CATH Superfamily 2.30.29.30
Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)
The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:
"Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)
".
FunFam 11018: Rho-type guanine nucleotide exchange factor, isofo...
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 2 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Guanyl-nucleotide exchange factor activity GO:0005085
Stimulates the exchange of guanyl nucleotides associated with a GTPase. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase.
|
6 | A8DZ19 (/ISS) A8DZ20 (/ISS) C3KGL5 (/ISS) M9PBE8 (/ISS) M9PGB1 (/ISS) Q9VIN1 (/ISS) |
|
Protein complex scaffold GO:0032947
A structural molecule activity that provides a physical support for the assembly of a multiprotein complex. The scaffold may or may not be part of the final complex.
|
6 | A8DZ19 (/IMP) A8DZ20 (/IMP) C3KGL5 (/IMP) M9PBE8 (/IMP) M9PGB1 (/IMP) Q9VIN1 (/IMP) |
There are 4 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Positive regulation of hippo signaling GO:0035332
Any process that activates or increases the frequency, rate or extent of hippo signaling.
|
6 | A8DZ19 (/IGI) A8DZ20 (/IGI) C3KGL5 (/IGI) M9PBE8 (/IGI) M9PGB1 (/IGI) Q9VIN1 (/IGI) |
|
Positive regulation of GTPase activity GO:0043547
Any process that activates or increases the activity of a GTPase.
|
6 | A8DZ19 (/ISS) A8DZ20 (/ISS) C3KGL5 (/ISS) M9PBE8 (/ISS) M9PGB1 (/ISS) Q9VIN1 (/ISS) |
|
Regulation of organ growth GO:0046620
Any process that modulates the frequency, rate or extent of growth of an organ of an organism.
|
6 | A8DZ19 (/IGI) A8DZ20 (/IGI) C3KGL5 (/IGI) M9PBE8 (/IGI) M9PGB1 (/IGI) Q9VIN1 (/IGI) |
|
Regulation of synapse organization GO:0050807
Any process that modulates the physical form of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell).
|
6 | A8DZ19 (/IMP) A8DZ20 (/IMP) C3KGL5 (/IMP) M9PBE8 (/IMP) M9PGB1 (/IMP) Q9VIN1 (/IMP) |
There are 1 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Muscle cell postsynaptic density GO:0097482
A postsynaptic specialization that is part of a neuromuscular junction.
|
6 | A8DZ19 (/IDA) A8DZ20 (/IDA) C3KGL5 (/IDA) M9PBE8 (/IDA) M9PGB1 (/IDA) Q9VIN1 (/IDA) |