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CATH Superfamily 2.40.160.20

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 9714: Lipid A palmitoyltransferase PagP

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Lipid IV(A) palmitoyltransferase. [EC: 2.3.1.251]
(1) 1-palmitoyl-2-acyl-sn-glycero-3-phosphocholine + hexa-acyl lipid A = 2-acyl-sn-glycero-3-phosphocholine + hepta-acyl lipid A. (2) 1-palmitoyl-2-acyl-sn-glycero-3-phosphocholine + lipid II(A) = 2-acyl-sn-glycero-3-phosphocholine + lipid II(B). (3) 1-palmitoyl-2-acyl-sn-glycero-3-phosphocholine + lipid IV(A) = 2-acyl-sn-glycero-3-phosphocholine + lipid IV(B).
  • Isolated from the bacteria Escherichia coli and Salmonella typhimurium.
  • The enzyme prefers phosphatidylcholine with a palmitoyl group at the sn-1 position and palmitoyl or stearoyl groups at the sn-2 position.
  • There is some activity with corresponding phosphatidylserines but only weak activity with other diacylphosphatidyl compounds.
  • The enzyme also acts on Kdo-(2->4)-Kdo-(2->6)-lipid IV(A).
 998 A0A014N2G2 A0A022PE81 A0A023VAN4 A0A023YT52 A0A024KRJ1 A0A024L4N6 A0A025CFS7 A0A026RTS1 A0A026V598 A0A027TF71
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