CATH Superfamily 2.30.29.30

FunFam 22238: RAC-beta serine/threonine-protein kinase A

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 37 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

GO Term	Annotations	Evidence
Protein binding GO:0005515 Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).	15	A0A0B8RZS0 (/IPI) B0LPE5 (/IPI) G9BWQ2 (/IPI) O57513 (/IPI) P31749 (/IPI) P31750 (/IPI) P31751 (/IPI) P47196 (/IPI) P47197 (/IPI) Q01314 (/IPI) (5 more)
Protein serine/threonine kinase activity GO:0004674 Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.	10	P31749 (/IDA) P31750 (/IDA) P31751 (/IDA) P47196 (/IDA) P47197 (/IDA) Q17941 (/IDA) Q60823 (/IDA) Q63484 (/IDA) Q9XTG7 (/IDA) Q9Y243 (/IDA)
ATP binding GO:0005524 Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.	6	P31749 (/IDA) P31751 (/IDA) P47196 (/IDA) P47197 (/IDA) Q63484 (/IDA) Q9Y243 (/IDA)
Protein kinase activity GO:0004672 Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP.	5	P31750 (/IDA) P47196 (/IDA) Q17941 (/IDA) Q60823 (/IDA) Q9XTG7 (/IDA)
Protein serine/threonine kinase activity GO:0004674 Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.	5	P31749 (/TAS) P31750 (/TAS) P31751 (/TAS) P47196 (/TAS) P47197 (/TAS)
Protein serine/threonine kinase activity GO:0004674 Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.	4	P31750 (/ISS) P47196 (/ISS) Q01314 (/ISS) Q98TY9 (/ISS)
Protein serine/threonine kinase activity GO:0004674 Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.	3	P31750 (/ISO) Q60823 (/ISO) Q9WUA6 (/ISO)
Protein kinase C binding GO:0005080 Interacting selectively and non-covalently with protein kinase C.	3	P47196 (/IPI) P47197 (/IPI) Q63484 (/IPI)
ATP binding GO:0005524 Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.	3	P31750 (/ISO) Q60823 (/ISO) Q9WUA6 (/ISO)
Phosphatidylinositol-3,4,5-trisphosphate binding GO:0005547 Interacting selectively and non-covalently with phosphatidylinositol-3,4,5-trisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 3', 4' and 5' positions.	3	P31749 (/IDA) Q17941 (/IDA) Q9XTG7 (/IDA)
Protein kinase activity GO:0004672 Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP.	2	P31749 (/TAS) Q9Y243 (/TAS)
Protein serine/threonine kinase activity GO:0004674 Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.	2	P31749 (/EXP) Q60823 (/EXP)
Protein serine/threonine kinase activity GO:0004674 Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.	2	A0A0B8RZS0 (/IMP) G9BWQ2 (/IMP)
Protein kinase binding GO:0019901 Interacting selectively and non-covalently with a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate.	2	P31750 (/IPI) P47196 (/IPI)
Protein kinase activity GO:0004672 Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP.	1	Q9WUA6 (/ISO)
Protein serine/threonine/tyrosine kinase activity GO:0004712 Catalysis of the reactions: ATP + a protein serine = ADP + protein serine phosphate; ATP + a protein threonine = ADP + protein threonine phosphate; and ATP + a protein tyrosine = ADP + protein tyrosine phosphate.	1	P31749 (/IDA)
Protein serine/threonine/tyrosine kinase activity GO:0004712 Catalysis of the reactions: ATP + a protein serine = ADP + protein serine phosphate; ATP + a protein threonine = ADP + protein threonine phosphate; and ATP + a protein tyrosine = ADP + protein tyrosine phosphate.	1	P31750 (/ISO)
Protein tyrosine kinase activity GO:0004713 Catalysis of the reaction: ATP + a protein tyrosine = ADP + protein tyrosine phosphate.	1	P31750 (/TAS)
Calmodulin binding GO:0005516 Interacting selectively and non-covalently with calmodulin, a calcium-binding protein with many roles, both in the calcium-bound and calcium-free states.	1	Q17941 (/IDA)
Calmodulin binding GO:0005516 Interacting selectively and non-covalently with calmodulin, a calcium-binding protein with many roles, both in the calcium-bound and calcium-free states.	1	Q17941 (/IPI)
ATP binding GO:0005524 Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.	1	P31749 (/IC)
Phosphatidylinositol-3,4,5-trisphosphate binding GO:0005547 Interacting selectively and non-covalently with phosphatidylinositol-3,4,5-trisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 3', 4' and 5' positions.	1	P31750 (/ISO)
Kinase activity GO:0016301 Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.	1	P31750 (/EXP)
Kinase activity GO:0016301 Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.	1	P31749 (/IDA)
Kinase activity GO:0016301 Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.	1	P31750 (/ISO)
Enzyme binding GO:0019899 Interacting selectively and non-covalently with any enzyme.	1	P47196 (/IPI)
Enzyme binding GO:0019899 Interacting selectively and non-covalently with any enzyme.	1	P31749 (/ISS)
Nitric-oxide synthase regulator activity GO:0030235 Modulates the activity of nitric oxide synthase.	1	P31749 (/IMP)
Nitric-oxide synthase regulator activity GO:0030235 Modulates the activity of nitric oxide synthase.	1	P31750 (/ISO)
GTPase activating protein binding GO:0032794 Interacting selectively and non-covalently with a GTPase activating protein.	1	P47196 (/IPI)
Identical protein binding GO:0042802 Interacting selectively and non-covalently with an identical protein or proteins.	1	P31749 (/IPI)
Identical protein binding GO:0042802 Interacting selectively and non-covalently with an identical protein or proteins.	1	P31750 (/ISO)
Phosphatidylinositol-3,4-bisphosphate binding GO:0043325 Interacting selectively and non-covalently with phosphatidylinositol-3,4-bisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 3' and 4' positions.	1	P31749 (/IDA)
Phosphatidylinositol-3,4-bisphosphate binding GO:0043325 Interacting selectively and non-covalently with phosphatidylinositol-3,4-bisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 3' and 4' positions.	1	P31750 (/ISO)
Protein phosphatase 2A binding GO:0051721 Interacting selectively and non-covalently with the enzyme protein phosphatase 2A.	1	P47196 (/IPI)
14-3-3 protein binding GO:0071889 Interacting selectively and non-covalently with a 14-3-3 protein. A 14-3-3 protein is any of a large family of approximately 30kDa acidic proteins which exist primarily as homo- and heterodimers within all eukaryotic cells, and have been implicated in the modulation of distinct biological processes by binding to specific phosphorylated sites on diverse target proteins, thereby forcing conformational changes or influencing interactions between their targets and other molecules. Each 14-3-3 protein sequence can be roughly divided into three sections: a divergent amino terminus, the conserved core region and a divergent carboxyl terminus. The conserved middle core region of the 14-3-3s encodes an amphipathic groove that forms the main functional domain, a cradle for interacting with client proteins.	1	P31749 (/IPI)
14-3-3 protein binding GO:0071889 Interacting selectively and non-covalently with a 14-3-3 protein. A 14-3-3 protein is any of a large family of approximately 30kDa acidic proteins which exist primarily as homo- and heterodimers within all eukaryotic cells, and have been implicated in the modulation of distinct biological processes by binding to specific phosphorylated sites on diverse target proteins, thereby forcing conformational changes or influencing interactions between their targets and other molecules. Each 14-3-3 protein sequence can be roughly divided into three sections: a divergent amino terminus, the conserved core region and a divergent carboxyl terminus. The conserved middle core region of the 14-3-3s encodes an amphipathic groove that forms the main functional domain, a cradle for interacting with client proteins.	1	P31750 (/ISO)

There are 273 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

GO Term	Annotations	Evidence
Response to growth hormone GO:0060416 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth hormone stimulus. Growth hormone is a peptide hormone that binds to the growth hormone receptor and stimulates growth.	41	B0LPE5 (/ISS) C5IJA6 (/ISS) D9IA52 (/ISS) E2RJX4 (/ISS) F1NMS0 (/ISS) F6QP11 (/ISS) F6SAS5 (/ISS) F6WGH2 (/ISS) G1KLB6 (/ISS) G1LMQ4 (/ISS) (31 more)
Response to insulin-like growth factor stimulus GO:1990418 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin-like growth factor stimulus.	41	B0LPE5 (/ISS) C5IJA6 (/ISS) D9IA52 (/ISS) E2RJX4 (/ISS) F1NMS0 (/ISS) F6QP11 (/ISS) F6SAS5 (/ISS) F6WGH2 (/ISS) G1KLB6 (/ISS) G1LMQ4 (/ISS) (31 more)
Protein phosphorylation GO:0006468 The process of introducing a phosphate group on to a protein.	8	P31749 (/IDA) P31750 (/IDA) P47196 (/IDA) P47197 (/IDA) Q17941 (/IDA) Q60823 (/IDA) Q63484 (/IDA) Q9XTG7 (/IDA)
Insulin receptor signaling pathway GO:0008286 The series of molecular signals generated as a consequence of the insulin receptor binding to insulin.	6	P31749 (/IMP) P31750 (/IMP) P31751 (/IMP) P47196 (/IMP) Q17941 (/IMP) Q9XTG7 (/IMP)
