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CATH Superfamily 2.40.50.140

Nucleic acid-binding proteins

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Nucleic acid-binding proteins
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 54761: ATP-dependent RNA helicase DHX8

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
RNA helicase. [EC: 3.6.4.13]
ATP + H(2)O = ADP + phosphate.
  • RNA helicases utilize the energy from ATP hydrolysis to unwind RNA.
  • Some of them unwind RNA with a 3' to 5' polarity, other show 5' to 3' polarity.
  • Some helicases unwind DNA as well as RNA.
  • May be identical with EC 3.6.4.12 (DNA helicase).
 24 A0A0L8VRV6 A0A0L8VRV6 A2A4P0 A2A4P0 B5VHE4 B5VHE4 C7GKJ1 C7GKJ1 H2QD51 H2QD51
(14 more...)
Polyribonucleotide nucleotidyltransferase. [EC: 2.7.7.8]
RNA(n+1) + phosphate = RNA(n) + a nucleoside diphosphate.
  • ADP, IDP, GDP, UDP and CDP can act as donors.
 24 A0A0B2C097 A0A0B2C097 A0A0B4E2A4 A0A0B4E2A4 A0A0C1GW48 A0A0C1GW48 A0A0C1IMI9 A0A0C1IMI9 A0A0C1ISG5 A0A0C1ISG5
(14 more...)
Adenosinetriphosphatase. [EC: 3.6.1.3]
ATP + H(2)O = ADP + phosphate.
  • Many enzymes previously listed under this number are now listed separately as EC 3.6.1.32 to EC 3.6.1.39.
  • The remaining enzymes, not separately listed on the basis of some function coupled with hydrolyzes of ATP, include enzymes dependent on Ca(2+), Mg(2+), anions, H(+) or DNA.
  • Formerly EC 3.6.1.4.
 12 A1Z9L3 A1Z9L3 B3MD00 B3MD00 B3NRD1 B3NRD1 B4LNR3 B4LNR3 B4P6M1 B4P6M1
(2 more...)