CATH Superfamily 2.60.200.20
The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.
FunFam 8223: Kinesin-like protein KIF28P
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 12 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Microtubule motor activity GO:0003777
Catalysis of movement along a microtubule, coupled to the hydrolysis of a nucleoside triphosphate (usually ATP).
|
8 | A0A0B4KFR5 (/ISS) A0A0B4KG24 (/ISS) A0A0B4LGK5 (/ISS) A1ZA18 (/ISS) A4UZI0 (/ISS) Q7JMZ1 (/ISS) Q9H1H9 (/ISS) Q9VIP4 (/ISS) |
Microtubule motor activity GO:0003777
Catalysis of movement along a microtubule, coupled to the hydrolysis of a nucleoside triphosphate (usually ATP).
|
6 | A0A0B4KFR5 (/IDA) A0A0B4KG24 (/IDA) A0A0B4LGK5 (/IDA) A1ZA18 (/IDA) A4UZI0 (/IDA) Q9EQW7 (/IDA) |
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
|
5 | A0A0B4KFR5 (/IDA) A0A0B4KG24 (/IDA) A0A0B4LGK5 (/IDA) A1ZA18 (/IDA) A4UZI0 (/IDA) |
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
3 | Q9EQW7 (/IPI) Q9H1H9 (/IPI) Q9NQT8 (/IPI) |
Chromatin binding GO:0003682
Interacting selectively and non-covalently with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.
|
2 | Q7JMZ1 (/TAS) Q9VIP4 (/TAS) |
Protein phosphatase 1 binding GO:0008157
Interacting selectively and non-covalently with the enzyme protein phosphatase 1.
|
2 | Q7JMZ1 (/IPI) Q9VIP4 (/IPI) |
ATP-dependent microtubule motor activity, plus-end-directed GO:0008574
Catalysis of movement along a microtubule toward the plus end, coupled to the hydrolysis of ATP.
|
2 | Q7JMZ1 (/TAS) Q9VIP4 (/TAS) |
Microtubule motor activity GO:0003777
Catalysis of movement along a microtubule, coupled to the hydrolysis of a nucleoside triphosphate (usually ATP).
|
1 | Q9NQT8 (/NAS) |
Protein kinase binding GO:0019901
Interacting selectively and non-covalently with a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate.
|
1 | Q9NQT8 (/IPI) |
Protein kinase binding GO:0019901
Interacting selectively and non-covalently with a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate.
|
1 | E9Q4K7 (/ISO) |
14-3-3 protein binding GO:0071889
Interacting selectively and non-covalently with a 14-3-3 protein. A 14-3-3 protein is any of a large family of approximately 30kDa acidic proteins which exist primarily as homo- and heterodimers within all eukaryotic cells, and have been implicated in the modulation of distinct biological processes by binding to specific phosphorylated sites on diverse target proteins, thereby forcing conformational changes or influencing interactions between their targets and other molecules. Each 14-3-3 protein sequence can be roughly divided into three sections: a divergent amino terminus, the conserved core region and a divergent carboxyl terminus. The conserved middle core region of the 14-3-3s encodes an amphipathic groove that forms the main functional domain, a cradle for interacting with client proteins.
|
1 | Q9NQT8 (/IDA) |
14-3-3 protein binding GO:0071889
Interacting selectively and non-covalently with a 14-3-3 protein. A 14-3-3 protein is any of a large family of approximately 30kDa acidic proteins which exist primarily as homo- and heterodimers within all eukaryotic cells, and have been implicated in the modulation of distinct biological processes by binding to specific phosphorylated sites on diverse target proteins, thereby forcing conformational changes or influencing interactions between their targets and other molecules. Each 14-3-3 protein sequence can be roughly divided into three sections: a divergent amino terminus, the conserved core region and a divergent carboxyl terminus. The conserved middle core region of the 14-3-3s encodes an amphipathic groove that forms the main functional domain, a cradle for interacting with client proteins.
|
1 | E9Q4K7 (/ISO) |
There are 40 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Microtubule-based movement GO:0007018
A microtubule-based process that results in the movement of organelles, other microtubules, or other cellular components. Examples include motor-driven movement along microtubules and movement driven by polymerization or depolymerization of microtubules.
