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CATH Superfamily 2.40.50.140

Nucleic acid-binding proteins

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Nucleic acid-binding proteins
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 42387: 23S rRNA (Uracil-C(5))-methyltransferase RlmCD

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
23S rRNA (uracil(747)-C(5))-methyltransferase. [EC: 2.1.1.189]
S-adenosyl-L-methionine + uracil(747) in 23S rRNA = S-adenosyl-L- homocysteine + 5-methyluracil(747) in 23S rRNA.
  • The enzyme specifically methylates uracil(747) at C(5) in 23S rRNA.
 14 A0A0K6KAN7 A0A0K6KNE4 A0A0K6KNP8 A0A0K6LCY7 A0A0K6LLK0 A0A0K6M5E3 A0A0T8Q1N2 A0A0U0D7T5 A0A162QZE9 A0A1B2B2W5
(4 more...)
23S rRNA (uracil(1939)-C(5))-methyltransferase. [EC: 2.1.1.190]
S-adenosyl-L-methionine + uracil(1939) in 23S rRNA = S-adenosyl-L- homocysteine + 5-methyluracil(1939) in 23S rRNA.
  • The enzyme specifically methylates uracil(1939) at C(5) in 23S rRNA.
  • The enzyme contains an [4Fe-4S] cluster coordinated by four conserved cysteine residues.
 10 A0A0A0TNQ5 A0A162QZE9 A0A1A0CYM8 A0A1A5VAF8 A0A1B2B2W5 E1UN15 G4EZ79 L8AC79 O31503 S6FCW8