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CATH Superfamily 2.40.110.10

Butyryl-CoA Dehydrogenase, subunit A, domain 2

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Butyryl-CoA Dehydrogenase, subunit A, domain 2
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 14326: Putative medium-chain acyl-coa dehydrogenase

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
2-methylacyl-CoA dehydrogenase. [EC: 1.3.99.12]
2-methylbutanoyl-CoA + acceptor = 2-methylbut-2-enoyl-CoA + reduced acceptor.
  • Also oxidizes 2-methylpropanoyl-CoA.
  • Not identical with EC 1.3.8.1, EC 1.3.8.7, EC 1.3.8.8 or EC 1.3.8.9.
 3 A0A0P7W745 A0A1E1UYB2 X5MHS0
Acryloyl-CoA reductase (NADH). [EC: 1.3.1.95]
Propanoyl-CoA + NAD(+) = acryloyl-CoA + NADH.
  • The reaction is catalyzed in the opposite direction to that shown.
  • The enzyme from the bacterium Clostridium propionicum is a complex that includes an electron-transfer flavoprotein (ETF).
  • The ETF is reduced by NADH and transfers the electrons to the active site.
  • Catalyzes a step in a pathway for L-alanine fermentation to propanoate.
  • Cf. EC 1.3.1.84.
 1 A0A161VBL2
Transferred entry: 1.3.8.1. [EC: 1.3.99.2]
    		1 B7PJR8
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