An Fc-gamma receptor signaling pathway that contributes to the endocytic engulfment of external particulate material by phagocytes.

The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a thrombocyte, a nucleated cell found in all vertebrates but mammals involved in hemostasis.

The process whose specific outcome is the progression of the myeloid and lymphoid derived organ/tissue systems of the blood and other parts of the body over time, from formation to the mature structure. The site of hemopoiesis is variable during development, but occurs primarily in bone marrow or kidney in many adult vertebrates.

The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of any cell of the myeloid leukocyte, megakaryocyte, thrombocyte, or erythrocyte lineages.

The process in which a relatively unspecialized monocyte acquires the specialized features of a macrophage.

The process in which the anatomical structures of a dendritic spine are generated and organized. A dendritic spine is a protrusion from a dendrite and a specialized subcellular compartment involved in synaptic transmission.

The aggregation, arrangement and bonding together of a set of components to form a protein complex.

A vesicle-mediated transport process in which cells take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle.

The evagination of a membrane, resulting in formation of a vesicle.

Assembly or disassembly of actin filaments by the addition or removal of actin monomers from a filament.

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a vesicle.

Movement of a vesicle along an actin filament, mediated by motor proteins.

The directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding.

The movement of a leukocyte in response to an external stimulus.

The initial step in the formation of an actin filament, in which actin monomers combine to form a new filament. Nucleation is slow relative to the subsequent addition of more monomers to extend the filament.

The series of molecular signals generated as a consequence of an ephrin receptor binding to an ephrin.

The movement of a macrophage in response to an external stimulus.

Any process that activates or increases the frequency, rate or extent of the assembly of a filopodium, a thin, stiff protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal growth cone.

Any process that modulates the frequency, rate or extent of neutrophil migration.

Any process that activates or increases the frequency, rate or extent of clathrin-mediated endocytosis.

The aggregation, arrangement and bonding together of constituent RNAs and proteins to form the small ribosomal subunit.

Assembly of an actin cortical patch, a discrete actin-containing structure found at the plasma membrane of fungal cells.

Any process that modulates the frequency, rate, or extent of T cell antigen processing and presentation.

Any process that modulates the frequency, rate, or extent of T cell antigen processing and presentation.

The evagination of a membrane, resulting in formation of a vesicle.

The directed, self-propelled movement of a cell or subcellular component without the involvement of an external agent such as a transporter or a pore.

Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack.

Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat.

Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat.

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments. Includes processes that control the spatial distribution of actin filaments, such as organizing filaments into meshworks, bundles, or other structures, as by cross-linking.

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a vacuole.

The sequential process in which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot; it may be divided into three stages: stage 1, the formation of intrinsic and extrinsic prothrombin converting principle; stage 2, the formation of thrombin; stage 3, the formation of stable fibrin polymers.

Any process that modulates the frequency, rate or extent of the assembly or disassembly of actin filaments by the addition or removal of actin monomers from a filament.

Any process that modulates the frequency, rate or extent of the assembly or disassembly of actin filaments by the addition or removal of actin monomers from a filament.

Assembly or disassembly of actin filaments by the addition or removal of actin monomers from a filament.

The process whose specific outcome is the progression of the epidermis over time, from its formation to the mature structure. The epidermis is the outer epithelial layer of an animal, it may be a single layer that produces an extracellular material (e.g. the cuticle of arthropods) or a complex stratified squamous epithelium, as in the case of many vertebrate species.

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of nourishment.

The set of specific processes that generate the ability of an organism to induce an abnormal, generally detrimental state in another organism.

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a bacterium.

The infolding of a membrane.

Any process that modulates the rate, frequency or extent of the formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell.

Any process that modulates the rate, frequency or extent of the formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell.

The orderly movement of an epithelial cell from one site to another, often during the development of a multicellular organism.

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a vesicle.

The directed movement of substances into, out of, or mediated by an endosome, a membrane-bounded organelle that carries materials newly ingested by endocytosis. It passes many of the materials to lysosomes for degradation.

The process in which the anatomical structures of embryonic epithelia are generated and organized.

