The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Immunoglobulins
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 132506: GH11839

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 1 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
4 M9PCI6 (/IPI) Q9BN17 (/IPI) Q9VQW1 (/IPI) Q9VQW7 (/IPI)

There are 33 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Sensory organ development GO:0007423
The process whose specific outcome is the progression of sensory organs over time, from its formation to the mature structure.
6 A0A023GPK8 (/IMP) M9NCR3 (/IMP) M9PCI6 (/IMP) Q9BN17 (/IMP) Q9VQW1 (/IMP) Q9VQW7 (/IMP)
Compound eye morphogenesis GO:0001745
The morphogenetic process in which the anatomical structures of the compound eye are generated and organized. The adult compound eye is a precise assembly of 700-800 ommatidia. Each ommatidium is composed of 20 cells, identified by cell type and position. An example of compound eye morphogenesis is found in Drosophila melanogaster.
3 A0A023GPK8 (/IMP) M9NCR3 (/IMP) Q9VQW1 (/IMP)
Morphogenesis of an epithelium GO:0002009
The process in which the anatomical structures of epithelia are generated and organized. An epithelium consists of closely packed cells arranged in one or more layers, that covers the outer surfaces of the body or lines any internal cavity or tube.
3 M9PCI6 (/IMP) Q9BN17 (/IMP) Q9VQW7 (/IMP)
Inter-male aggressive behavior GO:0002121
Aggressive behavior based on competition between males of the same species over access to resources such as females, dominance, status, etc. and characterized by noise, threats, and is often less injurious.
3 M9PCI6 (/IMP) Q9BN17 (/IMP) Q9VQW7 (/IMP)
Homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156
The attachment of a plasma membrane adhesion molecule in one cell to an identical molecule in an adjacent cell.
3 M9PCI6 (/IDA) Q9BN17 (/IDA) Q9VQW7 (/IDA)
Homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156
The attachment of a plasma membrane adhesion molecule in one cell to an identical molecule in an adjacent cell.
3 M9PCI6 (/IMP) Q9BN17 (/IMP) Q9VQW7 (/IMP)
Epidermal growth factor receptor signaling pathway GO:0007173
A series of molecular signals initiated by binding of a ligand to the tyrosine kinase receptor EGFR (ERBB1) on the surface of a cell. The pathway ends with regulation of a downstream cellular process, e.g. transcription.
3 M9PCI6 (/IMP) Q9BN17 (/IMP) Q9VQW7 (/IMP)
Epidermal growth factor receptor signaling pathway GO:0007173
A series of molecular signals initiated by binding of a ligand to the tyrosine kinase receptor EGFR (ERBB1) on the surface of a cell. The pathway ends with regulation of a downstream cellular process, e.g. transcription.
3 M9PCI6 (/IPI) Q9BN17 (/IPI) Q9VQW7 (/IPI)
Dorsal closure GO:0007391
The process during Drosophila embryogenesis whereby the ectodermal cells of the lateral epithelium stretch in a coordinated fashion to internalize the amnioserosa cells and close the embryo dorsally.
3 M9PCI6 (/IMP) Q9BN17 (/IMP) Q9VQW7 (/IMP)
Imaginal disc-derived wing morphogenesis GO:0007476
The process in which the anatomical structures of the imaginal disc-derived wing are generated and organized. The wing is an appendage modified for flying.
3 M9PCI6 (/IMP) Q9BN17 (/IMP) Q9VQW7 (/IMP)
Regulation of cell shape GO:0008360
Any process that modulates the surface configuration of a cell.
3 M9PCI6 (/IMP) Q9BN17 (/IMP) Q9VQW7 (/IMP)
Mushroom body development GO:0016319
The process whose specific outcome is the progression of the mushroom body over time, from its formation to the mature structure. The mushroom body is composed of the prominent neuropil structures of the insect central brain, thought to be crucial for olfactory associated learning. These consist mainly of a bulbous calyx and tightly packaged arrays of thin parallel fibers of the Kenyon cells.
3 M9PCI6 (/IMP) Q9BN17 (/IMP) Q9VQW7 (/IMP)
Single organismal cell-cell adhesion GO:0016337
The attachment of one cell to another cell via adhesion molecules, where both cells are part of the same organism.
3 M9PCI6 (/IMP) Q9BN17 (/IMP) Q9VQW7 (/IMP)
Contractile actin filament bundle assembly GO:0030038
Assembly of actin filament bundles in which the filaments are loosely packed (approximately 30-60 nm apart) and arranged with opposing polarities; the loose packing allows myosin (usually myosin-II) to enter the bundle.
3 M9PCI6 (/IMP) Q9BN17 (/IMP) Q9VQW7 (/IMP)
Regulation of actin cytoskeleton organization GO:0032956
Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins.
3 M9PCI6 (/IMP) Q9BN17 (/IMP) Q9VQW7 (/IMP)
Adult chitin-based cuticle pattern formation GO:0035018
The process that gives rise to the patterns of cell differentiation that will arise in the chitin-based adult cuticle. An example of this process is adult chitin-based cuticle pattern formation in Drosophila melanogaster.
3 A0A023GPK8 (/IMP) M9NCR3 (/IMP) Q9VQW1 (/IMP)
Branch fusion, open tracheal system GO:0035147
