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CATH Superfamily 2.60.120.200

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 25124: Terribly reduced optic lobes, isoform AY

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 1 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Dystroglycan binding GO:0002162
Interacting selectively and non-covalently with dystroglycan. Dystroglycan is glycoprotein found in non-muscle tissues as well as in muscle tissues, often in association with dystrophin. The native dystroglycan cleaved into two non-covalently associated subunits, alpha (N-terminal) and beta (C-terminal).
 1 G5EG68 (/IPI)

There are 10 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Defasciculation of motor neuron axon GO:0007415
Separation of a motor axon away from a bundle of axons known as a fascicle.
 21 A0A023GRW4 (/IMP) E1JJC0 (/IMP) M9NDL5 (/IMP) M9NDM1 (/IMP) M9NE56 (/IMP) M9NE61 (/IMP) M9NES6 (/IMP) M9NET2 (/IMP) M9NFR6 (/IMP) M9NFS1 (/IMP)
(11 more)
Motor neuron axon guidance GO:0008045
The process in which the migration of an axon growth cone of a motor neuron is directed to a specific target site in response to a combination of attractive and repulsive cues.
 21 A0A023GRW4 (/IMP) E1JJC0 (/IMP) M9NDL5 (/IMP) M9NDM1 (/IMP) M9NE56 (/IMP) M9NE61 (/IMP) M9NES6 (/IMP) M9NET2 (/IMP) M9NFR6 (/IMP) M9NFS1 (/IMP)
(11 more)
Maintenance of epithelial cell apical/basal polarity GO:0045199
The maintenance of the apicobasal polarity of an epithelial cell.
 21 A0A023GRW4 (/IMP) E1JJC0 (/IMP) M9NDL5 (/IMP) M9NDM1 (/IMP) M9NE56 (/IMP) M9NE61 (/IMP) M9NES6 (/IMP) M9NET2 (/IMP) M9NFR6 (/IMP) M9NFS1 (/IMP)
(11 more)
Response to anesthetic GO:0072347
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an anesthetic stimulus. An anesthetic is a substance that causes loss of feeling, awareness, or sensation.
 21 A0A023GRW4 (/IMP) E1JJC0 (/IMP) M9NDL5 (/IMP) M9NDM1 (/IMP) M9NE56 (/IMP) M9NE61 (/IMP) M9NES6 (/IMP) M9NET2 (/IMP) M9NFR6 (/IMP) M9NFS1 (/IMP)
(11 more)
Positive regulation of semaphorin-plexin signaling pathway GO:2001262
Any process that activates or increases the frequency, rate or extent of semaphorin-plexin signaling pathway.
 21 A0A023GRW4 (/IGI) E1JJC0 (/IGI) M9NDL5 (/IGI) M9NDM1 (/IGI) M9NE56 (/IGI) M9NE61 (/IGI) M9NES6 (/IGI) M9NET2 (/IGI) M9NFR6 (/IGI) M9NFS1 (/IGI)
(11 more)
Establishment or maintenance of cell polarity GO:0007163
Any cellular process that results in the specification, formation or maintenance of anisotropic intracellular organization or cell growth patterns.
 1 Q19319 (/IMP)
Axon guidance GO:0007411
The chemotaxis process that directs the migration of an axon growth cone to a specific target site in response to a combination of attractive and repulsive cues.
 1 Q19319 (/IMP)
Skeletal muscle tissue regeneration GO:0043403
The regrowth of skeletal muscle tissue to repair injured or damaged muscle fibers in the postnatal stage.
 1 Q5T1H1 (/IMP)
Detection of light stimulus involved in visual perception GO:0050908
The series of events involved in visual perception in which a light stimulus is received and converted into a molecular signal.
 1 Q5T1H1 (/IMP)
Neuroblast migration GO:0097402
The orderly movement of a neuroblast from one site to another, often during the development of a multicellular organism or multicellular structure. A neuroblast is any cell that will divide and give rise to a neuron.
 1 Q19319 (/IMP)

There are 6 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Basement membrane GO:0005604
A thin layer of dense material found in various animal tissues interposed between the cells and the adjacent connective tissue. It consists of the basal lamina plus an associated layer of reticulin fibers.
 4 M9NET2 (/ISS) M9NFS1 (/ISS) M9NGK3 (/ISS) Q8MPN3 (/ISS)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
 4 M9NET2 (/IDA) M9NFS1 (/IDA) M9NGK3 (/IDA) Q8MPN3 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
 4 M9NET2 (/IDA) M9NFS1 (/IDA) M9NGK3 (/IDA) Q8MPN3 (/IDA)
Basement membrane GO:0005604
A thin layer of dense material found in various animal tissues interposed between the cells and the adjacent connective tissue. It consists of the basal lamina plus an associated layer of reticulin fibers.
 1 Q9W4Y3 (/IDA)
Basal lamina GO:0005605
A thin sheet of proteoglycans and glycoproteins, especially laminin, secreted by cells as an extracellular matrix.
 1 G5EG68 (/IDA)
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
 1 Q5T1H1 (/IDA)