The specification and formation of anisotropic intracellular organization or cell growth patterns.

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins.

Assembly of actin filaments by the addition of actin monomers to a filament.

Assembly of actin filaments by the addition of actin monomers to a filament.

Movement of organelles or other particles along actin filaments, or sliding of actin filaments past each other, mediated by motor proteins.

Movement of a vesicle along an actin filament, mediated by motor proteins.

The process in which a multicellular organism, a unicellular organism or a group of unicellular organisms grow in a threadlike, filamentous shape.

Any process that activates or increases the frequency, rate or extent of actin polymerization.

Any cellular process that results in the specification, formation or maintenance of polarized actin-based cytoskeletal structures.

Any process that affects the structure and integrity of a protein, altering the likelihood of its degradation or aggregation.

Any process that activates or increases the frequency, rate or extent of the assembly of actin filament bundles.

A series of molecular signals within the cell that are mediated by the Cdc42 protein switching to a GTP-bound active state.

A series of molecular signals within the cell that are mediated by the Cdc42 protein switching to a GTP-bound active state.

Any process that modulates the frequency, rate or extent of any process in which a protein is transported to, or maintained in, a specific location.

Any process that modulates the frequency, rate or extent of actin nucleation mediated by the Arp2/3 complex and interacting proteins.

A protein complex localization process that takes place at the cellular level; as a result, a protein complex is transported to, or maintained in, a specific location within a cell.

The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to deprivation of nourishment.

The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to a biotic (living) stimulus.

The change in morphology and behavior of a mature or immature T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.

The process in which a group of unicellular organisms grow in a threadlike, filamentous shape.

A process of actin cortical patch localization in which the patch moves from the cell surface to the inside of the cell.

The initial step in the formation of an actin filament, in which actin monomers combine to form a new filament. Nucleation is slow relative to the subsequent addition of more monomers to extend the filament.

The initial step in the formation of an actin filament, in which actin monomers combine to form a new filament. Nucleation is slow relative to the subsequent addition of more monomers to extend the filament.

A series of molecular signals initiated by the cross-linking of an antigen receptor on a T cell.

Any process that modulates the activity of the enzyme nitric-oxide synthase.

Any process that activates or increases the frequency, rate or extent of the assembly of a filopodium, a thin, stiff protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal growth cone.

Any process that modulates the frequency, rate or extent of the assembly of a stress fiber, a bundle of microfilaments and other proteins found in fibroblasts.

Any process that modulates the frequency, rate or extent of the assembly of a stress fiber, a bundle of microfilaments and other proteins found in fibroblasts.

Any process that stops, prevents, or reduces the frequency, rate or extent of the assembly a stress fiber, a bundle of microfilaments and other proteins found in fibroblasts.

Any process that stops, prevents, or reduces the frequency, rate or extent of the assembly a stress fiber, a bundle of microfilaments and other proteins found in fibroblasts.

Any process in which is the spindle is transported to, and/or maintained in, a specific location.

Any process in which actin cortical patches are transported to, or maintained in, a specific location. An actin cortical patch is a discrete actin-containing structure found just beneath the plasma membrane in fungal cells.

Any process in which actin cortical patches are transported to, or maintained in, a specific location. An actin cortical patch is a discrete actin-containing structure found just beneath the plasma membrane in fungal cells.

The process in which the anatomical structures of a dendritic spine are generated and organized. A dendritic spine is a protrusion from a dendrite and a specialized subcellular compartment involved in synaptic transmission.

A process which results in the assembly, arrangement of constituent parts, or disassembly of a membrane. A membrane is a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

Any cellular process that results in the specification, formation or maintenance of a polarized intracellular organization or cell growth patterns that regulate the shape of a cell.

A membrane tubulation process occurring in a plasma membrane.

Any actomyosin contractile ring contraction that is involved in mitotic cell cycle.

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one stimulus.

Any actomyosin contractile ring assembly that is involved in mitotic cytokinesis.

Any process that stops, prevents or reduces the frequency, rate or extent of membrane tubulation.

Any process that stops, prevents, or reduces the frequency, rate or extent of cell motility.