Cellular response to insulin stimulus GO:0032869 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms.	6	P31749 (/IMP) P31750 (/IMP) P31751 (/IMP) P47196 (/IMP) P47197 (/IMP) Q63484 (/IMP)
Peptidyl-serine phosphorylation GO:0018105 The phosphorylation of peptidyl-serine to form peptidyl-O-phospho-L-serine.	5	P31749 (/IDA) P31750 (/IDA) P47196 (/IDA) Q17941 (/IDA) Q9XTG7 (/IDA)
Positive regulation of glucose import GO:0046326 Any process that activates or increases the frequency, rate or extent of the import of the hexose monosaccharide glucose into a cell or organelle.	5	E7EYV0 (/IMP) P31749 (/IMP) P31751 (/IMP) P47197 (/IMP) Q8UUX0 (/IMP)
Positive regulation of endothelial cell proliferation GO:0001938 Any process that activates or increases the rate or extent of endothelial cell proliferation.	4	P31750 (/ISS) P47196 (/ISS) Q01314 (/ISS) Q98TY9 (/ISS)
Positive regulation of sodium ion transport GO:0010765 Any process that increases the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	4	P31750 (/IMP) P47196 (/IMP) P47197 (/IMP) Q63484 (/IMP)
Regulation of neuron projection development GO:0010975 Any process that modulates the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).	4	P31749 (/ISS) P47196 (/ISS) Q01314 (/ISS) Q98TY9 (/ISS)
Positive regulation of vesicle fusion GO:0031340 Any process that activates or increases the frequency, rate or extent of vesicle fusion.	4	P31751 (/ISS) P47197 (/ISS) Q6IP76 (/ISS) Q7ZX15 (/ISS)
Negative regulation of apoptotic process GO:0043066 Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.	4	E7EYV0 (/IMP) P31750 (/IMP) P47197 (/IMP) Q8UUX0 (/IMP)
Negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GO:0043154 Any process that stops, prevents, or reduces the frequency, rate or extent of a cysteine-type endopeptidase activity involved in the apoptotic process.	4	P31749 (/ISS) P47196 (/ISS) Q01314 (/ISS) Q98TY9 (/ISS)
Phosphatidylinositol-mediated signaling GO:0048015 A series of molecular signals in which a cell uses a phosphatidylinositol-mediated signaling to convert a signal into a response. Phosphatidylinositols include phosphatidylinositol (PtdIns) and its phosphorylated derivatives.	4	P31749 (/TAS) P47196 (/TAS) P47197 (/TAS) Q63484 (/TAS)
Intracellular protein transmembrane transport GO:0065002 The directed movement of proteins in a cell, from one side of a membrane to another by means of some agent such as a transporter or pore.	4	P31751 (/ISS) P47197 (/ISS) Q6IP76 (/ISS) Q7ZX15 (/ISS)
Negative regulation of release of cytochrome c from mitochondria GO:0090201 Any process that decreases the rate, frequency or extent of release of cytochrome c from mitochondria, the process in which cytochrome c is enabled to move from the mitochondrial intermembrane space into the cytosol, which is an early step in apoptosis and leads to caspase activation.	4	P31749 (/ISS) P47196 (/ISS) Q01314 (/ISS) Q98TY9 (/ISS)
Positive regulation of protein targeting to membrane GO:0090314 Any process that increases the frequency, rate or extent of the process of directing proteins towards a membrane, usually using signals contained within the protein.	4	P31751 (/ISS) P47197 (/ISS) Q6IP76 (/ISS) Q7ZX15 (/ISS)
Positive regulation of protein phosphorylation GO:0001934 Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to amino acids within a protein.	3	P31751 (/ISS) Q6IP76 (/ISS) Q7ZX15 (/ISS)
Protein phosphorylation GO:0006468 The process of introducing a phosphate group on to a protein.	3	P47196 (/ISS) Q01314 (/ISS) Q98TY9 (/ISS)
Response to oxidative stress GO:0006979 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.	3	P31749 (/ISS) P31750 (/ISS) P47196 (/ISS)
Signal transduction GO:0007165 The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.	3	P31749 (/TAS) P31751 (/TAS) Q9Y243 (/TAS)
Insulin receptor signaling pathway GO:0008286 The series of molecular signals generated as a consequence of the insulin receptor binding to insulin.	3	P31750 (/ISS) P47196 (/ISS) Q98TY9 (/ISS)
Positive regulation of sodium ion transport GO:0010765 Any process that increases the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	3	P31750 (/ISO) Q60823 (/ISO) Q9WUA6 (/ISO)
Peptidyl-threonine phosphorylation GO:0018107 The phosphorylation of peptidyl-threonine to form peptidyl-O-phospho-L-threonine.	3	P31749 (/IDA) Q17941 (/IDA) Q9XTG7 (/IDA)
Cellular response to insulin stimulus GO:0032869 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms.	3	P31750 (/ISO) Q60823 (/ISO) Q9WUA6 (/ISO)
Cellular response to insulin stimulus GO:0032869 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms.	3	P31749 (/ISS) Q6IP76 (/ISS) Q7ZX15 (/ISS)
Insulin-like growth factor receptor signaling pathway GO:0048009 The series of molecular signals generated as a consequence of the insulin-like growth factor receptor binding to one of its physiological ligands.	3	P31750 (/ISS) P47196 (/ISS) Q98TY9 (/ISS)
Membrane organization GO:0061024 A process which results in the assembly, arrangement of constituent parts, or disassembly of a membrane. A membrane is a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.	3	P31749 (/TAS) P31750 (/TAS) Q60823 (/TAS)
Positive regulation of protein phosphorylation GO:0001934 Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to amino acids within a protein.	2	P31749 (/IDA) Q60823 (/IDA)
Glucose metabolic process GO:0006006 The chemical reactions and pathways involving glucose, the aldohexose gluco-hexose. D-glucose is dextrorotatory and is sometimes known as dextrose; it is an important source of energy for living organisms and is found free as well as combined in homo- and hetero-oligosaccharides and polysaccharides.	2	P31750 (/IMP) Q60823 (/IMP)
Cellular protein modification process GO:0006464 The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications) occurring at the level of an individual cell. Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification).	2	P31749 (/TAS) P31751 (/TAS)
Protein phosphorylation GO:0006468 The process of introducing a phosphate group on to a protein.	2	P47197 (/TAS) Q9Y243 (/TAS)
Insulin receptor signaling pathway GO:0008286 The series of molecular signals generated as a consequence of the insulin receptor binding to insulin.	2	P31750 (/ISO) Q60823 (/ISO)
Determination of adult lifespan GO:0008340 The control of viability and duration in the adult phase of the life-cycle.	2	Q17941 (/IMP) Q9XTG7 (/IMP)
Regulation of synaptic growth at neuromuscular junction GO:0008582 Any process that modulates the frequency, rate or extent of synaptic growth at neuromuscular junctions.	2	Q17941 (/IGI) Q9XTG7 (/IGI)
Negative regulation of plasma membrane long-chain fatty acid transport GO:0010748 Any process that decreases the rate, frequency or extent of plasma membrane long-chain fatty acid transport. Plasma membrane long-chain fatty acid transport is the directed movement of long-chain fatty acids across the plasma membrane.	2	P31749 (/IMP) P31751 (/IMP)
Negative regulation of plasma membrane long-chain fatty acid transport GO:0010748 Any process that decreases the rate, frequency or extent of plasma membrane long-chain fatty acid transport. Plasma membrane long-chain fatty acid transport is the directed movement of long-chain fatty acids across the plasma membrane.	2	P31750 (/ISO) Q60823 (/ISO)
Positive regulation of glucose metabolic process GO:0010907 Any process that increases the rate, frequency or extent of glucose metabolism. Glucose metabolic processes are the chemical reactions and pathways involving glucose, the aldohexose gluco-hexose.	2	P31749 (/IMP) P31751 (/IMP)
Positive regulation of glucose metabolic process GO:0010907 Any process that increases the rate, frequency or extent of glucose metabolism. Glucose metabolic processes are the chemical reactions and pathways involving glucose, the aldohexose gluco-hexose.	2	P31750 (/ISO) Q60823 (/ISO)
Phosphorylation GO:0016310 The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide.	2	P47196 (/ISS) Q01314 (/ISS)
Peptidyl-serine phosphorylation GO:0018105 The phosphorylation of peptidyl-serine to form peptidyl-O-phospho-L-serine.	2	P31750 (/ISO) Q9WUA6 (/ISO)
Peptidyl-threonine phosphorylation GO:0018107 The phosphorylation of peptidyl-threonine to form peptidyl-O-phospho-L-threonine.	2	P31750 (/ISO) Q9WUA6 (/ISO)
Platelet activation GO:0030168 A series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue. These events include shape change, adhesiveness, aggregation, and release reactions. When carried through to completion, these events lead to the formation of a stable hemostatic plug.	2	P31749 (/TAS) P47196 (/TAS)