Fusing of specific tracheal branches in an open tracheal system to branches from neighboring hemisegments to form a continuous tracheal network. Branch fusion is mediated by individual cells at the tip of each branch, which contact a similar cell and undergo a coordinated series of morphogenetic events that create a bicellular fusion joint.
3 M9PCI6 (/IMP) Q9BN17 (/IMP) Q9VQW7 (/IMP)
Negative regulation of fusion cell fate specification GO:0035157
Any process that restricts, stops or prevents a cell from adopting a fusion cell fate. Once the terminal and fusion fates have been correctly induced, inhibitory feedback loops prevent the remaining branch cells from assuming similar fates.
3 M9PCI6 (/IMP) Q9BN17 (/IMP) Q9VQW7 (/IMP)
Regulation of hippo signaling GO:0035330
Any process that modulates the frequency, rate or extent of hippo signaling.
3 M9PCI6 (/IPI) Q9BN17 (/IPI) Q9VQW7 (/IPI)
Negative regulation of hippo signaling GO:0035331
Any process that stops, prevents, or reduces the frequency, rate or extent of hippo signaling.
3 M9PCI6 (/IGI) Q9BN17 (/IGI) Q9VQW7 (/IGI)
Negative regulation of epidermal growth factor receptor signaling pathway GO:0042059
Any process that stops, prevents, or reduces the frequency, rate or extent of epidermal growth factor receptor signaling pathway activity.
3 M9PCI6 (/IGI) Q9BN17 (/IGI) Q9VQW7 (/IGI)
Negative regulation of epidermal growth factor receptor signaling pathway GO:0042059
Any process that stops, prevents, or reduces the frequency, rate or extent of epidermal growth factor receptor signaling pathway activity.
3 M9PCI6 (/IMP) Q9BN17 (/IMP) Q9VQW7 (/IMP)
Negative regulation of epidermal growth factor receptor signaling pathway GO:0042059
Any process that stops, prevents, or reduces the frequency, rate or extent of epidermal growth factor receptor signaling pathway activity.
3 M9PCI6 (/NAS) Q9BN17 (/NAS) Q9VQW7 (/NAS)
Wound healing GO:0042060
The series of events that restore integrity to a damaged tissue, following an injury.
3 M9PCI6 (/IMP) Q9BN17 (/IMP) Q9VQW7 (/IMP)
Lateral inhibition GO:0046331
Signaling between cells of equivalent developmental potential that results in these cells adopting different developmental fates. An example is the suppression by cells with a particular fate of the adoption of the same fate by surrounding cells.
3 M9PCI6 (/IMP) Q9BN17 (/IMP) Q9VQW7 (/IMP)
Negative regulation of organ growth GO:0046621
Any process that stops, prevents, or reduces the frequency, rate or extent of growth of an organ of an organism.
3 M9PCI6 (/IMP) Q9BN17 (/IMP) Q9VQW7 (/IMP)
Dorsal appendage formation GO:0046843
Establishment of the dorsal filaments, elaborate specializations of the chorion that protrude from the anterior end of the egg and facilitate embryonic respiration.
3 M9PCI6 (/IMP) Q9BN17 (/IMP) Q9VQW7 (/IMP)
Muscle organ morphogenesis GO:0048644
The process in which the anatomical structures of muscle are generated and organized.
3 M9PCI6 (/IMP) Q9BN17 (/IMP) Q9VQW7 (/IMP)
Negative regulation of neurogenesis GO:0050768
Any process that stops, prevents, or reduces the frequency, rate or extent of neurogenesis, the origin and formation of neurons.
3 M9PCI6 (/IMP) Q9BN17 (/IMP) Q9VQW7 (/IMP)
Regulation of actin cytoskeleton organization by cell-cell adhesion GO:0090138
Any cell-cell adhesion process that modulates the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins.
3 M9PCI6 (/IMP) Q9BN17 (/IMP) Q9VQW7 (/IMP)
Ommatidial rotation GO:0016318
The process in which photoreceptors are arranged in ommatidia in the dorsal and ventral fields to be mirror images. The polarity is established in the imaginal discs concurrently with cell fate specification.
2 A0A023GPK8 (/IGI) Q9VQW7 (/IGI)
Ommatidial rotation GO:0016318
The process in which photoreceptors are arranged in ommatidia in the dorsal and ventral fields to be mirror images. The polarity is established in the imaginal discs concurrently with cell fate specification.
2 A0A023GPK8 (/IMP) Q9VQW7 (/IMP)
Cuticle development GO:0042335
The chemical reactions and pathways resulting in the formation of a cuticle, the outer layer of some animals and plants, which acts to prevent water loss.
1 Q9BN17 (/IGI)

There are 5 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
3 M9PCI6 (/IDA) Q9BN17 (/IDA) Q9VQW7 (/IDA)
Adherens junction GO:0005912
A cell junction at which anchoring proteins (cadherins or integrins) extend through the plasma membrane and are attached to actin filaments.
3 M9PCI6 (/IDA) Q9BN17 (/IDA) Q9VQW7 (/IDA)
Cell-cell adherens junction GO:0005913
An adherens junction which connects a cell to another cell.
3 M9PCI6 (/IDA) Q9BN17 (/IDA) Q9VQW7 (/IDA)
Cell cortex GO:0005938
The region of a cell that lies just beneath the plasma membrane and often, but not always, contains a network of actin filaments and associated proteins.
3 M9PCI6 (/IDA) Q9BN17 (/IDA) Q9VQW7 (/IDA)
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
3 M9PCI6 (/ISM) Q9BN17 (/ISM) Q9VQW7 (/ISM)