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CATH Superfamily 2.120.10.80

Kelch-type beta propeller

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Kelch-type beta propeller
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 4472: N-acetylneuraminate epimerase

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
N-acetylneuraminate epimerase. [EC: 5.1.3.24]
N-acetyl-alpha-neuraminate = N-acetyl-beta-neuraminate.
  • Sialoglycoconjugates present in vertebrates are linked exclusively by alpha-linkages and are released in alpha form during degradation.
  • This enzyme accelerates maturotation to the beta form (which also occurs as a slow spontaneous reaction), which is necessary for further metabolism by the bacteria.
  • Formerly EC 5.1.3.n1.
 2 A0A0H3NP37 A1JMV0