Positive regulation of cell growth GO:0030307 Any process that activates or increases the frequency, rate, extent or direction of cell growth.	2	P31749 (/IDA) P47196 (/IDA)
Regulation of cell migration GO:0030334 Any process that modulates the frequency, rate or extent of cell migration.	2	P31749 (/IMP) P47196 (/IMP)
Regulation of cell migration GO:0030334 Any process that modulates the frequency, rate or extent of cell migration.	2	P31750 (/ISS) Q01314 (/ISS)
Regulation of cell migration GO:0030334 Any process that modulates the frequency, rate or extent of cell migration.	2	P31749 (/TAS) P31751 (/TAS)
Peripheral nervous system myelin maintenance GO:0032287 The process in which the structure and material content of mature peripheral nervous system myelin is kept in a functional state.	2	P31750 (/IMP) Q60823 (/IMP)
Cellular response to insulin stimulus GO:0032869 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms.	2	P31750 (/IDA) Q60823 (/IDA)
Positive regulation of nitric oxide biosynthetic process GO:0045429 Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nitric oxide.	2	P31749 (/IMP) P47197 (/IMP)
Positive regulation of glycogen biosynthetic process GO:0045725 Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glycogen.	2	P31749 (/IMP) P31751 (/IMP)
Positive regulation of glycogen biosynthetic process GO:0045725 Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glycogen.	2	P31750 (/ISO) Q60823 (/ISO)
Positive regulation of glucose import GO:0046326 Any process that activates or increases the frequency, rate or extent of the import of the hexose monosaccharide glucose into a cell or organelle.	2	P31750 (/ISO) Q60823 (/ISO)
Response to growth hormone GO:0060416 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth hormone stimulus. Growth hormone is a peptide hormone that binds to the growth hormone receptor and stimulates growth.	2	G3X7B5 (/IDA) Q01314 (/IDA)
Mammary gland epithelial cell differentiation GO:0060644 The process in which a relatively unspecialized epithelial cell becomes a more specialized epithelial cell of the mammary gland.	2	P31749 (/TAS) P31751 (/TAS)
Cellular response to organic cyclic compound GO:0071407 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus.	2	P47196 (/IDA) P47197 (/IDA)
Positive regulation of adipose tissue development GO:1904179 Any process that activates or increases the frequency, rate or extent of adipose tissue development.	2	A0A0B8RZS0 (/IMP) G9BWQ2 (/IMP)
Response to insulin-like growth factor stimulus GO:1990418 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin-like growth factor stimulus.	2	G3X7B5 (/IDA) Q01314 (/IDA)
Mitochondrial genome maintenance GO:0000002 The maintenance of the structure and integrity of the mitochondrial genome; includes replication and segregation of the mitochondrial chromosome.	1	Q9Y243 (/IMP)
Mitochondrial genome maintenance GO:0000002 The maintenance of the structure and integrity of the mitochondrial genome; includes replication and segregation of the mitochondrial chromosome.	1	Q9WUA6 (/ISO)
Protein import into nucleus, translocation GO:0000060 A protein transport process that contributes to protein import into the nucleus, and that results in the vectorial transfer of a cargo-carrier protein complex through the nuclear pore complex from the cytoplasmic side to the nucleoplasmic side of the nuclear envelope.	1	P31749 (/IMP)
Protein import into nucleus, translocation GO:0000060 A protein transport process that contributes to protein import into the nucleus, and that results in the vectorial transfer of a cargo-carrier protein complex through the nuclear pore complex from the cytoplasmic side to the nucleoplasmic side of the nuclear envelope.	1	P31750 (/ISO)
G1/S transition of mitotic cell cycle GO:0000082 The mitotic cell cycle transition by which a cell in G1 commits to S phase. The process begins with the build up of G1 cyclin-dependent kinase (G1 CDK), resulting in the activation of transcription of G1 cyclins. The process ends with the positive feedback of the G1 cyclins on the G1 CDK which commits the cell to S phase, in which DNA replication is initiated.	1	P31749 (/TAS)
Osteoblast differentiation GO:0001649 The process whereby a relatively unspecialized cell acquires the specialized features of an osteoblast, a mesodermal or neural crest cell that gives rise to bone.	1	P31750 (/IGI)
Maternal placenta development GO:0001893 Maternally driven process whose specific outcome is the progression of the placenta over time, from its formation to the mature structure. The placenta is an organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin.	1	P31750 (/IMP)
Positive regulation of protein phosphorylation GO:0001934 Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to amino acids within a protein.	1	P47197 (/IMP)
Positive regulation of protein phosphorylation GO:0001934 Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to amino acids within a protein.	1	P31750 (/ISO)
Positive regulation of endothelial cell proliferation GO:0001938 Any process that activates or increases the rate or extent of endothelial cell proliferation.	1	P31749 (/IMP)
Positive regulation of endothelial cell proliferation GO:0001938 Any process that activates or increases the rate or extent of endothelial cell proliferation.	1	P31750 (/ISO)
Glycogen metabolic process GO:0005977 The chemical reactions and pathways involving glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues in alpha-(1->4) glycosidic linkage, joined together by alpha-(1->6) glycosidic linkages.	1	P31750 (/IMP)
Glycogen biosynthetic process GO:0005978 The chemical reactions and pathways resulting in the formation of glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues.	1	P47196 (/IMP)
Regulation of glycogen biosynthetic process GO:0005979 Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glycogen.	1	P31749 (/IMP)
Regulation of glycogen biosynthetic process GO:0005979 Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glycogen.	1	P31750 (/ISO)
Translation GO:0006412 The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA. Translation ends with the release of a polypeptide chain from the ribosome.	1	P47196 (/IMP)
Protein phosphorylation GO:0006468 The process of introducing a phosphate group on to a protein.	1	P31750 (/ISO)
Negative regulation of protein kinase activity GO:0006469 Any process that stops, prevents, or reduces the frequency, rate or extent of protein kinase activity.	1	P47196 (/IDA)
Negative regulation of protein kinase activity GO:0006469 Any process that stops, prevents, or reduces the frequency, rate or extent of protein kinase activity.	1	P31749 (/IMP)
Negative regulation of protein kinase activity GO:0006469 Any process that stops, prevents, or reduces the frequency, rate or extent of protein kinase activity.	1	P31750 (/ISO)
Negative regulation of protein kinase activity GO:0006469 Any process that stops, prevents, or reduces the frequency, rate or extent of protein kinase activity.	1	P31749 (/ISS)
Nitric oxide biosynthetic process GO:0006809 The chemical reactions and pathways resulting in the formation of nitric oxide, nitrogen monoxide (NO), a colorless gas only slightly soluble in water.	1	P31749 (/TAS)
Activation-induced cell death of T cells GO:0006924 A T cell apoptotic process that occurs towards the end of the expansion phase following the initial activation of mature T cells by antigen and is triggered by T cell receptor stimulation and signals transmitted via various surface-expressed members of the TNF receptor family such as Fas ligand, Fas, and TNF and the p55 and p75 TNF receptors.	1	P31749 (/IMP)
Activation-induced cell death of T cells GO:0006924 A T cell apoptotic process that occurs towards the end of the expansion phase following the initial activation of mature T cells by antigen and is triggered by T cell receptor stimulation and signals transmitted via various surface-expressed members of the TNF receptor family such as Fas ligand, Fas, and TNF and the p55 and p75 TNF receptors.	1	P31750 (/ISO)
Chemotaxis GO:0006935 The directed movement of a motile cell or organism, or the directed growth of a cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).	1	Q17941 (/IGI)
Inflammatory response GO:0006954 The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages.	1	P31750 (/IDA)
Response to osmotic stress GO:0006970 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.	1	P47197 (/IEP)
Cellular response to DNA damage stimulus GO:0006974 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.	1	P47196 (/IDA)
Cytoskeleton organization GO:0007010 A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures.	1	P31750 (/TAS)
Signal transduction GO:0007165 The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.	1	P47196 (/IDA)
