The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
PUA domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 4837: Probable tRNA pseudouridine synthase B

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
TRNA-guanine(15) transglycosylase. [EC: 2.4.2.48]
Guanine(15) in tRNA + 7-cyano-7-carbaguanine = 7-cyano-7-carbaguanine(15) in tRNA + guanine.
  • Archaeal tRNAs contain the modified nucleoside archaeosine at position 15.
  • This archaeal enzyme catalyzes the exchange of guanine at position 15 of tRNA with the base preQ(0), which is ultimately modified to form the nucleoside archaeosine (cf. EC 2.6.1.97).
242 A0A075LZE9 A0A075LZE9 A0A076LDB0 A0A076LDB0 A0A089ZHQ2 A0A089ZHQ2 A0A090JX49 A0A090JX49 A0A097QUU6 A0A097QUU6
(232 more...)
Phosphoadenylyl-sulfate reductase (thioredoxin). [EC: 1.8.4.8]
Adenosine 3',5'-bisphosphate + sulfite + thioredoxin disulfide = 3'-phosphoadenylyl sulfate + thioredoxin.
  • Specific for PAPS.
  • The enzyme from Escherichia coli will use thioredoxins from other species.
  • Formerly EC 1.8.99.4.
4 A0A062VAX1 A0A062VAX1 M4YKL7 M4YKL7
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