Any process that stops, prevents, or reduces the frequency, rate or extent of cell motility.

Any process that activates or increases the frequency, rate or extent of clathrin-mediated endocytosis.

Any process that stops, prevents or reduces the frequency, rate or extent of lymphocyte migration.

Any process that activates or increases the frequency, rate or extent of Arp2/3 complex-mediated actin nucleation.

The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

An endocytic patch that consists of an actin-containing structure found at the plasma membrane in cells; formed of networks of branched actin filaments that lie just beneath the plasma membrane and assemble, move, and disassemble rapidly. An example of this is the actin cortical patch found in Saccharomyces cerevisiae.

The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

The part of the cytoskeleton (the internal framework of a cell) composed of actin and associated proteins. Includes actin cytoskeleton-associated complexes.

The area of a motile cell closest to the direction of movement.

A vesicle found in the cytoplasm of a cell.

A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.

The lipid bilayer surrounding any of the compartments of the Golgi apparatus.

The end, or tip, of a fungal hypha, where polarized growth occurs during hyphal elongation.

All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

A cytoskeletal structure composed of actin filaments and myosin that forms beneath the plasma membrane of many cells, including animal cells and yeast cells, in a plane perpendicular to the axis of the spindle, i.e. the cell division plane. Ring contraction is associated with centripetal growth of the membrane that divides the cytoplasm of the two daughter cells. In animal cells, the contractile ring is located inside the plasma membrane at the location of the cleavage furrow. In budding fungal cells, e.g. mitotic S. cerevisiae cells, the contractile ring forms beneath the plasma membrane at the mother-bud neck before mitosis.

The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

A filamentous structure formed of a two-stranded helical polymer of the protein actin and associated proteins. Actin filaments are a major component of the contractile apparatus of skeletal muscle and the microfilaments of the cytoskeleton of eukaryotic cells. The filaments, comprising polymerized globular actin molecules, appear as flexible structures with a diameter of 5-9 nm. They are organized into a variety of linear bundles, two-dimensional networks, and three dimensional gels. In the cytoskeleton they are most highly concentrated in the cortex of the cell just beneath the plasma membrane.

A filamentous structure formed of a two-stranded helical polymer of the protein actin and associated proteins. Actin filaments are a major component of the contractile apparatus of skeletal muscle and the microfilaments of the cytoskeleton of eukaryotic cells. The filaments, comprising polymerized globular actin molecules, appear as flexible structures with a diameter of 5-9 nm. They are organized into a variety of linear bundles, two-dimensional networks, and three dimensional gels. In the cytoskeleton they are most highly concentrated in the cortex of the cell just beneath the plasma membrane.

The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

A cell junction that forms a connection between two or more cells in a multicellular organism; excludes direct cytoplasmic junctions such as ring canals.

A protuberance from a cell of an organism that reproduces by budding, which will grow larger and become a separate daughter cell after nuclear division, cytokinesis, and cell wall formation (when appropriate). The daughter cell may completely separate from the mother cell, or the mother and daughter cells may remain associated.

The region of a cell that lies just beneath the plasma membrane and often, but not always, contains a network of actin filaments and associated proteins.

The lipid bilayer surrounding any membrane-bounded vesicle in the cell.

A thin sheetlike process extended by the leading edge of a migrating cell or extending cell process; contains a dense meshwork of actin filaments.

Polarized accumulation of cytoskeletal proteins (including F-actin) and regulatory proteins in a cell. An example of this is the actin cap found in Saccharomyces cerevisiae.

An endocytic patch that consists of an actin-containing structure found at the plasma membrane in cells; formed of networks of branched actin filaments that lie just beneath the plasma membrane and assemble, move, and disassemble rapidly. An example of this is the actin cortical patch found in Saccharomyces cerevisiae.

The lipid bilayer surrounding an endocytic vesicle.

A vesicle found in the cytoplasm of a cell.

The apex of the mating projection in unicellular fungi exposed to mating pheromone; site of polarized growth.

The region at the end of the longest axis of a cylindrical or elongated cell.

A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.