Signal transduction GO:0007165 The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.	1	Q9Y243 (/IMP)
Signal transduction GO:0007165 The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.	1	Q9WUA6 (/ISO)
G-protein coupled receptor signaling pathway GO:0007186 A series of molecular signals that proceeds with an activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, or for basal GPCR signaling the pathway begins with the receptor activating its G protein in the absence of an agonist, and ends with regulation of a downstream cellular process, e.g. transcription. The pathway can start from the plasma membrane, Golgi or nuclear membrane (PMID:24568158 and PMID:16902576).	1	P31749 (/TAS)
I-kappaB kinase/NF-kappaB signaling GO:0007249 The process in which a signal is passed on to downstream components within the cell through the I-kappaB-kinase (IKK)-dependent activation of NF-kappaB. The cascade begins with activation of a trimeric IKK complex (consisting of catalytic kinase subunits IKKalpha and/or IKKbeta, and the regulatory scaffold protein NEMO) and ends with the regulation of transcription of target genes by NF-kappaB. In a resting state, NF-kappaB dimers are bound to I-kappaB proteins, sequestering NF-kappaB in the cytoplasm. Phosphorylation of I-kappaB targets I-kappaB for ubiquitination and proteasomal degradation, thus releasing the NF-kappaB dimers, which can translocate to the nucleus to bind DNA and regulate transcription.	1	P31749 (/IMP)
I-kappaB kinase/NF-kappaB signaling GO:0007249 The process in which a signal is passed on to downstream components within the cell through the I-kappaB-kinase (IKK)-dependent activation of NF-kappaB. The cascade begins with activation of a trimeric IKK complex (consisting of catalytic kinase subunits IKKalpha and/or IKKbeta, and the regulatory scaffold protein NEMO) and ends with the regulation of transcription of target genes by NF-kappaB. In a resting state, NF-kappaB dimers are bound to I-kappaB proteins, sequestering NF-kappaB in the cytoplasm. Phosphorylation of I-kappaB targets I-kappaB for ubiquitination and proteasomal degradation, thus releasing the NF-kappaB dimers, which can translocate to the nucleus to bind DNA and regulate transcription.	1	P31750 (/ISO)
Germ cell development GO:0007281 The process whose specific outcome is the progression of an immature germ cell over time, from its formation to the mature structure (gamete). A germ cell is any reproductive cell in a multicellular organism.	1	P31750 (/IDA)
Aging GO:0007568 A developmental process that is a deterioration and loss of function over time. Aging includes loss of functions such as resistance to disease, homeostasis, and fertility, as well as wear and tear. Aging includes cellular senescence, but is more inclusive. May precede death and may succeed developmental maturation (GO:0021700).	1	P47196 (/IDA)
Chemosensory behavior GO:0007635 Behavior that is dependent upon the sensation of chemicals.	1	Q17941 (/IGI)
Cell proliferation GO:0008283 The multiplication or reproduction of cells, resulting in the expansion of a cell population.	1	P31749 (/TAS)
Insulin receptor signaling pathway GO:0008286 The series of molecular signals generated as a consequence of the insulin receptor binding to insulin.	1	Q60823 (/IDA)
Insulin receptor signaling pathway GO:0008286 The series of molecular signals generated as a consequence of the insulin receptor binding to insulin.	1	P31751 (/TAS)
Apoptotic mitochondrial changes GO:0008637 The morphological and physiological alterations undergone by mitochondria during apoptosis.	1	P31750 (/IDA)
Response to heat GO:0009408 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.	1	P31749 (/TAS)
Response to hormone GO:0009725 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hormone stimulus.	1	P31750 (/IDA)
Positive regulation of signal transduction GO:0009967 Any process that activates or increases the frequency, rate or extent of signal transduction.	1	P47197 (/IMP)
Response to organic substance GO:0010033 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic substance stimulus.	1	P31750 (/IDA)
Negative regulation of autophagy GO:0010507 Any process that stops, prevents, or reduces the frequency, rate or extent of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm.	1	P31749 (/IMP)
Negative regulation of autophagy GO:0010507 Any process that stops, prevents, or reduces the frequency, rate or extent of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm.	1	P31750 (/ISO)
Positive regulation of gene expression GO:0010628 Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.	1	P47197 (/IMP)
Negative regulation of gene expression GO:0010629 Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.	1	P31750 (/IDA)
Positive regulation of fibroblast migration GO:0010763 Any process that increases the rate, frequency or extent of fibroblast cell migration. Fibroblast cell migration is accomplished by extension and retraction of a pseudopodium.	1	P31750 (/IMP)
Positive regulation of sodium ion transport GO:0010765 Any process that increases the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	1	P31750 (/IDA)
Negative regulation of endopeptidase activity GO:0010951 Any process that decreases the frequency, rate or extent of endopeptidase activity, the endohydrolysis of peptide bonds within proteins.	1	P31749 (/IMP)
Negative regulation of endopeptidase activity GO:0010951 Any process that decreases the frequency, rate or extent of endopeptidase activity, the endohydrolysis of peptide bonds within proteins.	1	P31750 (/ISO)
Regulation of neuron projection development GO:0010975 Any process that modulates the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).	1	P31750 (/IDA)
Phosphatidylinositol 3-kinase signaling GO:0014065 A series of reactions within the signal-receiving cell, mediated by the intracellular phosphatidylinositol 3-kinase (PI3K). Many cell surface receptor linked signaling pathways signal through PI3K to regulate numerous cellular functions.	1	P31749 (/IMP)
Phosphatidylinositol 3-kinase signaling GO:0014065 A series of reactions within the signal-receiving cell, mediated by the intracellular phosphatidylinositol 3-kinase (PI3K). Many cell surface receptor linked signaling pathways signal through PI3K to regulate numerous cellular functions.	1	P31750 (/ISO)
Regulation of phosphatidylinositol 3-kinase signaling GO:0014066 Any process that modulates the frequency, rate or extent of signal transduction mediated by the phosphatidylinositol 3-kinase cascade.	1	P31749 (/TAS)
Response to muscle activity GO:0014850 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a muscle activity stimulus.	1	P47197 (/IEP)
Glucose transport GO:0015758 The directed movement of the hexose monosaccharide glucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	1	P31750 (/IMP)
Glucose transport GO:0015758 The directed movement of the hexose monosaccharide glucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	1	Q98TY9 (/ISS)
Negative regulation of macroautophagy GO:0016242 Any process that stops, prevents, or reduces the frequency, rate or extent of macroautophagy.	1	P31749 (/NAS)
Phosphorylation GO:0016310 The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide.	1	P31749 (/IDA)
Phosphorylation GO:0016310 The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide.	1	P31750 (/ISO)
Protein ubiquitination GO:0016567 The process in which one or more ubiquitin groups are added to a protein.	1	P31750 (/IDA)
Peptidyl-serine phosphorylation GO:0018105 The phosphorylation of peptidyl-serine to form peptidyl-O-phospho-L-serine.	1	P31749 (/TAS)
Spinal cord development GO:0021510 The process whose specific outcome is the progression of the spinal cord over time, from its formation to the mature structure. The spinal cord primarily conducts sensory and motor nerve impulses between the brain and the peripheral nervous tissues.	1	P47196 (/IDA)
Cell projection organization GO:0030030 A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a cell, e.g. a flagellum or axon.	1	P47196 (/IDA)
Cell projection organization GO:0030030 A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a cell, e.g. a flagellum or axon.	1	P31750 (/ISO)
Cell differentiation GO:0030154 The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.	1	P31749 (/TAS)
Protein catabolic process GO:0030163 The chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.	1	P31750 (/IDA)
Hyaluronan metabolic process GO:0030212 The chemical reactions and pathways involving hyaluronan, the naturally occurring anionic form of hyaluronic acid, any member of a group of glycosaminoglycans, the repeat units of which consist of beta-1,4 linked D-glucuronyl-beta-(1,3)-N-acetyl-D-glucosamine.	1	P47196 (/IEP)
