View in Gene3D

CATH Superfamily 2.170.130.20

LCCL-like domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
LCCL-like domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 259: Limulus clotting factor C

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Limulus clotting factor C. [EC: 3.4.21.84]
Selective cleavage of 103-Arg-|-Ser-104 and 124-Ile-|-Ile-125 bonds in Limulus clotting factor B to form activated factor B. Cleavage of -Pro- Arg-|-Xaa- bonds in synthetic substrates.
  • From the hemocyte granules of the horseshoe crabs Limulus and Tachypleus.
  • Factor C is activated by Gram-negative bacterial lipopolysaccharides and chymotrypsin.
  • Inhibited by antithrombin III.
  • Belongs to peptidase family S1.
 2 P28175 Q26422