|
7 | A0A0B4KFR5 (/ISS) A0A0B4KG24 (/ISS) A0A0B4LGK5 (/ISS) A1ZA18 (/ISS) A4UZI0 (/ISS) Q7JMZ1 (/ISS) Q9VIP4 (/ISS) |
Regulation of synapse structure or activity GO:0050803
Any process that modulates the physical form or the activity of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell).
|
5 | A0A0B4KFR5 (/IMP) A0A0B4KG24 (/IMP) A0A0B4LGK5 (/IMP) A1ZA18 (/IMP) A4UZI0 (/IMP) |
Establishment of spindle orientation GO:0051294
Any process that set the alignment of spindle relative to other cellular structures.
|
5 | A0A0B4KFR5 (/IMP) A0A0B4KG24 (/IMP) A0A0B4LGK5 (/IMP) A1ZA18 (/IMP) A4UZI0 (/IMP) |
Mitotic sister chromatid segregation GO:0000070
The cell cycle process in which replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the mitotic cell cycle. Each replicated chromosome, composed of two sister chromatids, aligns at the cell equator, paired with its homologous partner. One homolog of each morphologic type goes into each of the resulting chromosome sets.
|
2 | Q7JMZ1 (/IMP) Q9VIP4 (/IMP) |
Mitochondrion organization GO:0007005
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitochondrion; includes mitochondrial morphogenesis and distribution, and replication of the mitochondrial genome as well as synthesis of new mitochondrial components.
|
2 | B7ZC32 (/ISS) D3YXS5 (/ISS) |
Chromosome segregation GO:0007059
The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. In eukaryotes, chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles.
|
2 | Q7JMZ1 (/TAS) Q9VIP4 (/TAS) |
Mitotic chromosome condensation GO:0007076
The cell cycle process in which chromatin structure is compacted prior to and during mitosis in eukaryotic cells.
|
2 | Q7JMZ1 (/IMP) Q9VIP4 (/IMP) |
Ovarian follicle cell development GO:0030707
The process that occurs during oogenesis involving the ovarian follicle cells, somatic cells which surround the germ cells of an ovary. An example of this is found in Drosophila melanogaster.
|
2 | Q7JMZ1 (/IMP) Q9VIP4 (/IMP) |
Mitotic cell cycle, embryonic GO:0045448
The eukaryotic cell cycle in which a cell is duplicated without changing ploidy, occurring in the embryo.
|
2 | Q7JMZ1 (/IMP) Q9VIP4 (/IMP) |
Oogenesis GO:0048477
The complete process of formation and maturation of an ovum or female gamete from a primordial female germ cell. Examples of this process are found in Mus musculus and Drosophila melanogaster.
|
2 | Q7JMZ1 (/TAS) Q9VIP4 (/TAS) |
Meiotic cell cycle GO:0051321
Progression through the phases of the meiotic cell cycle, in which canonically a cell replicates to produce four offspring with half the chromosomal content of the progenitor cell via two nuclear divisions.
|
2 | Q7JMZ1 (/IGI) Q9VIP4 (/IGI) |
Regulation of cell cycle GO:0051726
Any process that modulates the rate or extent of progression through the cell cycle.
|
2 | Q7JMZ1 (/IMP) Q9VIP4 (/IMP) |
Organelle transport along microtubule GO:0072384
The directed movement of an organelle along a microtubule, mediated by motor proteins. This process begins with the attachment of an organelle to a microtubule, and ends when the organelle reaches its final destination.
|
2 | B7ZC32 (/ISS) D3YXS5 (/ISS) |
Cytokinesis GO:0000910
The division of the cytoplasm and the plasma membrane of a cell and its partitioning into two daughter cells.
|
1 | Q9H1H9 (/IMP) |
Cytokinesis GO:0000910
The division of the cytoplasm and the plasma membrane of a cell and its partitioning into two daughter cells.
|
1 | Q9EQW7 (/ISS) |
Protein targeting GO:0006605
The process of targeting specific proteins to particular regions of the cell, typically membrane-bounded subcellular organelles. Usually requires an organelle specific protein sequence motif.