Positive regulation of cell growth GO:0030307 Any process that activates or increases the frequency, rate, extent or direction of cell growth.	1	P31750 (/ISO)
Regulation of cell migration GO:0030334 Any process that modulates the frequency, rate or extent of cell migration.	1	P31750 (/ISO)
Positive regulation of cell migration GO:0030335 Any process that activates or increases the frequency, rate or extent of cell migration.	1	P31751 (/IDA)
Positive regulation of cell migration GO:0030335 Any process that activates or increases the frequency, rate or extent of cell migration.	1	P47197 (/IMP)
Positive regulation of cell migration GO:0030335 Any process that activates or increases the frequency, rate or extent of cell migration.	1	Q60823 (/ISO)
Endocrine pancreas development GO:0031018 The process whose specific outcome is the progression of the endocrine pancreas over time, from its formation to the mature structure. The endocrine pancreas is made up of islet cells that produce insulin, glucagon and somatostatin.	1	P31749 (/TAS)
T cell costimulation GO:0031295 The process of providing, via surface-bound receptor-ligand pairs, a second, antigen-independent, signal in addition to that provided by the T cell receptor to augment T cell activation.	1	P31749 (/TAS)
Positive regulation of vesicle fusion GO:0031340 Any process that activates or increases the frequency, rate or extent of vesicle fusion.	1	Q60823 (/IMP)
Regulation of myelination GO:0031641 Any process that modulates the frequency, rate or extent of the formation of a myelin sheath around nerve axons.	1	P31750 (/IMP)
Positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle GO:0031659 Any process that activates or increases the frequency, rate or extent of cyclin-dependent protein serine/threonine kinase activity contributing to the G1/S transition of the cell cycle.	1	P31749 (/IDA)
Positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle GO:0031659 Any process that activates or increases the frequency, rate or extent of cyclin-dependent protein serine/threonine kinase activity contributing to the G1/S transition of the cell cycle.	1	P31750 (/ISO)
Lipopolysaccharide-mediated signaling pathway GO:0031663 A series of molecular signals initiated by the binding of a lipopolysaccharide (LPS) to a receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription. Lipopolysaccharides are major components of the outer membrane of Gram-negative bacteria, making them prime targets for recognition by the immune system.	1	P31750 (/IDA)
Response to nutrient levels GO:0031667 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of nutrients.	1	P47197 (/IEP)
TOR signaling GO:0031929 A series of molecular signals mediated by TOR (Target of rapamycin) proteins, members of the phosphoinositide (PI) 3-kinase related kinase (PIKK) family that act as serine/threonine kinases in response to nutrient availability or growth factors.	1	P31749 (/NAS)
Negative regulation of fatty acid beta-oxidation GO:0031999 Any process that stops, prevents, or reduces the frequency, rate or extent of fatty acid beta-oxidation.	1	P31749 (/IMP)
Negative regulation of fatty acid beta-oxidation GO:0031999 Any process that stops, prevents, or reduces the frequency, rate or extent of fatty acid beta-oxidation.	1	P31750 (/ISO)
Positive regulation of fatty acid beta-oxidation GO:0032000 Any process that activates or increases the frequency, rate or extent of fatty acid beta-oxidation.	1	P31751 (/IMP)
Positive regulation of fatty acid beta-oxidation GO:0032000 Any process that activates or increases the frequency, rate or extent of fatty acid beta-oxidation.	1	Q60823 (/ISO)
Positive regulation of TOR signaling GO:0032008 Any process that activates or increases the frequency, rate or extent of TOR signaling.	1	Q9WUA6 (/IMP)
Positive regulation of endodeoxyribonuclease activity GO:0032079 Any process that activates or increases the frequency, rate or extent of endodeoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid by creating internal breaks.	1	P31749 (/IDA)
Positive regulation of endodeoxyribonuclease activity GO:0032079 Any process that activates or increases the frequency, rate or extent of endodeoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid by creating internal breaks.	1	P31750 (/ISO)
Response to food GO:0032094 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a food stimulus; food is anything which, when taken into the body, serves to nourish or build up the tissues or to supply body heat.	1	P31750 (/IDA)
Positive regulation of cellular protein metabolic process GO:0032270 Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a protein, occurring at the level of an individual cell.	1	P47196 (/IMP)
Positive regulation of cellular protein metabolic process GO:0032270 Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a protein, occurring at the level of an individual cell.	1	P31749 (/ISS)
Positive regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032436 Any process that activates or increases the frequency, rate or extent of the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.	1	P31750 (/IMP)
Response to insulin GO:0032868 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms.	1	P47197 (/IDA)
Response to insulin GO:0032868 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms.	1	P47197 (/IEP)
Cellular response to hormone stimulus GO:0032870 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hormone stimulus.	1	P47197 (/IEP)
Regulation of protein localization GO:0032880 Any process that modulates the frequency, rate or extent of any process in which a protein is transported to, or maintained in, a specific location.	1	P31750 (/IDA)
Regulation of protein localization GO:0032880 Any process that modulates the frequency, rate or extent of any process in which a protein is transported to, or maintained in, a specific location.	1	P47196 (/IMP)
Regulation of protein localization GO:0032880 Any process that modulates the frequency, rate or extent of any process in which a protein is transported to, or maintained in, a specific location.	1	P31750 (/ISO)
Negative regulation of RNA splicing GO:0033119 Any process that stops, prevents, or reduces the frequency, rate or extent of RNA splicing.	1	P47197 (/IMP)
Positive regulation of peptidyl-serine phosphorylation GO:0033138 Any process that activates or increases the frequency, rate or extent of the phosphorylation of peptidyl-serine.	1	P31749 (/IDA)
Positive regulation of peptidyl-serine phosphorylation GO:0033138 Any process that activates or increases the frequency, rate or extent of the phosphorylation of peptidyl-serine.	1	P47197 (/IMP)
Positive regulation of peptidyl-serine phosphorylation GO:0033138 Any process that activates or increases the frequency, rate or extent of the phosphorylation of peptidyl-serine.	1	P31750 (/ISO)
Response to fluid shear stress GO:0034405 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluid shear stress stimulus. Fluid shear stress is the force acting on an object in a system where the fluid is moving across a solid surface.	1	P31749 (/IMP)
Response to fluid shear stress GO:0034405 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluid shear stress stimulus. Fluid shear stress is the force acting on an object in a system where the fluid is moving across a solid surface.	1	P31750 (/ISO)
Cellular response to reactive oxygen species GO:0034614 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reactive oxygen species stimulus. Reactive oxygen species include singlet oxygen, superoxide, and oxygen free radicals.	1	P31749 (/IMP)
Cellular response to reactive oxygen species GO:0034614 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reactive oxygen species stimulus. Reactive oxygen species include singlet oxygen, superoxide, and oxygen free radicals.	1	P31750 (/ISO)
Intracellular signal transduction GO:0035556 The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell.	1	P31749 (/IDA)
Intracellular signal transduction GO:0035556 The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell.	1	P31750 (/ISO)
Interleukin-18-mediated signaling pathway GO:0035655 A series of molecular signals initiated by the binding of interleukin-18 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.	1	P31749 (/IDA)
Interleukin-18-mediated signaling pathway GO:0035655 A series of molecular signals initiated by the binding of interleukin-18 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.	1	P31750 (/ISO)
Cellular response to vascular endothelial growth factor stimulus GO:0035924 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vascular endothelial growth factor stimulus.	1	P31750 (/IDA)
Cellular response to decreased oxygen levels GO:0036294 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting a decline in the level of oxygen.	1	P31750 (/IDA)
