The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 5429: U6 snRNA-associated Sm-like protein LSm1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 12 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
4 O15116 (/IPI) P47017 (/IPI) Q8LFL8 (/IPI) Q945P8 (/IPI)
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
3 O15116 (/IDA) Q8LFL8 (/IDA) Q945P8 (/IDA)
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
2 P87173 (/ISO) Q8VC85 (/ISO)
MRNA binding GO:0003729
Interacting selectively and non-covalently with messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.
2 D3ZWB1 (/IDA) P47017 (/IDA)
RNA cap binding GO:0000339
Interacting selectively and non-covalently with a 7-methylguanosine (m7G) group or derivative located at the 5' end of an RNA molecule.
1 P47017 (/IGI)
RNA cap binding GO:0000339
Interacting selectively and non-covalently with a 7-methylguanosine (m7G) group or derivative located at the 5' end of an RNA molecule.
1 P47017 (/IMP)
RNA cap binding GO:0000339
Interacting selectively and non-covalently with a 7-methylguanosine (m7G) group or derivative located at the 5' end of an RNA molecule.
1 P47017 (/IPI)
RNA cap binding GO:0000339
Interacting selectively and non-covalently with a 7-methylguanosine (m7G) group or derivative located at the 5' end of an RNA molecule.
1 P87173 (/ISO)
RNA cap binding GO:0000339
Interacting selectively and non-covalently with a 7-methylguanosine (m7G) group or derivative located at the 5' end of an RNA molecule.
1 Q54W83 (/ISS)
Chromatin binding GO:0003682
Interacting selectively and non-covalently with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.
1 P47017 (/IDA)
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
1 Q54W83 (/ISS)
Pre-mRNA binding GO:0036002
Interacting selectively and non-covalently with pre-messenger RNA (pre-mRNA), an intermediate molecule between DNA and protein that may contain introns and, at least in part, encodes one or more proteins. Introns are removed from pre-mRNA to form a mRNA molecule.
1 D3ZWB1 (/IDA)

There are 26 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
MRNA processing GO:0006397
Any process involved in the conversion of a primary mRNA transcript into one or more mature mRNA(s) prior to translation into polypeptide.
2 Q8LFL8 (/IGI) Q945P8 (/IGI)
Response to water deprivation GO:0009414
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a water deprivation stimulus, prolonged deprivation of water.
2 Q8LFL8 (/IMP) Q945P8 (/IMP)
Cold acclimation GO:0009631
Any process that increases freezing tolerance of an organism in response to low, nonfreezing temperatures.
2 Q8LFL8 (/IMP) Q945P8 (/IMP)
RNA metabolic process GO:0016070
The cellular chemical reactions and pathways involving RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage.
2 Q8LFL8 (/IGI) Q945P8 (/IGI)
Hyperosmotic salinity response GO:0042538
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, an increase in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.
2 Q8LFL8 (/IMP) Q945P8 (/IMP)
Histone mRNA catabolic process GO:0071044
The chemical reactions and pathways resulting in the breakdown of histone messenger RNA (mRNA).
2 Q5E9Z8 (/ISS) Q8VC85 (/ISS)
Nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288
A major pathway of degradation of nuclear-transcribed mRNAs that proceeds through a series of ordered steps that includes poly(A) tail shortening and that can regulate mRNA stability.
1 P47017 (/IGI)
Nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288
A major pathway of degradation of nuclear-transcribed mRNAs that proceeds through a series of ordered steps that includes poly(A) tail shortening and that can regulate mRNA stability.
1 P47017 (/IMP)
Nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288
A major pathway of degradation of nuclear-transcribed mRNAs that proceeds through a series of ordered steps that includes poly(A) tail shortening and that can regulate mRNA stability.
1 P87173 (/ISO)
Deadenylation-dependent decapping of nuclear-transcribed mRNA GO:0000290
Cleavage of the 5'-cap of a nuclear mRNA triggered by shortening of the poly(A) tail to below a minimum functional length.
1 P47017 (/IGI)
Deadenylation-dependent decapping of nuclear-transcribed mRNA GO:0000290
Cleavage of the 5'-cap of a nuclear mRNA triggered by shortening of the poly(A) tail to below a minimum functional length.
1 P47017 (/IMP)
Deadenylation-dependent decapping of nuclear-transcribed mRNA GO:0000290
Cleavage of the 5'-cap of a nuclear mRNA triggered by shortening of the poly(A) tail to below a minimum functional length.
1 P47017 (/IPI)
Deadenylation-dependent decapping of nuclear-transcribed mRNA GO:0000290
Cleavage of the 5'-cap of a nuclear mRNA triggered by shortening of the poly(A) tail to below a minimum functional length.
1 P87173 (/ISO)
RNA splicing, via transesterification reactions GO:0000375
Splicing of RNA via a series of two transesterification reactions.
1 O15116 (/TAS)
MRNA splicing, via spliceosome GO:0000398
The joining together of exons from one or more primary transcripts of messenger RNA (mRNA) and the excision of intron sequences, via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced.
1 Q9W2K2 (/ISS)
RNA processing GO:0006396
Any process involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules.
1 Q9W2K2 (/ISS)
RNA processing GO:0006396
Any process involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules.