|
1 | Q9NQT8 (/TAS) |
Intracellular protein transport GO:0006886
The directed movement of proteins in a cell, including the movement of proteins between specific compartments or structures within a cell, such as organelles of a eukaryotic cell.
|
1 | Q9H1H9 (/IMP) |
Intracellular protein transport GO:0006886
The directed movement of proteins in a cell, including the movement of proteins between specific compartments or structures within a cell, such as organelles of a eukaryotic cell.
|
1 | Q9EQW7 (/ISO) |
Intracellular protein transport GO:0006886
The directed movement of proteins in a cell, including the movement of proteins between specific compartments or structures within a cell, such as organelles of a eukaryotic cell.
|
1 | Q9EQW7 (/ISS) |
Mitochondrion organization GO:0007005
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitochondrion; includes mitochondrial morphogenesis and distribution, and replication of the mitochondrial genome as well as synthesis of new mitochondrial components.
|
1 | F8WLE0 (/IDA) |
Microtubule-based movement GO:0007018
A microtubule-based process that results in the movement of organelles, other microtubules, or other cellular components. Examples include motor-driven movement along microtubules and movement driven by polymerization or depolymerization of microtubules.
|
1 | Q9NQT8 (/TAS) |
Signal transduction GO:0007165
The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.
|
1 | Q9NQT8 (/NAS) |
Endosome to lysosome transport GO:0008333
The directed movement of substances from endosomes to lysosomes.
|
1 | Q9H1H9 (/IMP) |
Endosome to lysosome transport GO:0008333
The directed movement of substances from endosomes to lysosomes.
|
1 | Q9EQW7 (/ISO) |
Endosome to lysosome transport GO:0008333
The directed movement of substances from endosomes to lysosomes.
|
1 | Q9EQW7 (/ISS) |
Melanosome organization GO:0032438
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a melanosome. A melanosome is a tissue-specific, membrane-bounded cytoplasmic organelle within which melanin pigments are synthesized and stored.
|
1 | Q9H1H9 (/IMP) |
Melanosome organization GO:0032438
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a melanosome. A melanosome is a tissue-specific, membrane-bounded cytoplasmic organelle within which melanin pigments are synthesized and stored.
|
1 | Q9EQW7 (/ISO) |
Melanosome organization GO:0032438
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a melanosome. A melanosome is a tissue-specific, membrane-bounded cytoplasmic organelle within which melanin pigments are synthesized and stored.
|
1 | Q9EQW7 (/ISS) |
Cargo loading into vesicle GO:0035459
The formation of a macromolecular complex between the coat proteins and proteins and/or lipoproteins that are going to be transported by a vesicle.
|
1 | Q9H1H9 (/IMP) |
Cargo loading into vesicle GO:0035459
The formation of a macromolecular complex between the coat proteins and proteins and/or lipoproteins that are going to be transported by a vesicle.
|
1 | Q9EQW7 (/ISO) |
Cargo loading into vesicle GO:0035459
The formation of a macromolecular complex between the coat proteins and proteins and/or lipoproteins that are going to be transported by a vesicle.
|
1 | Q9EQW7 (/ISS) |
T cell activation GO:0042110
The change in morphology and behavior of a mature or immature T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.
|
1 | Q9NQT8 (/NAS) |
Golgi to plasma membrane protein transport GO:0043001
The directed movement of proteins from the Golgi to the plasma membrane in transport vesicles that move from the trans-Golgi network to the plasma membrane.
|
1 | Q9EQW7 (/IDA) |
Golgi to plasma membrane protein transport GO:0043001
The directed movement of proteins from the Golgi to the plasma membrane in transport vesicles that move from the trans-Golgi network to the plasma membrane.
|
1 | Q9H1H9 (/ISS) |
Regulation of axonogenesis GO:0050770
Any process that modulates the frequency, rate or extent of axonogenesis, the generation of an axon, the long process of a neuron.
|
1 | Q9NQT8 (/IDA) |
Regulation of axonogenesis GO:0050770
Any process that modulates the frequency, rate or extent of axonogenesis, the generation of an axon, the long process of a neuron.