NIK/NF-kappaB signaling GO:0038061 The process in which a signal is passed on to downstream components within the cell through the NIK-dependent processing and activation of NF-KappaB. Begins with activation of the NF-KappaB-inducing kinase (NIK), which in turn phosphorylates and activates IkappaB kinase alpha (IKKalpha). IKKalpha phosphorylates the NF-Kappa B2 protein (p100) leading to p100 processing and release of an active NF-KappaB (p52).	1	P31749 (/IMP)
NIK/NF-kappaB signaling GO:0038061 The process in which a signal is passed on to downstream components within the cell through the NIK-dependent processing and activation of NF-KappaB. Begins with activation of the NF-KappaB-inducing kinase (NIK), which in turn phosphorylates and activates IkappaB kinase alpha (IKKalpha). IKKalpha phosphorylates the NF-Kappa B2 protein (p100) leading to p100 processing and release of an active NF-KappaB (p52).	1	P31750 (/ISO)
Glucose homeostasis GO:0042593 Any process involved in the maintenance of an internal steady state of glucose within an organism or cell.	1	P31750 (/IMP)
Intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator GO:0042771 A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage, and ends when the execution phase of apoptosis is triggered.	1	Q17941 (/IMP)
Positive regulation of apoptotic process GO:0043065 Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process.	1	P47196 (/IMP)
Negative regulation of apoptotic process GO:0043066 Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.	1	P31749 (/IDA)
Negative regulation of apoptotic process GO:0043066 Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.	1	P31750 (/ISO)
Negative regulation of apoptotic process GO:0043066 Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.	1	Q98TY9 (/ISS)
Negative regulation of apoptotic process GO:0043066 Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.	1	P47196 (/TAS)
Negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GO:0043154 Any process that stops, prevents, or reduces the frequency, rate or extent of a cysteine-type endopeptidase activity involved in the apoptotic process.	1	P31750 (/IDA)
Negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GO:0043154 Any process that stops, prevents, or reduces the frequency, rate or extent of a cysteine-type endopeptidase activity involved in the apoptotic process.	1	P47197 (/IMP)
Anoikis GO:0043276 Apoptosis triggered by inadequate or inappropriate adherence to substrate e.g. after disruption of the interactions between normal epithelial cells and the extracellular matrix.	1	P31749 (/NAS)
Regulation of mRNA stability GO:0043488 Any process that modulates the propensity of mRNA molecules to degradation. Includes processes that both stabilize and destabilize mRNAs.	1	P31749 (/TAS)
Protein kinase B signaling GO:0043491 A series of reactions, mediated by the intracellular serine/threonine kinase protein kinase B (also called AKT), which occurs as a result of a single trigger reaction or compound.	1	P31750 (/IGI)
Protein kinase B signaling GO:0043491 A series of reactions, mediated by the intracellular serine/threonine kinase protein kinase B (also called AKT), which occurs as a result of a single trigger reaction or compound.	1	P47197 (/IMP)
Positive regulation of blood vessel endothelial cell migration GO:0043536 Any process that activates or increases the frequency, rate or extent of the migration of the endothelial cells of blood vessels.	1	P31749 (/IDA)
Positive regulation of blood vessel endothelial cell migration GO:0043536 Any process that activates or increases the frequency, rate or extent of the migration of the endothelial cells of blood vessels.	1	P31750 (/ISO)
Positive regulation of nitric oxide biosynthetic process GO:0045429 Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nitric oxide.	1	P31750 (/ISO)
Fat cell differentiation GO:0045444 The process in which a relatively unspecialized cell acquires specialized features of an adipocyte, an animal connective tissue cell specialized for the synthesis and storage of fat.	1	P31751 (/TAS)
Positive regulation of fat cell differentiation GO:0045600 Any process that activates or increases the frequency, rate or extent of adipocyte differentiation.	1	P31749 (/IMP)
Positive regulation of fat cell differentiation GO:0045600 Any process that activates or increases the frequency, rate or extent of adipocyte differentiation.	1	P31750 (/ISO)
Negative regulation of neuron differentiation GO:0045665 Any process that stops, prevents, or reduces the frequency, rate or extent of neuron differentiation.	1	M4MD44 (/IMP)
Positive regulation of glycogen biosynthetic process GO:0045725 Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glycogen.	1	P31749 (/NAS)
Positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 Any process that activates or increases the frequency, rate or extent of epidermal growth factor receptor signaling pathway activity.	1	P31749 (/TAS)
Negative regulation of cell size GO:0045792 Any process that reduces cell size.	1	P47196 (/IDA)
Negative regulation of cell size GO:0045792 Any process that reduces cell size.	1	P31750 (/ISO)
Positive regulation of cell size GO:0045793 Any process that increases cell size.	1	Q9WUA6 (/IMP)
Negative regulation of proteolysis GO:0045861 Any process that stops, prevents, or reduces the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein.	1	P31749 (/IMP)
Negative regulation of proteolysis GO:0045861 Any process that stops, prevents, or reduces the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein.	1	P31750 (/ISO)
Positive regulation of transcription, DNA-templated GO:0045893 Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.	1	P31749 (/IMP)
Positive regulation of transcription, DNA-templated GO:0045893 Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.	1	P31750 (/ISO)
Positive regulation of vasoconstriction GO:0045907 Any process that activates or increases the frequency, rate or extent of vasoconstriction.	1	P47196 (/IMP)
Positive regulation of transcription from RNA polymerase II promoter GO:0045944 Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.	1	P31750 (/IGI)
Positive regulation of transcription from RNA polymerase II promoter GO:0045944 Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.	1	P47197 (/IMP)
Negative regulation of JNK cascade GO:0046329 Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the JNK cascade.	1	P47196 (/IDA)
Positive regulation of organ growth GO:0046622 Any process that activates or increases the frequency, rate or extent of growth of an organ of an organism.	1	P31750 (/IMP)
Protein autophosphorylation GO:0046777 The phosphorylation by a protein of one or more of its own amino acid residues (cis-autophosphorylation), or residues on an identical protein (trans-autophosphorylation).	1	P31749 (/TAS)
Positive regulation of lipid biosynthetic process GO:0046889 Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids.	1	P31749 (/IMP)
Positive regulation of lipid biosynthetic process GO:0046889 Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids.	1	P31750 (/ISO)
Insulin-like growth factor receptor signaling pathway GO:0048009 The series of molecular signals generated as a consequence of the insulin-like growth factor receptor binding to one of its physiological ligands.	1	P31749 (/IMP)
Insulin-like growth factor receptor signaling pathway GO:0048009 The series of molecular signals generated as a consequence of the insulin-like growth factor receptor binding to one of its physiological ligands.	1	P31750 (/ISO)
Positive regulation of smooth muscle cell proliferation GO:0048661 Any process that activates or increases the rate or extent of smooth muscle cell proliferation.	1	P31749 (/IDA)
Positive regulation of smooth muscle cell proliferation GO:0048661 Any process that activates or increases the rate or extent of smooth muscle cell proliferation.	1	P31750 (/ISO)
Brain morphogenesis GO:0048854 The process in which the anatomical structures of the brain are generated and organized. The brain is one of the two components of the central nervous system and is the center of thought and emotion. It is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.).	1	Q9WUA6 (/IMP)
Homeostasis of number of cells within a tissue GO:0048873 Any biological process involved in the maintenance of the steady-state number of cells within a population of cells in a tissue.	1	Q9WUA6 (/IMP)
Positive regulation of positive chemotaxis GO:0050927 Any process that activates or increases the frequency, rate or extent of the directed movement of a motile cell or organism towards a higher concentration in a concentration gradient of a specific chemical.	1	P47197 (/IDA)
