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CATH Superfamily 2.20.25.90

ADC-like domains

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
ADC-like domains
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 2873: Probable oxidoreductase

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Nitrate reductase. [EC: 1.7.99.4]
Nitrite + acceptor = nitrate + reduced acceptor.
  • The Pseudomonas enzyme is a cytochrome, but the enzyme from Micrococcus halodenitrificans is an iron protein containing molybdenum.
  • Reduced benzyl viologen and other dyes bring about the reduction of nitrate.
 10 A0A0F6UBL5 A0A0F7QPK2 A0A0H3R782 A0A0P1D8T8 A0A1D5BWY3 A0A1E9C713 A0A1F0IE31 A0A1G5LW65 A0A1J0IR96 A0A1L4H1Q8
Formate dehydrogenase. [EC: 1.2.1.2]
Formate + NAD(+) = CO(2) + NADH.
  • The enzyme from most aerobic organisms is devoid of redox-active centers but that from the proteobacterium Methylosinus trichosporium contains iron-sulfur centers, flavin and a molybdenum center.
  • Together with EC 1.12.1.2, forms a system previously known as formate hydrogenlyase.
 2 A0A0H2ZE99 A0A157WPV8