CATH Superfamily 2.30.29.30
Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)
The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:
"Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)
".
FunFam 1956: Rab GTPase-activating protein 1
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 7 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
GTPase activator activity GO:0005096
Binds to and increases the activity of a GTPase, an enzyme that catalyzes the hydrolysis of GTP.
|
1 | Q9Y3P9 (/IDA) |
|
GTPase activator activity GO:0005096
Binds to and increases the activity of a GTPase, an enzyme that catalyzes the hydrolysis of GTP.
|
1 | A2AWA9 (/ISO) |
|
GTPase activator activity GO:0005096
Binds to and increases the activity of a GTPase, an enzyme that catalyzes the hydrolysis of GTP.
|
1 | Q9Y3P9 (/TAS) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | Q9Y3P9 (/IPI) |
|
Tubulin binding GO:0015631
Interacting selectively and non-covalently with monomeric or multimeric forms of tubulin, including microtubules.
|
1 | Q9Y3P9 (/TAS) |
|
Rab GTPase binding GO:0017137
Interacting selectively and non-covalently with Rab protein, any member of the Rab subfamily of the Ras superfamily of monomeric GTPases.
|
1 | Q9Y3P9 (/IPI) |
|
Rab GTPase binding GO:0017137
Interacting selectively and non-covalently with Rab protein, any member of the Rab subfamily of the Ras superfamily of monomeric GTPases.
|
1 | A2AWA9 (/ISO) |
There are 4 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cell cycle GO:0007049
The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division.
|
1 | Q9Y3P9 (/TAS) |
|
Regulation of GTPase activity GO:0043087
Any process that modulates the rate of GTP hydrolysis by a GTPase.
|
1 | Q9Y3P9 (/IDA) |
|
Regulation of GTPase activity GO:0043087
Any process that modulates the rate of GTP hydrolysis by a GTPase.
|
1 | A2AWA9 (/ISO) |
|
Membrane organization GO:0061024
A process which results in the assembly, arrangement of constituent parts, or disassembly of a membrane. A membrane is a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.
|
1 | Q9Y3P9 (/TAS) |
There are 5 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Centrosome GO:0005813
A structure comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle.
|
1 | Q9Y3P9 (/TAS) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | Q9Y3P9 (/IDA) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | A2AWA9 (/ISO) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | Q9Y3P9 (/TAS) |
|
Microtubule associated complex GO:0005875
Any multimeric complex connected to a microtubule.
|
1 | Q9Y3P9 (/TAS) |