|
1 | E9Q4K7 (/ISO) |
Actin filament bundle assembly GO:0051017
The assembly of actin filament bundles; actin filaments are on the same axis but may be oriented with the same or opposite polarities and may be packed with different levels of tightness.
|
1 | R4JU55 (/IDA) |
Plus-end-directed vesicle transport along microtubule GO:0072383
The directed movement of a vesicle towards the plus end of a microtubule, mediated by motor proteins. This process begins with the attachment of a vesicle to a microtubule, and ends when the vesicle reaches its final destination.
|
1 | Q9EQW7 (/IDA) |
Plus-end-directed vesicle transport along microtubule GO:0072383
The directed movement of a vesicle towards the plus end of a microtubule, mediated by motor proteins. This process begins with the attachment of a vesicle to a microtubule, and ends when the vesicle reaches its final destination.
|
1 | Q9H1H9 (/ISS) |
Organelle transport along microtubule GO:0072384
The directed movement of an organelle along a microtubule, mediated by motor proteins. This process begins with the attachment of an organelle to a microtubule, and ends when the organelle reaches its final destination.
|
1 | F8WLE0 (/IMP) |
There are 33 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Kinesin complex GO:0005871
Any complex that includes a dimer of molecules from the kinesin superfamily, a group of related proteins that contain an extended region of predicted alpha-helical coiled coil in the main chain that likely produces dimerization. The native complexes of several kinesin family members have also been shown to contain additional peptides, often designated light chains as all of the noncatalytic subunits that are currently known are smaller than the chain that contains the motor unit. Kinesin complexes generally possess a force-generating enzymatic activity, or motor, which converts the free energy of the gamma phosphate bond of ATP into mechanical work.
|
7 | A0A0B4KFR5 (/ISS) A0A0B4KG24 (/ISS) A0A0B4LGK5 (/ISS) A1ZA18 (/ISS) A4UZI0 (/ISS) Q7JMZ1 (/ISS) Q9VIP4 (/ISS) |
Early endosome GO:0005769
A membrane-bounded organelle that receives incoming material from primary endocytic vesicles that have been generated by clathrin-dependent and clathrin-independent endocytosis; vesicles fuse with the early endosome to deliver cargo for sorting into recycling or degradation pathways.
|
5 | A0A0B4KFR5 (/IDA) A0A0B4KG24 (/IDA) A0A0B4LGK5 (/IDA) A1ZA18 (/IDA) A4UZI0 (/IDA) |
Axon GO:0030424
The long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminals and varicosities, which are sites of storage and release of neurotransmitter.
|
5 | G5EFQ4 (/IDA) Q20888 (/IDA) Q8IG10 (/IDA) Q8MQ20 (/IDA) Q9NQT8 (/IDA) |
Microtubule plus-end GO:0035371
The growing (plus) end of a microtubule. In vitro, microtubules polymerize more quickly at the plus end than at the minus end. In vivo, microtubule growth occurs only at the plus end, and the plus end switches between periods of growth and shortening, a behavior known as dynamic instability.
|
5 | A0A0B4KFR5 (/IDA) A0A0B4KG24 (/IDA) A0A0B4LGK5 (/IDA) A1ZA18 (/IDA) A4UZI0 (/IDA) |
Neuronal cell body GO:0043025
The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites.
|
4 | G5EFQ4 (/IDA) Q20888 (/IDA) Q8IG10 (/IDA) Q8MQ20 (/IDA) |
Cytoplasmic microtubule GO:0005881
Any microtubule in the cytoplasm of a cell.
|
3 | Q20888 (/IDA) Q8IG10 (/IDA) Q8MQ20 (/IDA) |
Mitochondrial membrane GO:0031966
Either of the lipid bilayers that surround the mitochondrion and form the mitochondrial envelope.
|
3 | B7ZC32 (/ISS) D3YXS5 (/ISS) G5EFQ4 (/ISS) |
Heterochromatin GO:0000792
A compact and highly condensed form of chromatin.
