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CATH Superfamily 2.40.50.140

Nucleic acid-binding proteins

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Nucleic acid-binding proteins
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 56220: 23S rRNA (uracil(1939)-C(5))-methyltransferase Rlm...

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
23S rRNA (uracil(1939)-C(5))-methyltransferase. [EC: 2.1.1.190]
S-adenosyl-L-methionine + uracil(1939) in 23S rRNA = S-adenosyl-L- homocysteine + 5-methyluracil(1939) in 23S rRNA.
  • The enzyme specifically methylates uracil(1939) at C(5) in 23S rRNA.
  • The enzyme contains an [4Fe-4S] cluster coordinated by four conserved cysteine residues.
 10 A0A128VEW4 A0A129JYI5 A0A130K8T7 A0A131M0Z5 A0A1K2GJR1 A5IBU7 G8UWL8 Q5WW81 Q5X5A8 Q5ZVI4