The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Nucleic acid-binding proteins
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 53260: Phenylalanine--tRNA ligase beta subunit

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Phenylalanine--tRNA ligase. [EC: 6.1.1.20]
ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + L-phenylalanyl- tRNA(Phe).
    221 A0A011NQK9 A0A011NZD4 A0A011P405 A0A011PMJ1 A0A014QAB5 A0A022GM37 A0A060NHR7 A0A076PT20 A0A080LTM0 A0A080MBA0
    (211 more...)
    23S rRNA (uracil(1939)-C(5))-methyltransferase. [EC: 2.1.1.190]
    S-adenosyl-L-methionine + uracil(1939) in 23S rRNA = S-adenosyl-L- homocysteine + 5-methyluracil(1939) in 23S rRNA.
    • The enzyme specifically methylates uracil(1939) at C(5) in 23S rRNA.
    • The enzyme contains an [4Fe-4S] cluster coordinated by four conserved cysteine residues.
    1 Q0A8Y4