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CATH Superfamily 2.170.270.10

SET domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
SET domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 5051: Histone-lysine N-methyltransferase ATXR6

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 2 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
 2 Q8VZJ1 (/IPI) Q9FNE9 (/IPI)
Histone methyltransferase activity (H3-K27 specific) GO:0046976
Catalysis of the reaction: S-adenosyl-L-methionine + histone H3 L-lysine (position 27) = S-adenosyl-L-homocysteine + histone H3 N6-methyl-L-lysine (position 27). This reaction is the addition of a methyl group onto lysine at position 27 of the histone H3 protein.
 2 Q8VZJ1 (/IDA) Q9FNE9 (/IDA)

There are 6 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Regulation of DNA replication GO:0006275
Any process that modulates the frequency, rate or extent of DNA replication.
 2 Q8VZJ1 (/IGI) Q9FNE9 (/IGI)
Regulation of cell cycle GO:0051726
Any process that modulates the rate or extent of progression through the cell cycle.
 2 Q8VZJ1 (/IEP) Q9FNE9 (/IEP)
Histone H3-K27 methylation GO:0070734
The modification of histone H3 by addition of one or more methyl groups to lysine at position 27 of the histone.
 2 Q8VZJ1 (/IDA) Q9FNE9 (/IDA)
DNA mediated transformation GO:0009294
The introduction and uptake of foreign genetic material (DNA or RNA) into a cell, and often the expression of that genetic material.
 1 Q8VZJ1 (/IMP)
Pollen development GO:0009555
The process whose specific outcome is the progression of the pollen grain over time, from its formation to the mature structure. The process begins with the meiosis of the microsporocyte to form four haploid microspores. The nucleus of each microspore then divides by mitosis to form a two-celled organism, the pollen grain, that contains a tube cell as well as a smaller generative cell. The pollen grain is surrounded by an elaborate cell wall. In some species, the generative cell immediately divides again to give a pair of sperm cells. In most flowering plants, however this division takes place later, in the tube that develops when a pollen grain germinates.
 1 Q8VZJ1 (/IMP)
Anther dehiscence GO:0009901
The dehiscence of an anther to release the pollen grains contained within it.
 1 Q9FNE9 (/IMP)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
 2 Q8VZJ1 (/IDA) Q9FNE9 (/IDA)
Chloroplast GO:0009507
A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.
 1 Q8VZJ1 (/IDA)