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CATH Superfamily 2.20.25.90

ADC-like domains

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
ADC-like domains
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 3744: NADH-quinone oxidoreductase subunit G

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
NADH dehydrogenase (quinone). [EC: 1.6.5.11]
NADH + a quinone = NAD(+) + a quinol.
  • Menaquinone or other quinones can act as acceptor.
  • Inhibited by AMP and 2,4-dinitrophenol but not by dicoumarol or folic acid derivatives.
  • Formerly EC 1.6.99.5.
 1691 A0A009FXK4 A0A009GHN8 A0A009H7G0 A0A009HCH1 A0A009I894 A0A009J9C6 A0A009KQM1 A0A009LBH2 A0A009MN12 A0A009Q2N5
(1681 more...)
Transferred entry: 1.6.5.11. [EC: 1.6.99.5]
    		22 A0A066PUR1 A0A099L404 A0A0D7LUB9 A0A0E1YA59 A0A0E3ZH97 A0A0F0F3A8 A0A0M4HWP5 A0A0T9KMD2 A0A0T9PDY3 A0A0U2B2M8
    (12 more...)
    NADH:ubiquinone reductase (H(+)-translocating). [EC: 1.6.5.3]
    NADH + ubiquinone + 5 H(+)(In) = NAD(+) + ubiquinol + 4 H(+)(Out).
    • The complex is present in mitochondria and aerobic bacteria.
    • Breakdown of the complex can release EC 1.6.99.3.
    • In photosynthetic bacteria, reversed electron transport through this enzyme can reduce NAD(+) to NADH.
    		 18 A0A0T9KMD2 A0A0T9PDY3 A0A198UI05 A0A198UXU8 A0A198WSH3 A0A198XEB5 A0A198XYC9 A0A1L9EZ79 A3JDA1 A5FXJ5
    (8 more...)