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CATH Superfamily 2.20.25.10

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 6766: DNA-directed RNA polymerase subunit

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
DNA-directed RNA polymerase. [EC: 2.7.7.6]
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).
  • Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.
  • Can initiate a chain de novo.
  • In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.
  • See also EC 2.7.7.19 and EC 2.7.7.48.
 158 A0A024VFW8 A0A024VFW8 A0A024WF61 A0A024WF61 A0A024XEU3 A0A024XEU3 A0A060HVC9 A0A060HVC9 A0A060RMU6 A0A060RMU6
(148 more...)
Alpha,alpha-trehalase. [EC: 3.2.1.28]
Alpha,alpha-trehalose + H(2)O = beta-D-glucose + alpha-D-glucose.
  • The enzyme is an anomer-inverting glucosidase that catalyzes the hydrolysis of the alpha-glucosidic O-linkage of alpha,alpha- trehalose, releasing initially equimolar amounts of alpha- and beta- D-glucose.
  • It is widely distributed in microorganisms, plants, invertebrates and vertebrates.
 32 A0A0V0S0Q4 A0A0V0S0Q4 A0A0V0WYI6 A0A0V0WYI6 A0A0V0WYV0 A0A0V0WYV0 A0A0V0WZR0 A0A0V0WZR0 A0A0V0XUQ8 A0A0V0XUQ8
(22 more...)
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