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CATH Superfamily 2.40.30.10

Translation factors

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Translation factors
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Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 38278: Predicted NADPH oxidase 5

There are 4 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
NAD(P)H oxidase (H(2)O(2)-forming). [EC: 1.6.3.1]
NAD(P)H + O(2) = NAD(P)(+) + H(2)O(2).
  • When calcium is present, this transmembrane glycoprotein generates H(2)O(2) by transfering electrons from intracellular NAD(P)H to extracellular molecular oxygen.
  • The electron bridge within the enzyme contains one molecule of FAD and probably two heme groups.
  • This flavoprotein is expressed at the apical membrane of thyrocytes, and provides H(2)O(2) for the thyroid peroxidase-catalyzed biosynthesis of thyroid hormones.
 56 A0A0B2NS90 A0A0B2P8S1 A0A0B2PQ25 A0A0B2Q6B2 A0A0B2Q872 A0A0B2QEA4 A0A0B2QVL6 A0A0B2RCY0 A0A0B2RPN2 A0A0B2S7Q0
(46 more...)
Ferric-chelate reductase (NADH). [EC: 1.16.1.7]
2 Fe(II)-siderophore + NAD(+) + H(+) = 2 Fe(III)-siderophore + NADH.
  • The enzyme catalyzes the reduction of bound ferric iron in a variety of iron chelators (siderophores), resulting in the release of ferrous iron.
  • The plant enzyme is involved in the transport of iron across plant plasma membranes.
  • The enzyme from the bacterium Paracoccus denitrificans can also reduce chromate.
  • Cf. EC 1.16.1.9 and EC 1.16.1.10.
  • Formerly EC 1.6.99.13.
 22 A0A167VG16 A0A178U9I2 A0A178UB87 A0A178UGW8 A0A178W4T7 A0A178WMG4 A2R084 B6HV51 B9WJM6 F4I4K7
(12 more...)
Peroxidase. [EC: 1.11.1.7]
2 phenolic donor + H(2)O(2) = 2 phenoxyl radical of the donor + 2 H(2)O.
    		 12 A0A0J9QUP3 A0A0J9TE69 A0A0Q5W8X9 A0A0Q9WI39 B3MLA0 B3NA67 B4LUX5 B4N013 B4NX88 M9PCF1
    (2 more...)
    Ribose-phosphate diphosphokinase. [EC: 2.7.6.1]
    ATP + D-ribose 5-phosphate = AMP + 5-phospho-alpha-D-ribose 1-diphosphate.
    • dATP can also act as donor.
    		 1 A0A075AR06
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