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CATH Superfamily 2.40.50.140

Nucleic acid-binding proteins

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Nucleic acid-binding proteins
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 53616: 23S rRNA m(5)U1939 methyltransferase

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
23S rRNA (uracil(1939)-C(5))-methyltransferase. [EC: 2.1.1.190]
S-adenosyl-L-methionine + uracil(1939) in 23S rRNA = S-adenosyl-L- homocysteine + 5-methyluracil(1939) in 23S rRNA.
  • The enzyme specifically methylates uracil(1939) at C(5) in 23S rRNA.
  • The enzyme contains an [4Fe-4S] cluster coordinated by four conserved cysteine residues.
 147 A0A059UQP2 A0A084CB05 A0A099E9E8 A0A099MWP5 A0A099SHG9 A0A0A7JI30 A0A0A7PXK7 A0A0B5K4A6 A0A0C1K9D6 A0A0C5RZK3
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