Regulation of nitric-oxide synthase activity GO:0050999 Any process that modulates the activity of the enzyme nitric-oxide synthase.	1	P31749 (/TAS)
Positive regulation of nitric-oxide synthase activity GO:0051000 Any process that activates or increases the activity of the enzyme nitric-oxide synthase.	1	P31749 (/IMP)
Positive regulation of nitric-oxide synthase activity GO:0051000 Any process that activates or increases the activity of the enzyme nitric-oxide synthase.	1	P31750 (/ISO)
Positive regulation of sequence-specific DNA binding transcription factor activity GO:0051091 Any process that activates or increases the frequency, rate or extent of activity of a transcription factor, any factor involved in the initiation or regulation of transcription.	1	P31749 (/IDA)
Positive regulation of sequence-specific DNA binding transcription factor activity GO:0051091 Any process that activates or increases the frequency, rate or extent of activity of a transcription factor, any factor involved in the initiation or regulation of transcription.	1	P31750 (/ISO)
Striated muscle cell differentiation GO:0051146 The process in which a relatively unspecialized cell acquires specialized features of a striated muscle cell; striated muscle fibers are divided by transverse bands into striations, and cardiac and voluntary muscle are types of striated muscle.	1	P31750 (/IGI)
Glycogen cell differentiation involved in embryonic placenta development GO:0060709 The process in which a relatively unspecialized cell acquires specialized features of a glycogen cell of the placenta. A glycogen cell is a vacuolated glycogen-rich cell that appears in compact cell islets of the spongiotrophoblast layer.	1	P31750 (/IMP)
Labyrinthine layer blood vessel development GO:0060716 The process whose specific outcome is the progression of a blood vessel of the labyrinthine layer of the placenta over time, from its formation to the mature structure. The embryonic vessels grow through the layer to come in close contact with the maternal blood supply.	1	P31750 (/IMP)
Intracellular protein transmembrane transport GO:0065002 The directed movement of proteins in a cell, from one side of a membrane to another by means of some agent such as a transporter or pore.	1	Q60823 (/IMP)
Response to UV-A GO:0070141 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-A radiation stimulus. UV-A radiation (UV-A light) spans the wavelengths 315 to 400 nm.	1	P31749 (/IDA)
Response to UV-A GO:0070141 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-A radiation stimulus. UV-A radiation (UV-A light) spans the wavelengths 315 to 400 nm.	1	P31750 (/ISO)
Regulation of cell cycle arrest GO:0071156 Any process that modulates the rate, frequency, or extent of cell cycle arrest, the process in which the cell cycle is halted during one of the normal phases.	1	P31751 (/TAS)
Cellular response to mechanical stimulus GO:0071260 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mechanical stimulus.	1	P47196 (/IDA)
Cellular response to cadmium ion GO:0071276 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cadmium (Cd) ion stimulus.	1	P31749 (/IMP)
Cellular response to cadmium ion GO:0071276 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cadmium (Cd) ion stimulus.	1	P31750 (/ISO)
Cellular response to growth factor stimulus GO:0071363 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth factor stimulus.	1	P31750 (/IDA)
Cellular response to epidermal growth factor stimulus GO:0071364 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an epidermal growth factor stimulus.	1	P31750 (/IDA)
Cellular response to prostaglandin E stimulus GO:0071380 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin E stimulus.	1	P31750 (/IDA)
Cellular response to hypoxia GO:0071456 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.	1	P47196 (/IDA)
Cellular response to high light intensity GO:0071486 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a high light intensity stimulus.	1	Q60823 (/IMP)
Establishment of protein localization to mitochondrion GO:0072655 The directed movement of a protein to the mitochondrion or a part of the mitochondrion.	1	P31749 (/IMP)
Establishment of protein localization to mitochondrion GO:0072655 The directed movement of a protein to the mitochondrion or a part of the mitochondrion.	1	P31750 (/ISO)
Maintenance of protein location in mitochondrion GO:0072656 Any process in which a protein is maintained in a specific location in a mitochondrion, and is prevented from moving elsewhere.	1	P31749 (/IMP)
Maintenance of protein location in mitochondrion GO:0072656 Any process in which a protein is maintained in a specific location in a mitochondrion, and is prevented from moving elsewhere.	1	P31750 (/ISO)
Protein localization to plasma membrane GO:0072659 A process in which a protein is transported to, or maintained in, a specific location in the plasma membrane.	1	Q60823 (/IGI)
Positive regulation of establishment of protein localization to plasma membrane GO:0090004 Any process that increases the frequency, rate or extent of the directed movement of a protein to a specific location in the plasma membrane.	1	P31749 (/IMP)
Positive regulation of establishment of protein localization to plasma membrane GO:0090004 Any process that increases the frequency, rate or extent of the directed movement of a protein to a specific location in the plasma membrane.	1	P31750 (/ISO)
Negative regulation of release of cytochrome c from mitochondria GO:0090201 Any process that decreases the rate, frequency or extent of release of cytochrome c from mitochondria, the process in which cytochrome c is enabled to move from the mitochondrial intermembrane space into the cytosol, which is an early step in apoptosis and leads to caspase activation.	1	P31750 (/IDA)
Positive regulation of protein targeting to membrane GO:0090314 Any process that increases the frequency, rate or extent of the process of directing proteins towards a membrane, usually using signals contained within the protein.	1	Q60823 (/IMP)
Activation of GTPase activity GO:0090630 Any process that initiates the activity of an inactive GTPase through the replacement of GDP by GTP.	1	Q60823 (/IGI)
Cellular response to granulocyte macrophage colony-stimulating factor stimulus GO:0097011 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a granulocyte macrophage colony-stimulating factor stimulus.	1	P31750 (/IDA)
Execution phase of apoptosis GO:0097194 A stage of the apoptotic process that starts with the controlled breakdown of the cell through the action of effector caspases or other effector molecules (e.g. cathepsins, calpains etc.). Key steps of the execution phase are rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died.	1	P31750 (/IDA)
Retinal rod cell apoptotic process GO:0097473 Any apoptotic process in a retinal rod cell, one of the two photoreceptor cell types of the vertebrate retina.	1	Q60823 (/IMP)
Chemical synaptic transmission, postsynaptic GO:0099565 The part of synaptic transmission occurring in the post-synapse: a signal transduction pathway consisting of neurotransmitter receptor activation and its effects on postsynaptic membrane potential and the ionic composition of the postsynaptic cytosol.	1	P31749 (/NAS)
Negative regulation of protein kinase activity by protein phosphorylation GO:0100002 Any protein phosphorylation process that negatively_regulates protein kinase activity	1	P31749 (/TAS)
Positive regulation of protein localization to nucleus GO:1900182 Any process that activates or increases the frequency, rate or extent of protein localization to nucleus.	1	P31749 (/IMP)
Positive regulation of protein localization to nucleus GO:1900182 Any process that activates or increases the frequency, rate or extent of protein localization to nucleus.	1	P31750 (/ISO)
Negative regulation of neuron death GO:1901215 Any process that stops, prevents or reduces the frequency, rate or extent of neuron death.	1	P31749 (/NAS)
Cellular response to peptide GO:1901653 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide stimulus.	1	P31750 (/IDA)
Regulation of signal transduction by p53 class mediator GO:1901796 Any process that modulates the frequency, rate or extent of signal transduction by p53 class mediator.	1	P31749 (/TAS)
Regulation of cell cycle checkpoint GO:1901976 Any process that modulates the frequency, rate or extent of cell cycle checkpoint.	1	P31749 (/TAS)
Response to salt GO:1902074 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a salt stimulus.	1	Q17941 (/IGI)
Negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway GO:1902176 Any process that stops, prevents or reduces the frequency, rate or extent of an oxidative stress-induced intrinsic apoptotic signaling pathway.	1	P31749 (/NAS)
