The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:
"Thrombospondin type-1 (TSP1) repeat
".
FunFam 10038: ADAMTS-like 2, isoform CRA_a
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 3 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Extracellular matrix structural constituent GO:0005201
The action of a molecule that contributes to the structural integrity of the extracellular matrix.
|
1 | Q868Z9 (/IMP) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | Q86TH1 (/IPI) |
|
Microfibril binding GO:0050436
Interacting selectively and non-covalently with a microfibril, any small fibril occurring in biological material.
|
1 | Q7TSK7 (/IPI) |
There are 6 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Larval heart development GO:0007508
The process whose specific outcome is the progression of the larval heart over time, from its formation to the mature structure. In Drosophila the larval heart (dorsal vessel) is a continuous tube of mesodormal cells that runs beneath the dorsal midline of the epidermis, divided into an anterior aorta and a posterior heart proper.
|
2 | E1JHE3 (/IMP) Q9VKV3 (/IMP) |
|
Extracellular matrix organization GO:0030198
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an extracellular matrix.
|
2 | Q7TSK7 (/IMP) Q868Z9 (/IMP) |
|
Negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512
Any process that stops, prevents, or reduces the frequency, rate or extent of any TGF-beta receptor signaling pathway.
|
2 | Q7TSK7 (/IMP) Q86TH1 (/IMP) |
|
Positive regulation of extracellular matrix assembly GO:1901203
Any process that activates or increases the frequency, rate or extent of extracellular matrix assembly.
|
2 | E1JHE3 (/IMP) Q9VKV3 (/IMP) |
|
Negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512
Any process that stops, prevents, or reduces the frequency, rate or extent of any TGF-beta receptor signaling pathway.
|
1 | Q7TSK7 (/ISO) |
|
Lobar bronchus epithelium development GO:0060481
The biological process whose specific outcome is the progression of a lobar bronchus epithelium from an initial condition to its mature state. This process begins with the formation of the lobar bronchus epithelium and ends with the mature structure. The lobar bronchus epithelium is the tissue made up of epithelial cells that lines the inside of the lobar bronchus.
|
1 | Q7TSK7 (/IMP) |
There are 4 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Extracellular matrix GO:0031012
A structure lying external to one or more cells, which provides structural support for cells or tissues.
|
2 | E1JHE3 (/IDA) Q9VKV3 (/IDA) |
|
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
|
1 | Q7TSK7 (/IDA) |
|
Proteinaceous extracellular matrix GO:0005578
A layer consisting mainly of proteins (especially collagen) and glycosaminoglycans (mostly as proteoglycans) that forms a sheet underlying or overlying cells such as endothelial and epithelial cells. The proteins are secreted by cells in the vicinity. An example of this component is found in Mus musculus.
|
1 | Q7TSK7 (/IDA) |
|
Basement membrane GO:0005604
A thin layer of dense material found in various animal tissues interposed between the cells and the adjacent connective tissue. It consists of the basal lamina plus an associated layer of reticulin fibers.
|
1 | Q868Z9 (/IDA) |
