The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:
"Jelly Rolls
".
FunFam 54523: DNA-binding transcriptional dual regulator Crp
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 13 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Transcription regulatory region sequence-specific DNA binding GO:0000976
Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon.
|
8 | A0KST7 (/IDA) O34015 (/IDA) P55222 (/IDA) Q5E2H1 (/IDA) Q7CFV3 (/IDA) Q7M7I9 (/IDA) Q88QR4 (/IDA) Q9KNW6 (/IDA) |
|
Bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding GO:0001216
Interacting selectively and non-covalently with a specific DNA sequence in order to activate or increase the frequency, rate or extent of transcription by bacterial-type RNA polymerase. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.
|
6 | A0KST7 (/IDA) P55222 (/IDA) Q5E2H1 (/IDA) Q7M7I9 (/IDA) Q88QR4 (/IDA) Q9KNW6 (/IDA) |
|
Transcription regulatory region sequence-specific DNA binding GO:0000976
Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon.
|
5 | O34015 (/IPI) P55222 (/IPI) Q7CFV3 (/IPI) Q7M7I9 (/IPI) Q88QR4 (/IPI) |
|
Transcription regulatory region sequence-specific DNA binding GO:0000976
Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon.
|
4 | P0A2T6 (/EXP) P55222 (/EXP) Q7M7I9 (/EXP) Q88QR4 (/EXP) |
|
Bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding GO:0001216
Interacting selectively and non-covalently with a specific DNA sequence in order to activate or increase the frequency, rate or extent of transcription by bacterial-type RNA polymerase. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.
|
4 | P0A2T6 (/EXP) P55222 (/EXP) Q7M7I9 (/EXP) Q88QR4 (/EXP) |
|
Bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding GO:0001216
Interacting selectively and non-covalently with a specific DNA sequence in order to activate or increase the frequency, rate or extent of transcription by bacterial-type RNA polymerase. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.
|
4 | P55222 (/IPI) Q7CFV3 (/IPI) Q7M7I9 (/IPI) Q88QR4 (/IPI) |
|
Bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding GO:0001217
Interacting selectively and non-covalently with a specific DNA sequence in order to stop, prevent, or reduce the frequency, rate or extent of transcription by bacterial-type RNA polymerase. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.
|
4 | O34015 (/IDA) P55222 (/IDA) Q7CFV3 (/IDA) Q7M7I9 (/IDA) |
|
Bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding GO:0001217
Interacting selectively and non-covalently with a specific DNA sequence in order to stop, prevent, or reduce the frequency, rate or extent of transcription by bacterial-type RNA polymerase. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.
|
3 | O34015 (/IPI) P55222 (/IPI) Q7CFV3 (/IPI) |
|
Bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding GO:0001217
Interacting selectively and non-covalently with a specific DNA sequence in order to stop, prevent, or reduce the frequency, rate or extent of transcription by bacterial-type RNA polymerase. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.
|
2 | P55222 (/EXP) Q7M7I9 (/EXP) |
|
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
|
2 | P0ACJ8 (/IPI) P55222 (/IPI) |
|
Transcription factor activity, sequence-specific DNA binding GO:0003700
Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.
|
1 | Q9KNW6 (/ISS) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | P0ACJ8 (/IPI) |
|
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
|
1 | P0ACJ8 (/IDA) |
There are 14 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
|
6 | A0KST7 (/EXP) P0ACJ8 (/EXP) Q5E2H1 (/EXP) Q7CFV3 (/EXP) Q7M7I9 (/EXP) Q9KNW6 (/EXP) |
|
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
|
3 | P0ACJ8 (/EXP) Q7CFV3 (/EXP) Q7M7I9 (/EXP) |
|
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
|
3 | P0ACJ8 (/IDA) P55222 (/IDA) Q7M7I9 (/IDA) |
|
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
|
3 | P0A2T6 (/IEP) Q7CFV3 (/IEP) Q7M7I9 (/IEP) |
|
Transcription, DNA-templated GO:0006351
The cellular synthesis of RNA on a template of DNA.
|
2 | P0ACJ8 (/IMP) P55222 (/IMP) |
|
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
|
2 | P0ACJ8 (/IDA) Q7M7I9 (/IDA) |
|
Transcription, DNA-templated GO:0006351
The cellular synthesis of RNA on a template of DNA.
|
1 | P0ACJ8 (/IDA) |
|
Transcription, DNA-templated GO:0006351
The cellular synthesis of RNA on a template of DNA.
|
1 | P0ACJ8 (/IEP) |
|
Transcription, DNA-templated GO:0006351
The cellular synthesis of RNA on a template of DNA.
|
1 | P0ACJ8 (/ISS) |
|
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
|
1 | Q9KNW6 (/ISS) |
|
Pathogenesis GO:0009405
The set of specific processes that generate the ability of an organism to induce an abnormal, generally detrimental state in another organism.
|
1 | P55222 (/IMP) |
|
Positive regulation of multi-organism process GO:0043902
Any process that activates or increases the frequency, rate or extent of a multi-organism process, a process in which an organism has an effect on another organism of the same or different species.
|
1 | P55222 (/IMP) |
|
Carbon catabolite repression of transcription GO:0045013
A transcription regulation process in which the presence of one carbon source leads to a decrease in the frequency, rate, or extent of transcription of specific genes involved in the metabolism of other carbon sources. Carbon catabolite repression is a mechanism of genetic regulation which the accumulation of catabolites of one substance in the cell represses the formation of enzymes that contribute to the catabolism of other substances.
|
1 | P0ACJ8 (/IMP) |
|
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
|
1 | Q7CFV3 (/IEP) |
There are 4 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein-DNA complex GO:0032993
A macromolecular complex containing both protein and DNA molecules.
|
9 | A0KST7 (/IDA) O34015 (/IDA) P0ACJ8 (/IDA) P55222 (/IDA) Q5E2H1 (/IDA) Q7CFV3 (/IDA) Q7M7I9 (/IDA) Q88QR4 (/IDA) Q9KNW6 (/IDA) |
|
Protein-DNA complex GO:0032993
A macromolecular complex containing both protein and DNA molecules.
|
6 | O34015 (/IPI) P0ACJ8 (/IPI) P55222 (/IPI) Q7CFV3 (/IPI) Q7M7I9 (/IPI) Q88QR4 (/IPI) |
|
Protein-DNA complex GO:0032993
A macromolecular complex containing both protein and DNA molecules.
|
4 | P0A2T6 (/EXP) P55222 (/EXP) Q7M7I9 (/EXP) Q88QR4 (/EXP) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | P0ACJ8 (/IDA) |