Positive regulation of I-kappaB phosphorylation GO:1903721 Any process that activates or increases the frequency, rate or extent of I-kappaB phosphorylation.	1	P31749 (/IMP)
Positive regulation of I-kappaB phosphorylation GO:1903721 Any process that activates or increases the frequency, rate or extent of I-kappaB phosphorylation.	1	P31750 (/ISO)
Cellular response to nerve growth factor stimulus GO:1990090 A process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nerve growth factor stimulus.	1	P47196 (/IDA)
Cellular response to nerve growth factor stimulus GO:1990090 A process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nerve growth factor stimulus.	1	P31749 (/IMP)
Cellular response to nerve growth factor stimulus GO:1990090 A process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nerve growth factor stimulus.	1	P31750 (/ISO)
Positive regulation of cell motility GO:2000147 Any process that activates or increases the frequency, rate or extent of cell motility.	1	P31751 (/IMP)
Positive regulation of cell motility GO:2000147 Any process that activates or increases the frequency, rate or extent of cell motility.	1	Q60823 (/ISO)
Negative regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001240 Any process that stops, prevents or reduces the frequency, rate or extent of extrinsic apoptotic signaling pathway in absence of ligand.	1	P31749 (/TAS)
Positive regulation of glucose import in response to insulin stimulus GO:2001275 Any process that activates or increases the frequency, rate or extent of glucose import in response to insulin stimulus.	1	Q60823 (/IGI)

There are 38 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

GO Term	Annotations	Evidence
Nucleus GO:0005634 A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.	8	B0LPE5 (/IDA) C9JHS6 (/IDA) J3QLS6 (/IDA) M0QZK3 (/IDA) P31749 (/IDA) P31750 (/IDA) P31751 (/IDA) P47196 (/IDA)
Cytosol GO:0005829 The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.	7	C9JHS6 (/IDA) J3QLS6 (/IDA) M0QZK3 (/IDA) P31749 (/IDA) P31751 (/IDA) P47196 (/IDA) P47197 (/IDA)
Nucleoplasm GO:0005654 That part of the nuclear content other than the chromosomes or the nucleolus.	6	P31749 (/TAS) P31750 (/TAS) P31751 (/TAS) P47196 (/TAS) P47197 (/TAS) Q63484 (/TAS)
Cytosol GO:0005829 The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.	6	P31749 (/TAS) P31750 (/TAS) P31751 (/TAS) P47196 (/TAS) P47197 (/TAS) Q63484 (/TAS)
Plasma membrane GO:0005886 The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.	6	E1B9D1 (/IDA) F1MYJ4 (/IDA) P31749 (/IDA) P31750 (/IDA) P47197 (/IDA) Q01314 (/IDA)
Plasma membrane GO:0005886 The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.	5	P31751 (/ISS) P47196 (/ISS) Q01314 (/ISS) Q6IP76 (/ISS) Q7ZX15 (/ISS)
Intracellular membrane-bounded organelle GO:0043231 Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.	5	C9JHS6 (/IDA) J3QLS6 (/IDA) M0QZK3 (/IDA) P31751 (/IDA) P47197 (/IDA)
Plasma membrane GO:0005886 The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.	4	P31749 (/TAS) P31750 (/TAS) P31751 (/TAS) Q60823 (/TAS)
Cell cortex GO:0005938 The region of a cell that lies just beneath the plasma membrane and often, but not always, contains a network of actin filaments and associated proteins.	4	P31751 (/ISS) P47197 (/ISS) Q6IP76 (/ISS) Q7ZX15 (/ISS)
Ruffle membrane GO:0032587 The portion of the plasma membrane surrounding a ruffle.	4	P31751 (/ISS) P47197 (/ISS) Q6IP76 (/ISS) Q7ZX15 (/ISS)
Cytoplasm GO:0005737 All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.	3	P31749 (/IDA) P31750 (/IDA) P47196 (/IDA)
Cytoplasm GO:0005737 All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.	3	P31749 (/ISS) Q01314 (/ISS) Q98TY9 (/ISS)
Plasma membrane GO:0005886 The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.	3	P31750 (/ISO) Q60823 (/ISO) Q9WUA6 (/ISO)
Nucleus GO:0005634 A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.	2	P31750 (/ISO) Q60823 (/ISO)
Nucleus GO:0005634 A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.	2	P47196 (/ISS) Q01314 (/ISS)
Nucleus GO:0005634 A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.	2	P31749 (/TAS) P31751 (/TAS)
Cytosol GO:0005829 The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.	2	P31750 (/ISO) Q60823 (/ISO)
Microtubule cytoskeleton GO:0015630 The part of the cytoskeleton (the internal framework of a cell) composed of microtubules and associated proteins.	2	B0LPE5 (/IDA) P31749 (/IDA)
Vesicle GO:0031982 Any small, fluid-filled, spherical organelle enclosed by membrane.	2	P31749 (/IDA) P47197 (/IDA)
Cytoplasm GO:0005737 All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.	1	P31750 (/ISO)
Cytoplasm GO:0005737 All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.	1	P31749 (/TAS)
Mitochondrion GO:0005739 A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.	1	P31750 (/IDA)
Spindle GO:0005819 The array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during mitosis or meiosis and serves to move the duplicated chromosomes apart.	1	P31750 (/IDA)
Plasma membrane GO:0005886 The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.	1	Q60823 (/IMP)
Cell-cell junction GO:0005911 A cell junction that forms a connection between two or more cells in a multicellular organism; excludes direct cytoplasmic junctions such as ring canals.	1	P31750 (/IDA)
Cell cortex GO:0005938 The region of a cell that lies just beneath the plasma membrane and often, but not always, contains a network of actin filaments and associated proteins.	1	Q60823 (/IMP)
Cytoplasmic side of plasma membrane GO:0009898 The leaflet the plasma membrane that faces the cytoplasm and any proteins embedded or anchored in it or attached to its surface.	1	Q17941 (/IDA)
Microtubule cytoskeleton GO:0015630 The part of the cytoskeleton (the internal framework of a cell) composed of microtubules and associated proteins.	1	P31750 (/ISO)
Axon GO:0030424 The long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminals and varicosities, which are sites of storage and release of neurotransmitter.	1	Q17941 (/IDA)
Dendrite GO:0030425 A neuron projection that has a short, tapering, often branched, morphology, receives and integrates signals from other neurons or from sensory stimuli, and conducts a nerve impulse towards the axon or the cell body. In most neurons, the impulse is conveyed from dendrites to axon via the cell body, but in some types of unipolar neuron, the impulse does not travel via the cell body.	1	Q17941 (/IDA)
Vesicle GO:0031982 Any small, fluid-filled, spherical organelle enclosed by membrane.	1	P31750 (/ISO)
Ruffle membrane GO:0032587 The portion of the plasma membrane surrounding a ruffle.	1	Q60823 (/IMP)
Insulin-responsive compartment GO:0032593 A small membrane-bounded vesicle that releases its contents by exocytosis in response to insulin stimulation; the contents are enriched in GLUT4, IRAP and VAMP2.	1	P47197 (/IDA)
Ciliary basal body GO:0036064 A membrane-tethered, short cylindrical array of microtubules and associated proteins found at the base of a eukaryotic cilium (also called flagellum) that is similar in structure to a centriole and derives from it. The cilium basal body is the site of assembly and remodelling of the cilium and serves as a nucleation site for axoneme growth. As well as anchoring the cilium, it is thought to provide a selective gateway regulating the entry of ciliary proteins and vesicles by intraflagellar transport.	1	P31750 (/IDA)
Neuronal cell body GO:0043025 The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites.	1	Q17941 (/IDA)
Intracellular membrane-bounded organelle GO:0043231 Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.	1	Q60823 (/ISO)
Protein complex GO:0043234 A stable macromolecular complex composed (only) of two or more polypeptide subunits along with any covalently attached molecules (such as lipid anchors or oligosaccharide) or non-protein prosthetic groups (such as nucleotides or metal ions). Prosthetic group in this context refers to a tightly bound cofactor. The component polypeptide subunits may be identical.	1	P31750 (/IDA)
Protein complex GO:0043234 A stable macromolecular complex composed (only) of two or more polypeptide subunits along with any covalently attached molecules (such as lipid anchors or oligosaccharide) or non-protein prosthetic groups (such as nucleotides or metal ions). Prosthetic group in this context refers to a tightly bound cofactor. The component polypeptide subunits may be identical.	1	P31750 (/ISO)

CATH Superfamily 2.30.29.30

Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)

Functional Families

FunFam 22238: RAC-beta serine/threonine-protein kinase A

There are 37 GO terms relating to "molecular function"

There are 273 GO terms relating to "biological process"

There are 38 GO terms relating to "cellular component"