The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:
"Nucleic acid-binding proteins
".
FunFam 3622: Eukaryotic translation initiation factor 1A
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 6 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
2 | O14602 (/IPI) P47813 (/IPI) |
|
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
|
1 | P47813 (/IDA) |
|
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
|
1 | Q60872 (/ISO) |
|
Translation initiation factor activity GO:0003743
Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.
|
1 | Q9VEA1 (/ISS) |
|
Translation factor activity, RNA binding GO:0008135
Functions during translation by interacting selectively and non-covalently with RNA during polypeptide synthesis at the ribosome.
|
1 | P47813 (/TAS) |
|
Ribosomal large subunit binding GO:0043023
Interacting selectively and non-covalently with any part of the larger ribosomal subunit.
|
1 | Q6VV72 (/IDA) |
There are 5 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Translation GO:0006412
The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA. Translation ends with the release of a polypeptide chain from the ribosome.
|
1 | Q9VEA1 (/ISS) |
|
Translational initiation GO:0006413
The process preceding formation of the peptide bond between the first two amino acids of a protein. This includes the formation of a complex of the ribosome, mRNA, and an initiation complex that contains the first aminoacyl-tRNA.
|
1 | Q9VEA1 (/ISS) |
|
Translational initiation GO:0006413
The process preceding formation of the peptide bond between the first two amino acids of a protein. This includes the formation of a complex of the ribosome, mRNA, and an initiation complex that contains the first aminoacyl-tRNA.
|
1 | P47813 (/TAS) |
|
Phagocytosis GO:0006909
An endocytosis process that results in the engulfment of external particulate material by phagocytes. The particles are initially contained within phagocytic vacuoles (phagosomes), which then fuse with primary lysosomes to effect digestion of the particles.
|
1 | Q9VEA1 (/IMP) |
|
Smoothened signaling pathway GO:0007224
A series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened.
|
1 | Q9VEA1 (/IGI) |
There are 5 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
1 | Q9VEA1 (/IDA) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | Q9VEA1 (/IDA) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | Q9VEA1 (/ISS) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | P47813 (/TAS) |
|
Eukaryotic 43S preinitiation complex GO:0016282
A protein complex composed of the 40S ribosomal subunit plus eIF1A, eIF3, and eIF2-GTP-bound methionyl-initiator methionine tRNA.
|
1 | Q9VEA1 (/ISS) |