The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
YVTN repeat-like/Quinoprotein amine dehydrogenase
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 102847: Actin-related protein 2/3 complex subunit 1A

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 9 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
5 O96622 (/IPI) P38328 (/IPI) P78774 (/IPI) Q6GNU1 (/IPI) Q9R0Q6 (/IPI)
Actin binding GO:0003779
Interacting selectively and non-covalently with monomeric or multimeric forms of actin, including actin filaments.
1 O97182 (/ISS)
Actin binding GO:0003779
Interacting selectively and non-covalently with monomeric or multimeric forms of actin, including actin filaments.
1 Q92747 (/TAS)
Structural constituent of cytoskeleton GO:0005200
The action of a molecule that contributes to the structural integrity of a cytoskeletal structure.
1 O15143 (/IDA)
Structural constituent of cytoskeleton GO:0005200
The action of a molecule that contributes to the structural integrity of a cytoskeletal structure.
1 Q9WV32 (/ISO)
Structural constituent of cytoskeleton GO:0005200
The action of a molecule that contributes to the structural integrity of a cytoskeletal structure.
1 O97182 (/ISS)
Structural constituent of cytoskeleton GO:0005200
The action of a molecule that contributes to the structural integrity of a cytoskeletal structure.
1 O15143 (/TAS)
Protein complex binding GO:0032403
Interacting selectively and non-covalently with any protein complex (a complex of two or more proteins that may include other nonprotein molecules).
1 O88656 (/IPI)
Ubiquitin binding GO:0043130
Interacting selectively and non-covalently with ubiquitin, a protein that when covalently bound to other cellular proteins marks them for proteolytic degradation.
1 P38328 (/IDA)

There are 42 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Actin filament organization GO:0007015
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments. Includes processes that control the spatial distribution of actin filaments, such as organizing filaments into meshworks, bundles, or other structures, as by cross-linking.
2 O80856 (/TAS) Q9SJW6 (/TAS)
Arp2/3 complex-mediated actin nucleation GO:0034314
The actin nucleation process in which actin monomers combine to form a new branch on the side of an existing actin filament; mediated by the Arp2/3 protein complex and its interaction with other proteins.
2 O15143 (/IDA) P78774 (/IDA)
Fc-gamma receptor signaling pathway involved in phagocytosis GO:0038096
An Fc-gamma receptor signaling pathway that contributes to the endocytic engulfment of external particulate material by phagocytes.
2 O15143 (/TAS) Q92747 (/TAS)
Ephrin receptor signaling pathway GO:0048013
The series of molecular signals generated as a consequence of an ephrin receptor binding to an ephrin.
2 O15143 (/TAS) Q92747 (/TAS)
Actin cortical patch assembly GO:0000147
Assembly of an actin cortical patch, a discrete actin-containing structure found at the plasma membrane of fungal cells.
1 P78774 (/IC)
Mitotic cytokinesis GO:0000281
A cell cycle process that results in the division of the cytoplasm of a cell after mitosis, resulting in the separation of the original cell into two daughter cells.
1 P78774 (/IMP)
Cell morphogenesis GO:0000902
The developmental process in which the size or shape of a cell is generated and organized.
1 O97182 (/IMP)
Compound eye morphogenesis GO:0001745
The morphogenetic process in which the anatomical structures of the compound eye are generated and organized. The adult compound eye is a precise assembly of 700-800 ommatidia. Each ommatidium is composed of 20 cells, identified by cell type and position. An example of compound eye morphogenesis is found in Drosophila melanogaster.
1 O97182 (/IMP)
Intracellular protein transport GO:0006886
The directed movement of proteins in a cell, including the movement of proteins between specific compartments or structures within a cell, such as organelles of a eukaryotic cell.
1 O97182 (/IMP)
Exocytosis GO:0006887
A process of secretion by a cell that results in the release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle by fusion of the vesicle with the plasma membrane of a cell. This process begins with steps that prepare vesicles for fusion with the membrane (tethering and docking) and ends when vesicle fusion is complete. This is the process in which most molecules are secreted from eukaryotic cells.
1 O96622 (/IEP)
Endocytosis GO:0006897
A vesicle-mediated transport process in which cells take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle.
1 P78774 (/IC)
Phagocytosis GO:0006909
An endocytosis process that results in the engulfment of external particulate material by phagocytes. The particles are initially contained within phagocytic vacuoles (phagosomes), which then fuse with primary lysosomes to effect digestion of the particles.
1 O96622 (/IEP)
Movement of cell or subcellular component GO:0006928
The directed, self-propelled movement of a cell or subcellular component without the involvement of an external agent such as a transporter or a pore.
1 O15143 (/TAS)
Cytoskeleton organization GO:0007010
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures.
1 O97182 (/ISS)
Actin filament organization GO:0007015
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments. Includes processes that control the spatial distribution of actin filaments, such as organizing filaments into meshworks, bundles, or other structures, as by cross-linking.
1 P38328 (/IMP)
Germarium-derived egg chamber formation GO:0007293
Construction of a stage-1 egg chamber in the anterior part of the germarium, from the progeny of germ-line and somatic stem cells. An example of this is found in Drosophila melanogaster.
