZPR3 (/IDA) |
|
T cell activation GO:0042110
The change in morphology and behavior of a mature or immature T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.
|
2 | Q5ZPR3 (/IDA) Q5ZPR3 (/IDA) |
|
Positive regulation of interferon-gamma biosynthetic process GO:0045078
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interferon-gamma.
|
2 | Q5ZPR3 (/IDA) Q5ZPR3 (/IDA) |
|
Regulation of immune response GO:0050776
Any process that modulates the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.
|
2 | Q5ZPR3 (/NAS) Q5ZPR3 (/NAS) |
|
Positive regulation of bone mineralization GO:0030501
Any process that activates or increases the frequency, rate or extent of bone mineralization.
|
1 | Q8VE98 (/IMP) |
|
Positive regulation of T cell proliferation GO:0042102
Any process that activates or increases the rate or extent of T cell proliferation.
|
1 | Q8VE98 (/IMP) |
|
Positive regulation of T cell proliferation GO:0042102
Any process that activates or increases the rate or extent of T cell proliferation.
|
1 | Q8VE98 (/ISO) |
|
T cell activation GO:0042110
The change in morphology and behavior of a mature or immature T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.
|
1 | Q8VE98 (/ISO) |
|
Negative regulation of T cell proliferation GO:0042130
Any process that stops, prevents or reduces the rate or extent of T cell proliferation.
|
1 | Q8VE98 (/IDA) |
|
Negative regulation of T cell proliferation GO:0042130
Any process that stops, prevents or reduces the rate or extent of T cell proliferation.
|
1 | Q8VE98 (/IMP) |
|
Negative regulation of interferon-gamma biosynthetic process GO:0045077
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interferon-gamma.
|
1 | Q8VE98 (/IDA) |
|
Negative regulation of interferon-gamma biosynthetic process GO:0045077
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interferon-gamma.
|
1 | Q8VE98 (/IMP) |
|
Positive regulation of interferon-gamma biosynthetic process GO:0045078
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interferon-gamma.
|
1 | Q8VE98 (/ISO) |
|
Negative regulation of interleukin-2 biosynthetic process GO:0045085
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-2.
|
1 | Q8VE98 (/IDA) |
|
Positive regulation of osteoblast differentiation GO:0045669
Any process that activates or increases the frequency, rate or extent of osteoblast differentiation.
|
1 | Q8VE98 (/IMP) |
|
Negative regulation of inflammatory response GO:0050728
Any process that stops, prevents, or reduces the frequency, rate or extent of the inflammatory response.
|
1 | Q8VE98 (/IMP) |
|
Regulation of immune response GO:0050776
Any process that modulates the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.
|
1 | Q8VE98 (/IMP) |
|
Positive regulation of interleukin-2 secretion GO:1900042
Any process that activates or increases the frequency, rate or extent of interleukin-2 secretion.
|
1 | Q8VE98 (/IMP) |
There are 5 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
External side of plasma membrane GO:0009897
The leaflet of the plasma membrane that faces away from the cytoplasm and any proteins embedded or anchored in it or attached to its surface.
|
2 | Q5ZPR3 (/NAS) Q5ZPR3 (/NAS) |
|
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
2 | Q5ZPR3 (/NAS) Q5ZPR3 (/NAS) |
|
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
|
2 | Q5ZPR3 (/IDA) Q5ZPR3 (/IDA) |
|
External side of plasma membrane GO:0009897
The leaflet of the plasma membrane that faces away from the cytoplasm and any proteins embedded or anchored in it or attached to its surface.
|
1 | Q8VE98 (/IDA) |
|
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
|
1 | Q8VE98 (/ISO) |