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CATH Superfamily 2.60.120.330

B-lactam Antibiotic, Isopenicillin N Synthase; Chain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
B-lactam Antibiotic, Isopenicillin N Synthase; Chain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 5294: Gibberellin 3-beta-dioxygenase (Ethylene-forming e...

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
2-oxuglutarate dioxygenase (ethylene-forming). [EC: 1.13.12.19]
2-oxoglutarate + O(2) = ethylene + 3 CO(2) + H(2)O.
  • This is one of two simultaneous reactions catalyzed by the enzyme, which is responsible for ethylene production in bacteria of the Pseudomonas syringae group.
  • In the other reaction (EC 1.14.11.34) the enzyme catalyzes the mono- oxygenation of both 2-oxoglutarate and L-arginine, forming succinate, carbon dioxide and L-hydroxyarginine, which is subsequently cleaved into guanidine and (S)-1-pyrroline-5-carboxylate.
  • The enzymes catalyze two cycles of the ethylene-forming reaction for each cycle of the succinate-forming reaction, so that the stoichiometry of the products ethylene and succinate is 2:1.
 17 A0A0K1ZTH9 A0A0S4TXD7 A0A0S4U8W0 A0A0S4W6S6 A0A0S4WBE2 A0A0S4WRH4 A0A100JJ83 A1Z3B9 E7PUE2 F3GA12
(7 more...)
2-oxoglutarate/L-arginine monooxygenase/decarboxylase (succinate- forming). [EC: 1.14.11.34]
2-oxoglutarate + L-arginine + O(2) = succinate + CO(2) + guanidine + (S)- 1-pyrroline-5-carboxylate + H(2)O.
  • This is one of two simultaneous reactions catalyzed by the enzyme, which is responsible for ethylene production in bacteria of the Pseudomonas syringae group.
  • In the other reaction (EC 1.13.12.19) the enzyme catalyzes the dioxygenation of 2-oxoglutarate forming ethylene and three molecules of carbon dioxide.
  • The enzyme catalyzes two cycles of the ethylene-forming reaction for each cycle of the succinate-forming reaction, so that the stoichiometry of the products ethylene and succinate is 2:1.
 16 A0A0K1ZTH9 A0A0S4TXD7 A0A0S4U8W0 A0A0S4W6S6 A0A0S4WBE2 A0A0S4WRH4 A1Z3B9 E7PUE2 F3GA12 P32021
(6 more...)
Gibberellin 3-beta-dioxygenase. [EC: 1.14.11.15]
Gibberellin 20 + 2-oxoglutarate + O(2) = gibberellin 1 + succinate + CO(2).
    		 4 A0A177RKF2 D8N2S3 D8NF45 D8P6F8
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