|
2 | Q7JMZ1 (/IDA) Q9VIP4 (/IDA) |
Intracellular GO:0005622
The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
|
2 | B7ZC32 (/ISS) D3YXS5 (/ISS) |
Intracellular GO:0005622
The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
|
1 | F8WLE0 (/IMP) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | Q9NQT8 (/IDA) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | E9Q4K7 (/ISO) |
Centrosome GO:0005813
A structure comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle.
|
1 | Q9H1H9 (/IDA) |
Centrosome GO:0005813
A structure comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle.
|
1 | Q9EQW7 (/ISO) |
Centrosome GO:0005813
A structure comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle.
|
1 | Q9EQW7 (/ISS) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | A0A0G2K8Z9 (/IDA) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | E9Q4K7 (/ISO) |
Microvillus GO:0005902
Thin cylindrical membrane-covered projections on the surface of an animal cell containing a core bundle of actin filaments. Present in especially large numbers on the absorptive surface of intestinal cells.
|
1 | A0A0G2K8Z9 (/IDA) |
Microvillus GO:0005902
Thin cylindrical membrane-covered projections on the surface of an animal cell containing a core bundle of actin filaments. Present in especially large numbers on the absorptive surface of intestinal cells.
|
1 | E9Q4K7 (/ISO) |
Endosome membrane GO:0010008
The lipid bilayer surrounding an endosome.
|
1 | Q9H1H9 (/IDA) |
Endosome membrane GO:0010008
The lipid bilayer surrounding an endosome.
|
1 | Q9EQW7 (/ISO) |
Endosome membrane GO:0010008
The lipid bilayer surrounding an endosome.
|
1 | Q9EQW7 (/ISS) |
Axon GO:0030424
The long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminals and varicosities, which are sites of storage and release of neurotransmitter.
|
1 | E9Q4K7 (/ISO) |
Dendrite GO:0030425
A neuron projection that has a short, tapering, often branched, morphology, receives and integrates signals from other neurons or from sensory stimuli, and conducts a nerve impulse towards the axon or the cell body. In most neurons, the impulse is conveyed from dendrites to axon via the cell body, but in some types of unipolar neuron, the impulse does not travel via the cell body.
|
1 | G5EFQ4 (/IDA) |
Midbody GO:0030496
A thin cytoplasmic bridge formed between daughter cells at the end of cytokinesis. The midbody forms where the contractile ring constricts, and may persist for some time before finally breaking to complete cytokinesis.
|
1 | Q9H1H9 (/IDA) |
Midbody GO:0030496
A thin cytoplasmic bridge formed between daughter cells at the end of cytokinesis. The midbody forms where the contractile ring constricts, and may persist for some time before finally breaking to complete cytokinesis.
|
1 | Q9EQW7 (/ISO) |
Midbody GO:0030496
A thin cytoplasmic bridge formed between daughter cells at the end of cytokinesis. The midbody forms where the contractile ring constricts, and may persist for some time before finally breaking to complete cytokinesis.
|
1 | Q9EQW7 (/ISS) |
Mitochondrial membrane GO:0031966
Either of the lipid bilayers that surround the mitochondrion and form the mitochondrial envelope.
|
1 | F8WLE0 (/IDA) |
Trans-Golgi network membrane GO:0032588
The lipid bilayer surrounding any of the compartments that make up the trans-Golgi network.
|
1 | Q9EQW7 (/IDA) |
Trans-Golgi network membrane GO:0032588
The lipid bilayer surrounding any of the compartments that make up the trans-Golgi network.
|
1 | Q9H1H9 (/ISS) |
Paranode region of axon GO:0033270
An axon part that is located adjacent to the nodes of Ranvier and surrounded by lateral loop portions of myelin sheath.
|
1 | A0A0G2K8Z9 (/IDA) |
Paranode region of axon GO:0033270
An axon part that is located adjacent to the nodes of Ranvier and surrounded by lateral loop portions of myelin sheath.
|
1 | E9Q4K7 (/ISO) |
Non-motile cilium GO:0097730
A cilium which may have a variable array of axonemal microtubules but does not contain molecular motors.
|
1 | G5EFQ4 (/IDA) |