1 O97182 (/IMP)
Axonogenesis GO:0007409
De novo generation of a long process of a neuron, that carries efferent (outgoing) action potentials from the cell body towards target cells. Refers to the morphogenesis or creation of shape or form of the developing axon.
1 O97182 (/IGI)
Axonal fasciculation GO:0007413
The collection of axons into a bundle of rods, known as a fascicle.
1 O97182 (/IGI)
Chaeta morphogenesis GO:0008407
The process in which the anatomical structures of the chaeta are generated and organized. A chaeta is a sensory multicellular cuticular outgrowth of a specifically differentiated cell.
1 O97182 (/IMP)
Cellular response to starvation GO:0009267
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of nourishment.
1 A0A1D8PT60 (/IMP)
Chaeta development GO:0022416
The process whose specific outcome is the progression of a chaeta over time, from its formation to the mature structure. A chaeta is a sensory multicellular cuticular outgrowth of a specifically differentiated cell.
1 O97182 (/IMP)
Actin filament-based process GO:0030029
Any cellular process that depends upon or alters the actin cytoskeleton, that part of the cytoskeleton comprising actin filaments and their associated proteins.
1 O97182 (/IMP)
Actin cytoskeleton organization GO:0030036
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins.
1 Q92747 (/TAS)
Actin filament reorganization involved in cell cycle GO:0030037
The cell cycle process in which rearrangement of the spatial distribution of actin filaments and associated proteins occurs.
1 O97182 (/IMP)
Actin filament polymerization GO:0030041
Assembly of actin filaments by the addition of actin monomers to a filament.
1 O96622 (/TAS)
Filamentous growth GO:0030447
The process in which a multicellular organism, a unicellular organism or a group of unicellular organisms grow in a threadlike, filamentous shape.
1 A0A1D8PT60 (/IMP)
Pseudocleavage involved in syncytial blastoderm formation GO:0030589
Formation of furrows in the cytoplasm between nuclei during cell cycles in embryos that contribute to the formation of the syncytial blastoderm. An example of this process is found in Drosophila melanogaster.
1 O97182 (/IMP)
Response to estradiol GO:0032355
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by estradiol, a C18 steroid hormone hydroxylated at C3 and C17 that acts as a potent estrogen.
1 O88656 (/IEP)
Cell adhesion mediated by integrin GO:0033627
The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via an integrin, a heterodimeric adhesion receptor formed by the non-covalent association of particular alpha and beta subunits.
1 O97182 (/IMP)
Arp2/3 complex-mediated actin nucleation GO:0034314
The actin nucleation process in which actin monomers combine to form a new branch on the side of an existing actin filament; mediated by the Arp2/3 protein complex and its interaction with other proteins.
1 Q9WV32 (/ISO)
Arp2/3 complex-mediated actin nucleation GO:0034314
The actin nucleation process in which actin monomers combine to form a new branch on the side of an existing actin filament; mediated by the Arp2/3 protein complex and its interaction with other proteins.
1 O97182 (/ISS)
Filamentous growth of a population of unicellular organisms in response to starvation GO:0036170
The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to deprivation of nourishment.
1 A0A1D8PT60 (/IMP)
Filamentous growth of a population of unicellular organisms in response to biotic stimulus GO:0036180
The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to a biotic (living) stimulus.
1 A0A1D8PT60 (/IMP)
Response to estrogen GO:0043627
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by an estrogen, C18 steroid hormones that can stimulate the development of female sexual characteristics.
1 O88656 (/IEP)
Actin nucleation GO:0045010
The initial step in the formation of an actin filament, in which actin monomers combine to form a new filament. Nucleation is slow relative to the subsequent addition of more monomers to extend the filament.
1 P38328 (/IDA)
Actin nucleation GO:0045010
The initial step in the formation of an actin filament, in which actin monomers combine to form a new filament. Nucleation is slow relative to the subsequent addition of more monomers to extend the filament.
1 O96622 (/TAS)
Positive regulation of Notch signaling pathway GO:0045747
Any process that activates or increases the frequency, rate or extent of the Notch signaling pathway.
1 O97182 (/IMP)
Negative regulation of dendrite morphogenesis GO:0050774
Any process that stops, prevents, or reduces the frequency, rate or extent of dendrite morphogenesis.
1 O97182 (/IMP)
Detection of temperature stimulus involved in sensory perception of pain GO:0050965
The series of events involved in the perception of pain in which a temperature stimulus is received and converted into a molecular signal.
1 O97182 (/IMP)
Positive regulation of filopodium assembly GO:0051491
Any process that activates or increases the frequency, rate or extent of the assembly of a filopodium, a thin, stiff protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal growth cone.
1 O97182 (/IMP)
Epithelium development GO:0060429
The process whose specific outcome is the progression of an epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure.
1 O97182 (/IMP)
Membrane organization GO:0061024
A process which results in the assembly, arrangement of constituent parts, or disassembly of a membrane. A membrane is a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.
