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CATH Superfamily 2.40.50.140

Nucleic acid-binding proteins

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Nucleic acid-binding proteins
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 54800: 30S ribosomal protein S1

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
4-hydroxy-3-methylbut-2-enyl diphosphate reductase. [EC: 1.17.7.4]
(1) Isopentenyl diphosphate + 2 oxidized ferredoxin [iron-sulfur] cluster + H(2)O = (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate + 2 reduced ferredoxin [iron-sulfur] cluster + 2 H(+). (2) Dimethylallyl diphosphate + 2 oxidized ferredoxin [iron-sulfur] cluster + H(2)O = (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate + 2 reduced ferredoxin [iron-sulfur] cluster + 2 H(+).
  • Forms a system with a ferredoxin or a flavodoxin and an NAD(P)H-dependent reductase.
  • This is the last enzyme in the non-mevalonate pathway for isoprenoid biosynthesis.
  • This pathway, also known as the 1-deoxy-D-xylulose 5-phosphate (DOXP) or as the 2-C-methyl-D-erythritol-4-phosphate (MEP) pathway, is found in most bacteria and in plant chloroplasts.
  • The enzyme acts in the reverse direction, producing a 5:1 mixture of isopentenyl diphosphate and dimethylallyl diphosphate.
  • Formerly EC 1.17.1.2.
 38 A0A095WFW9 A0A0M1VVY7 A0A0M4RDM4 A0A0S2ZHF3 A0A0S2ZLL3 A0A0S2ZWI6 A0A101K6Y7 A0A133PEH3 A0A140PQZ7 A0A162M8K1
(28 more...)
Transferred entry: 1.17.7.4. [EC: 1.17.1.2]
    		2 B9KD73 Q1CSL2
    Polyribonucleotide nucleotidyltransferase. [EC: 2.7.7.8]
    RNA(n+1) + phosphate = RNA(n) + a nucleoside diphosphate.
    • ADP, IDP, GDP, UDP and CDP can act as donors.
    		 1 B5Y8I4