1 P87173 (/NAS)
MRNA processing GO:0006397
Any process involved in the conversion of a primary mRNA transcript into one or more mature mRNA(s) prior to translation into polypeptide.
1 O15116 (/TAS)
MRNA catabolic process GO:0006402
The chemical reactions and pathways resulting in the breakdown of mRNA, messenger RNA, which is responsible for carrying the coded genetic 'message', transcribed from DNA, to sites of protein assembly at the ribosomes.
1 Q54W83 (/ISS)
RNA splicing GO:0008380
The process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA.
1 O15116 (/TAS)
Stem cell population maintenance GO:0019827
The process by which an organism or tissue maintains a population of stem cells of a single type. This can be achieved by a number of mechanisms: stem cell asymmetric division maintains stem cell numbers; stem cell symmetric division increases them; maintenance of a stem cell niche maintains the conditions for commitment to the stem cell fate for some types of stem cell; stem cells may arise de novo from other cell types.
1 Q8VC85 (/IMP)
Cytoplasmic mRNA processing body assembly GO:0033962
The aggregation, arrangement and bonding together of proteins and RNA molecules to form a cytoplasmic mRNA processing body.
1 Q9W2K2 (/IMP)
Exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay GO:0043928
The chemical reactions and pathways resulting in the breakdown of the transcript body of a nuclear-transcribed mRNA that occurs when the ends are not protected by the 3'-poly(A) tail.
1 O15116 (/TAS)
Negative regulation of neuron differentiation GO:0045665
Any process that stops, prevents, or reduces the frequency, rate or extent of neuron differentiation.
1 Q8VC85 (/IMP)
Histone mRNA catabolic process GO:0071044
The chemical reactions and pathways resulting in the breakdown of histone messenger RNA (mRNA).
1 O15116 (/IMP)
Histone mRNA catabolic process GO:0071044
The chemical reactions and pathways resulting in the breakdown of histone messenger RNA (mRNA).
1 Q8VC85 (/ISO)

There are 19 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
P-body GO:0000932
A focus in the cytoplasm where mRNAs may become inactivated by decapping or some other mechanism. Protein and RNA localized to these foci are involved in mRNA degradation, nonsense-mediated mRNA decay (NMD), translational repression, and RNA-mediated gene silencing.
5 P47017 (/IDA) Q20229 (/IDA) Q8LFL8 (/IDA) Q8VC85 (/IDA) Q945P8 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
3 O15116 (/IDA) P47017 (/IDA) P87173 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
3 O15116 (/IDA) P47017 (/IDA) Q20229 (/IDA)
P-body GO:0000932
A focus in the cytoplasm where mRNAs may become inactivated by decapping or some other mechanism. Protein and RNA localized to these foci are involved in mRNA degradation, nonsense-mediated mRNA decay (NMD), translational repression, and RNA-mediated gene silencing.
1 P47017 (/IMP)
P-body GO:0000932
A focus in the cytoplasm where mRNAs may become inactivated by decapping or some other mechanism. Protein and RNA localized to these foci are involved in mRNA degradation, nonsense-mediated mRNA decay (NMD), translational repression, and RNA-mediated gene silencing.
1 P87173 (/ISO)
P-body GO:0000932
A focus in the cytoplasm where mRNAs may become inactivated by decapping or some other mechanism. Protein and RNA localized to these foci are involved in mRNA degradation, nonsense-mediated mRNA decay (NMD), translational repression, and RNA-mediated gene silencing.
1 Q54W83 (/ISS)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q8VC85 (/ISS)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 O15116 (/TAS)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q8VC85 (/ISS)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 P87173 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 O15116 (/TAS)
MRNA cap binding complex GO:0005845
Any protein complex that binds to an mRNA cap at any time in the lifetime of the mRNA.
1 P47017 (/IPI)
MRNA cap binding complex GO:0005845
Any protein complex that binds to an mRNA cap at any time in the lifetime of the mRNA.
1 P87173 (/ISO)
Cytoplasmic stress granule GO:0010494
A dense aggregation in the cytosol composed of proteins and RNAs that appear when the cell is under stress.
1 Q20229 (/IDA)
Axon GO:0030424
The long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminals and varicosities, which are sites of storage and release of neurotransmitter.
1 D3ZWB1 (/IDA)
Dendrite GO:0030425
A neuron projection that has a short, tapering, often branched, morphology, receives and integrates signals from other neurons or from sensory stimuli, and conducts a nerve impulse towards the axon or the cell body. In most neurons, the impulse is conveyed from dendrites to axon via the cell body, but in some types of unipolar neuron, the impulse does not travel via the cell body.
1 D3ZWB1 (/IDA)
Neuronal cell body GO:0043025
The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites.
1 D3ZWB1 (/IDA)
Messenger ribonucleoprotein complex GO:1990124
A ribonucleoprotein complex containing both protein and messenger RNA (mRNA) molecules.
1 D3ZWB1 (/IDA)
Lsm1-7-Pat1 complex GO:1990726
A conserved protein complex that plays an important role in coupling deadenylation and decapping in the 5'-to-3' mRNA decay pathway. An example is found in S. cerevisiae.
1 P47017 (/IDA)
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