The process of directing proteins towards the vacuole, usually using signals contained within the protein.

The process of directing proteins towards the vacuole, usually using signals contained within the protein.

The chemical reactions and pathways resulting in the formation of ommochromes, any of a large group of natural polycyclic pigments commonly found in the Arthropoda, particularly in the ommatidia of the compound eye.

The directed movement of substances from the Golgi to early sorting endosomes. Clathrin vesicles transport substances from the trans-Golgi to endosomes.

A vesicle-mediated transport process in which cells take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle.

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a vacuole.

The directed movement of substances into, out of or within a lysosome.

The series of successive proteolytic cleavages of the Notch protein, which result in an active form of the receptor.

The directed movement of substances from endosomes to lysosomes.

The directed movement of substances from endosomes to lysosomes.

The control of viability and duration in the adult phase of the life-cycle.

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of nourishment.

The orientation of plant parts under the stimulation of gravity.

A cellular transport process in which transported substances are moved in membrane-bounded vesicles; transported substances are enclosed in the vesicle lumen or located in the vesicle membrane. The process begins with a step that directs a substance to the forming vesicle, and includes vesicle budding and coating. Vesicles are then targeted to, and fuse with, an acceptor membrane.

The directed movement of dsRNA, double-stranded ribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

The homotypic fusion of endocytic vesicles to form or add to an early endosome.

The homotypic fusion of endocytic vesicles to form or add to an early endosome.

Any process that modulates the frequency, rate or extent of assembly of the SNARE complex. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers.

The fusion of two vacuole membranes to form a single vacuole.

A process of exocytosis in which soluble proteins and other substances are initially stored in secretory vesicles for later release. It is found mainly in cells that are specialized for secreting products such as hormones, neurotransmitters, or digestive enzymes rapidly on demand.

The directed movement of substances from late endosomes to the vacuole. In yeast, after transport to the prevacuolar compartment, endocytic content is delivered to the late endosome and on to the vacuole. This pathway is analogous to endosome to lysosome transport.

Any process that stops, prevents, or reduces the frequency, rate or extent of the Notch signaling pathway.

The directed movement of substances within a cell.

The directed movement of substances into, out of or within the Golgi apparatus, mediated by vesicles.

The directed movement of substances into, out of or within the Golgi apparatus, mediated by vesicles.

The initial attachment of a transport vesicle membrane to the target membrane, mediated by proteins protruding from the membrane of the vesicle and the target membrane. Docking requires only that the two membranes come close enough for these proteins to interact and adhere.

The process in which autophagosomes, double-membraned vacuoles containing cytoplasmic material fuse with a vacuole (yeast) or lysosome (e.g. mammals and insects). In the case of yeast, inner membrane-bounded structures (autophagic bodies) appear in the vacuole. Fusion provides an acidic environment and digestive function to the interior of the autophagosome.

The directed movement of substances from late endosome to lysosome.

The directed movement of substances from late endosome to lysosome.

All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

The lipid bilayer surrounding the lysosome and separating its contents from the cell cytoplasm.

The lipid bilayer surrounding the lysosome and separating its contents from the cell cytoplasm.

A membrane-bounded organelle that receives incoming material from primary endocytic vesicles that have been generated by clathrin-dependent and clathrin-independent endocytosis; vesicles fuse with the early endosome to deliver cargo for sorting into recycling or degradation pathways.

A prelysosomal endocytic organelle differentiated from early endosomes by lower lumenal pH and different protein composition. Late endosomes are more spherical than early endosomes and are mostly juxtanuclear, being concentrated near the microtubule organizing center.

Any vesicle associated with the Golgi complex and involved in mediating transport within the Golgi or between the Golgi and other parts of the cell.

Any vesicle associated with the Golgi complex and involved in mediating transport within the Golgi or between the Golgi and other parts of the cell.

Any vesicle associated with the Golgi complex and involved in mediating transport within the Golgi or between the Golgi and other parts of the cell.

The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

The lipid bilayer surrounding an endosome.

The lipid bilayer surrounding an endosome.

The part of the cytoskeleton (the internal framework of a cell) composed of microtubules and associated proteins.

A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.

A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.

A vesicle with a coat formed of clathrin connected to the membrane via one of the clathrin adaptor complexes.

A vesicle with a coat formed of clathrin connected to the membrane via one of the clathrin adaptor complexes.

A multimeric protein complex that associates with the vacuolar membrane, late endosomal (multivesicular body) and lysosomal membranes. HOPS is a tethering complex involved in vesicle fusion.

A multimeric protein complex that associates with the vacuolar membrane, late endosomal (multivesicular body) and lysosomal membranes. HOPS is a tethering complex involved in vesicle fusion.

A multimeric protein complex that associates with the vacuolar membrane, late endosomal (multivesicular body) and lysosomal membranes. HOPS is a tethering complex involved in vesicle fusion.

A multimeric protein complex that associates with the vacuolar membrane, late endosomal (multivesicular body) and lysosomal membranes. HOPS is a tethering complex involved in vesicle fusion.

The lipid bilayer surrounding a late endosome.

The lipid bilayer surrounding a late endosome.

Any HOPS complex that is part of a vacuolar membrane.