1 Q92747 (/TAS)

There are 27 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Arp2/3 protein complex GO:0005885
A stable protein complex that contains two actin-related proteins, Arp2 and Arp3, and five novel proteins (ARPC1-5), and functions in the nucleation of branched actin filaments.
6 O15143 (/TAS) O80856 (/TAS) O97182 (/TAS) Q9R0Q6 (/TAS) Q9SJW6 (/TAS) Q9WV32 (/TAS)
Arp2/3 protein complex GO:0005885
A stable protein complex that contains two actin-related proteins, Arp2 and Arp3, and five novel proteins (ARPC1-5), and functions in the nucleation of branched actin filaments.
4 O15143 (/IDA) O96622 (/IDA) P38328 (/IDA) P78774 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
3 O80856 (/IDA) P78774 (/IDA) Q9SJW6 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
3 O15143 (/TAS) Q58CQ2 (/TAS) Q92747 (/TAS)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2 O80856 (/IDA) Q9SJW6 (/IDA)
Actin cytoskeleton GO:0015629
The part of the cytoskeleton (the internal framework of a cell) composed of actin and associated proteins. Includes actin cytoskeleton-associated complexes.
2 O15143 (/TAS) Q92747 (/TAS)
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
2 O15143 (/IDA) Q92747 (/IDA)
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
2 Q9R0Q6 (/ISO) Q9WV32 (/ISO)
Phagocytic cup GO:0001891
An invagination of the cell membrane formed by an actin dependent process during phagocytosis. Following internalization it is converted into a phagosome.
1 O96622 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 P78774 (/IDA)
Arp2/3 protein complex GO:0005885
A stable protein complex that contains two actin-related proteins, Arp2 and Arp3, and five novel proteins (ARPC1-5), and functions in the nucleation of branched actin filaments.
1 Q9WV32 (/ISO)
Arp2/3 protein complex GO:0005885
A stable protein complex that contains two actin-related proteins, Arp2 and Arp3, and five novel proteins (ARPC1-5), and functions in the nucleation of branched actin filaments.
1 O97182 (/ISS)
Arp2/3 protein complex GO:0005885
A stable protein complex that contains two actin-related proteins, Arp2 and Arp3, and five novel proteins (ARPC1-5), and functions in the nucleation of branched actin filaments.
1 O97182 (/NAS)
Focal adhesion GO:0005925
Small region on the surface of a cell that anchors the cell to the extracellular matrix and that forms a point of termination of actin filaments.
1 O15143 (/IDA)
Focal adhesion GO:0005925
Small region on the surface of a cell that anchors the cell to the extracellular matrix and that forms a point of termination of actin filaments.
1 Q9WV32 (/ISO)
Cell cortex GO:0005938
The region of a cell that lies just beneath the plasma membrane and often, but not always, contains a network of actin filaments and associated proteins.
1 O96622 (/IDA)
Filopodium GO:0030175
Thin, stiff, actin-based protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal or dendritic growth cone, or a dendritic shaft.
1 O96622 (/IC)
Actin cortical patch GO:0030479
An endocytic patch that consists of an actin-containing structure found at the plasma membrane in cells; formed of networks of branched actin filaments that lie just beneath the plasma membrane and assemble, move, and disassemble rapidly. An example of this is the actin cortical patch found in Saccharomyces cerevisiae.
1 P78774 (/IDA)
Phagocytic vesicle membrane GO:0030670
The lipid bilayer surrounding a phagocytic vesicle.
1 O96622 (/IDA)
Cortical actin cytoskeleton GO:0030864
The portion of the actin cytoskeleton, comprising filamentous actin and associated proteins, that lies just beneath the plasma membrane.
1 O96622 (/IC)
Pseudopodium GO:0031143
A temporary protrusion or retractile process of a cell, associated with flowing movements of the protoplasm, and serving for locomotion and feeding.
1 O96622 (/IC)
Cell leading edge GO:0031252
The area of a motile cell closest to the direction of movement.
1 O96622 (/IC)
Cell division site GO:0032153
The eventual plane of cell division (also known as cell cleavage or cytokinesis) in a dividing cell. In Eukaryotes, the cleavage apparatus, composed of septin structures and the actomyosin contractile ring, forms along this plane, and the mitotic, or meiotic, spindle is aligned perpendicular to the division plane. In bacteria, the cell division site is generally located at mid-cell and is the site at which the cytoskeletal structure, the Z-ring, assembles.
1 P78774 (/IDA)
Muscle cell projection membrane GO:0036195
The portion of the plasma membrane surrounding a muscle cell projection.
1 Q9R0Q6 (/IDA)
Tubulobulbar complex GO:0036284
Actin-based structures involved in establishing close contact between Sertoli-Sertoli cells or Sertoli-spermatids in the seminiferous tubules of the testes.
1 O88656 (/IDA)
Cell projection GO:0042995
A prolongation or process extending from a cell, e.g. a flagellum or axon.
1 O96622 (/IDA)
Cell tip GO:0051286
The region at the end of the longest axis of a cylindrical or elongated cell.
1 P78774 (/IDA)