The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Jelly Rolls
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 54838: Neuropathy target esterase sws

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Lysophospholipase activity GO:0004622
Catalysis of the reaction: 2-lysophosphatidylcholine + H2O = glycerophosphocholine + a carboxylate.
10 B3MRI9 (/ISS) B3NY03 (/ISS) B4H3U8 (/ISS) B4IL64 (/ISS) B4JLX2 (/ISS) B4L535 (/ISS) B4M709 (/ISS) B4N1W9 (/ISS) B4Q0P3 (/ISS) B5DKS8 (/ISS)
Lysophospholipase activity GO:0004622
Catalysis of the reaction: 2-lysophosphatidylcholine + H2O = glycerophosphocholine + a carboxylate.
1 Q9U969 (/IDA)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
1 Q9U969 (/IPI)
Protein kinase A catalytic subunit binding GO:0034236
Interacting selectively and non-covalently with one or both of the catalytic subunits of protein kinase A.
1 Q9U969 (/IPI)

There are 16 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Membrane lipid metabolic process GO:0006643
The chemical reactions and pathways involving membrane lipids, any lipid found in or associated with a biological membrane.
10 B3MRI9 (/ISS) B3NY03 (/ISS) B4H3U8 (/ISS) B4IL64 (/ISS) B4JLX2 (/ISS) B4L535 (/ISS) B4M709 (/ISS) B4N1W9 (/ISS) B4Q0P3 (/ISS) B5DKS8 (/ISS)
Glial cell apoptotic process GO:0034349
Any apoptotic process in a glial cell, a non-neuronal cell of the nervous system.
10 B3MRI9 (/ISS) B3NY03 (/ISS) B4H3U8 (/ISS) B4IL64 (/ISS) B4JLX2 (/ISS) B4L535 (/ISS) B4M709 (/ISS) B4N1W9 (/ISS) B4Q0P3 (/ISS) B5DKS8 (/ISS)
Phosphatidylcholine metabolic process GO:0046470
The chemical reactions and pathways involving phosphatidylcholines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline. They are important constituents of cell membranes.
10 B3MRI9 (/ISS) B3NY03 (/ISS) B4H3U8 (/ISS) B4IL64 (/ISS) B4JLX2 (/ISS) B4L535 (/ISS) B4M709 (/ISS) B4N1W9 (/ISS) B4Q0P3 (/ISS) B5DKS8 (/ISS)
Neuron apoptotic process GO:0051402
Any apoptotic process in a neuron, the basic cellular unit of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the nervous system.
10 B3MRI9 (/ISS) B3NY03 (/ISS) B4H3U8 (/ISS) B4IL64 (/ISS) B4JLX2 (/ISS) B4L535 (/ISS) B4M709 (/ISS) B4N1W9 (/ISS) B4Q0P3 (/ISS) B5DKS8 (/ISS)
Membrane organization GO:0061024
A process which results in the assembly, arrangement of constituent parts, or disassembly of a membrane. A membrane is a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.
10 B3MRI9 (/ISS) B3NY03 (/ISS) B4H3U8 (/ISS) B4IL64 (/ISS) B4JLX2 (/ISS) B4L535 (/ISS) B4M709 (/ISS) B4N1W9 (/ISS) B4Q0P3 (/ISS) B5DKS8 (/ISS)
Membrane lipid metabolic process GO:0006643
The chemical reactions and pathways involving membrane lipids, any lipid found in or associated with a biological membrane.
1 Q9U969 (/IDA)
Phospholipid metabolic process GO:0006644
The chemical reactions and pathways involving phospholipids, any lipid containing phosphoric acid as a mono- or diester.
1 Q9U969 (/IMP)
Ensheathment of neurons GO:0007272
The process in which glial cells envelop neuronal cell bodies and/or axons to form an insulating layer. This can take the form of myelinating or non-myelinating ensheathment.
1 Q9U969 (/IMP)
Sensory perception of smell GO:0007608
The series of events required for an organism to receive an olfactory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Olfaction involves the detection of chemical composition of an organism's ambient medium by chemoreceptors. This is a neurological process.
1 Q9U969 (/IMP)
Glial cell apoptotic process GO:0034349
Any apoptotic process in a glial cell, a non-neuronal cell of the nervous system.
1 Q9U969 (/IMP)
Photoreceptor cell maintenance GO:0045494
Any process preventing the degeneration of the photoreceptor, a specialized cell type that is sensitive to light.
1 Q9U969 (/IMP)
Phosphatidylcholine metabolic process GO:0046470
The chemical reactions and pathways involving phosphatidylcholines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline. They are important constituents of cell membranes.
1 Q9U969 (/IDA)
Neuron apoptotic process GO:0051402
Any apoptotic process in a neuron, the basic cellular unit of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the nervous system.
1 Q9U969 (/IMP)
Membrane organization GO:0061024
A process which results in the assembly, arrangement of constituent parts, or disassembly of a membrane. A membrane is a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.
1 Q9U969 (/IDA)
Protein localization to membrane GO:0072657
A process in which a protein is transported to, or maintained in, a specific location in a membrane.
1 Q9U969 (/IMP)
Negative regulation of cAMP-dependent protein kinase activity GO:2000480
Any process that stops, prevents or reduces the frequency, rate or extent of cAMP-dependent protein kinase activity.
1 Q9U969 (/IMP)

There are 4 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Endoplasmic reticulum membrane GO:0005789
The lipid bilayer surrounding the endoplasmic reticulum.
10 B3MRI9 (/ISS) B3NY03 (/ISS) B4H3U8 (/ISS) B4IL64 (/ISS) B4JLX2 (/ISS) B4L535 (/ISS) B4M709 (/ISS) B4N1W9 (/ISS) B4Q0P3 (/ISS) B5DKS8 (/ISS)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q9U969 (/IDA)
Endoplasmic reticulum membrane GO:0005789
The lipid bilayer surrounding the endoplasmic reticulum.
1 Q9U969 (/IDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 Q9U969 (/IDA)