The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Kelch-type beta propeller
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 8756: Cell polarity protein (Tea1)

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 2 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
3 P38853 (/IPI) P50090 (/IPI) P87061 (/IPI)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
1 P38853 (/IPI)

There are 17 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Negative regulation of exit from mitosis GO:0001100
Any process involved in the inhibition of progression from anaphase/telophase (high mitotic CDK activity) to G1 (low mitotic CDK activity).
2 P38853 (/IMP) P50090 (/IMP)
Negative regulation of exit from mitosis GO:0001100
Any process involved in the inhibition of progression from anaphase/telophase (high mitotic CDK activity) to G1 (low mitotic CDK activity).
2 P38853 (/IPI) P50090 (/IPI)
Regulation of cytokinesis GO:0032465
Any process that modulates the frequency, rate or extent of the division of the cytoplasm of a cell and its separation into two daughter cells.
2 P38853 (/IGI) P50090 (/IGI)
Regulation of vesicle-mediated transport GO:0060627
Any process that modulates the rate, frequency, or extent of vesicle-mediated transport, the directed movement of substances, either within a vesicle or in the vesicle membrane, into, out of or within a cell.
2 P38853 (/IMP) P50090 (/IMP)
Regulation of formin-nucleated actin cable assembly GO:0090337
Any process that modulates the rate, frequency, or extent of formin-nucleated actin cable assembly. Formin-nucleated actin cable assembly is the aggregation, arrangement and bonding together of a set of components to form a formin-nucleated actin cable. A formin-nucleated actin cable is an actin filament bundle that consists of short filaments organized into bundles of uniform polarity, and is nucleated by formins.
2 P38853 (/IGI) P50090 (/IGI)
Conjugation with cellular fusion GO:0000747
A conjugation process that results in the union of cellular and genetic information from compatible mating types. An example of this process is found in Saccharomyces cerevisiae.
1 P50090 (/IGI)
Cytogamy GO:0000755
During conjugation with cellular fusion, the process resulting in creating a single cell from complementary mating types. The localized remodeling and dissolution of external protective structures allow the fusion of the plasma membranes and cytoplasmic mixing. An example of this process is found in Saccharomyces cerevisiae.
1 P38853 (/IGI)
Cytogamy GO:0000755
During conjugation with cellular fusion, the process resulting in creating a single cell from complementary mating types. The localized remodeling and dissolution of external protective structures allow the fusion of the plasma membranes and cytoplasmic mixing. An example of this process is found in Saccharomyces cerevisiae.
1 P38853 (/IMP)
Cytogamy GO:0000755
During conjugation with cellular fusion, the process resulting in creating a single cell from complementary mating types. The localized remodeling and dissolution of external protective structures allow the fusion of the plasma membranes and cytoplasmic mixing. An example of this process is found in Saccharomyces cerevisiae.
1 P38853 (/IPI)
Regulation of cell shape GO:0008360
Any process that modulates the surface configuration of a cell.
1 P38853 (/IMP)
Cellular protein localization GO:0034613
Any process in which a protein is transported to, and/or maintained in, a specific location at the level of a cell. Localization at the cellular level encompasses movement within the cell, from within the cell to the cell surface, or from one location to another at the surface of a cell.
1 P87061 (/IMP)
Establishment or maintenance of bipolar cell polarity regulating cell shape GO:0061246
Any cellular process that results in the specification, formation or maintenance of a bipolar intracellular organization or cell growth patterns that regulates the shaping of a cell.
1 P87061 (/IMP)
Protein localization to new growing cell tip GO:1904758
A process in which a protein is transported to, or maintained in, a location within a new growing cell tip.
1 P87061 (/IMP)
Protein localization to cell tip GO:1990151
A process in which a protein is transported to, or maintained in, a location at the cell tip.
1 P87061 (/IDA)
Protein localization to cell cortex of cell tip GO:1990896
A process in which a protein is transported to, or maintained in, the cell cortex of the cell tip.
1 P87061 (/IDA)
Protein localization to cell cortex of cell tip GO:1990896
A process in which a protein is transported to, or maintained in, the cell cortex of the cell tip.
1 P87061 (/IMP)
Positive regulation of establishment or maintenance of cell polarity regulating cell shape GO:2000771
Any process that activates or increases the frequency, rate or extent of establishment or maintenance of cell polarity regulating cell shape.
1 P87061 (/IMP)

