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CATH Superfamily 2.40.10.240

QueA-like

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
QueA-like
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 405: S-adenosylmethionine:tRNA ribosyltransferase-isome...

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
S-adenosylmethionine:tRNA ribosyltransferase-isomerase. [EC: 2.4.99.17]
S-adenosyl-L-methionine + 7-aminomethyl-7-carbaguanosine(34) in tRNA = L-methionine + adenine + epoxyqueuosine(34) in tRNA.
  • The reaction is a combined transfer and isomerization of the ribose moiety of S-adenosyl-L-methionine to the modified guanosine base in the wobble position in tRNAs specific for Tyr, His, Asp or Asn.
  • It is part of the queuosine biosynthesis pathway.
 147 A0A077MX05 A0A077NJC4 A0A077NXN5 A0A077P127 A0A077PLU3 A0A077PTE3 A0A077QI12 A0A084A5K3 A0A085HHL8 A0A085JAV4
(137 more...)