There are 16 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cellular bud tip GO:0005934
The end of a cellular bud distal to the site of attachment to the mother cell.
2 P38853 (/IDA) P50090 (/IDA)
Cellular bud neck GO:0005935
The constriction between the mother cell and daughter cell (bud) in an organism that reproduces by budding.
2 P38853 (/IDA) P50090 (/IDA)
Mating projection tip GO:0043332
The apex of the mating projection in unicellular fungi exposed to mating pheromone; site of polarized growth.
2 P38853 (/IDA) P50090 (/IDA)
Kelch-containing formin regulatory complex GO:1990615
A protein complex that regulates actin cable formation, polarized cell growth, and cytokinesis in a formin-dependent manner. In S. cerevisiae the complex is composed of Bud14p and two Kelch family proteins, Kel1p and Kel2p.
2 P38853 (/IDA) P50090 (/IDA)
Barrier septum GO:0000935
A septum which spans a cell and does not allow exchange of organelles or cytoplasm between compartments.
1 P87061 (/IDA)
Cell cortex GO:0005938
The region of a cell that lies just beneath the plasma membrane and often, but not always, contains a network of actin filaments and associated proteins.
1 P38853 (/IDA)
Microtubule cytoskeleton GO:0015630
The part of the cytoskeleton (the internal framework of a cell) composed of microtubules and associated proteins.
1 P87061 (/IDA)
Tea1 cell-end complex GO:0031500
A high molecular weight complex characterized in S. pombe containing the cell-end anchoring protein Tea1. This complex is transported to the cell ends by microtubules and is involved in bipolar growth and the maintennce of normal cell polarity.
1 P87061 (/IDA)
Cell division site GO:0032153
The eventual plane of cell division (also known as cell cleavage or cytokinesis) in a dividing cell. In Eukaryotes, the cleavage apparatus, composed of septin structures and the actomyosin contractile ring, forms along this plane, and the mitotic, or meiotic, spindle is aligned perpendicular to the division plane. In bacteria, the cell division site is generally located at mid-cell and is the site at which the cytoskeletal structure, the Z-ring, assembles.
1 P87061 (/IDA)
Growing cell tip GO:0035838
The region at either end of the longest axis of a cylindrical or elongated cell, where polarized growth occurs.
1 P87061 (/IDA)
Non-growing cell tip GO:0035839
A cell tip at which no growth takes place. For example, in fission yeast the cell end newly formed by cell division does not grow immediately upon its formation, and lacks actin cytoskeletal structures.
1 P87061 (/IDA)
Old growing cell tip GO:0035840
A cell tip which has existed for at least one complete cell cycle, and at which polarized growth occurs. For example, in fission yeast the cell end that existed prior to cell division grows immediately after division, and contains a distinctive complement of proteins including actin cytoskeletal structures.
1 P87061 (/IDA)
Cell cortex of cell tip GO:0051285
The region directly beneath the plasma membrane at the cell tip. The cell tip is the region at either end of the longest axis of a cylindrical or elongated cell.
1 P87061 (/IDA)
Cell tip GO:0051286
The region at the end of the longest axis of a cylindrical or elongated cell.
1 P87061 (/IDA)
Static microtubule bundle GO:0099070
A microtubule bundle that has a constant length, and in which microtubule sliding does not take place.
1 P87061 (/IDA)
Microtubule end GO:1990752
Any end of a microtubule. Microtubule ends differ in that the so-called microtubule plus-end is the one that preferentially grows by polymerization, with respect to the minus-end.
1 P87061 (/IDA)